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Autor:
Christian Eckmann, Paul M. Tulkens
Publikováno v:
Journal of Antimicrobial Chemotherapy
Bacterial skin and soft tissue infections are among the most common bacterial infections and constitute a major burden for patients and healthcare systems. Care is complicated by the variety of potential pathogens, some with resistance to previously
Publikováno v:
Journal of Antimicrobial Chemotherapy
The long-acting antiretroviral cabotegravir and rilpivirine combination has just received FDA, EMA and Health Canada approval. This novel drug delivery approach is about to revolutionize the therapy of people living with HIV, decreasing the 365 daily
Publikováno v:
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
J Antimicrob Chemother
J Antimicrob Chemother
This article provides a brief overview of drug resistance to antiviral therapy as well as known and emergent variability in key SARS-CoV-2 viral sequences. The purpose is to stimulate deliberation about the need to consider drug resistance prior to w
Publikováno v:
J Antimicrob Chemother
In 2020, new vancomycin guidelines were released, recommending the transition from trough-based to AUC24 monitoring for adult and paediatric patients. Given the resources required to achieve this transition, there has been debate about the costs and
Publikováno v:
Journal of Antimicrobial Chemotherapy
Thanks to advances in the field over the years, HIV/AIDS has now become a manageable chronic condition. Nevertheless, a new set of HIV-associated complications has emerged, related in part to the accelerated ageing observed in people living with HIV/
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 73, iss 9
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
As of March 2021, coronavirus disease 2019 (COVID-19) had caused more than 123 million infections and almost 3 million deaths worldwide. Dramatic advances have been made in vaccine development and nonpharmaceutical interventions to stop the spread of
Publikováno v:
Clin Infect Dis
Background Invasive fungal infections in the United States are chronically underdiagnosed and a lack of coordinated surveillance makes the true burden of disease difficult to determine. The purpose of this analysis was to capture mortality-associated
Publikováno v:
Clinical Infectious Diseases. 74:352-358
Coronavirus disease 2019 (COVID-19) vaccine trials provide valuable insight into the safety and efficacy of vaccines, with individually randomized, placebo-controlled trials being the gold standard in trial design. However, a myriad of variables must
Publikováno v:
J Infect Dis
Antiretroviral therapy effectively controls human immunodeficiency virus (HIV) replication but it is unable to fully eradicate the HIV reservoir and treatment must be life-long. Progress toward a strategy for HIV remission will require overcoming key
Autor:
Gillian Taormina, Kellie S. Reynolds, Ramya Gopinath, Yuliya Yasinskaya, Sumati Nambiar, Philip Colangelo, Jason N. Moore
Publikováno v:
Clinical Infectious Diseases. 73:2335-2340
Pathogenesis of neonatal candidiasis (NC) is distinct from systemic candidiasis in adults and older pediatric patients due to the significant incidence of central nervous system involvement in neonates. Thus, although adequate and well-controlled tri