Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Steven G. DuBois"'
Autor:
David S. Ziegler, Cornelis M. van Tilburg, Steven G. DuBois, Juneko E. Grilley-Olson, David M. Hyman, Sébastien Perreault, N. Brega, Andrej Lissat, François Doz, Birgit Geoerger, Shivani Nanda, Valentina Boni, Makoto Tahara, David S. Hong, Alexander Drilon, Hyoung Jin Kang, Antoine Italiano, Michael Capra, Ariadna Holynskyj
Publikováno v:
Neuro Oncol
BACKGROUND TRK fusions are oncogenic drivers of a variety of tumors, many of which can involve the central nervous system (CNS). Larotrectinib is a selective TRK inhibitor FDA-approved for the treatment of TRK fusion cancers (Drilon et al., NEJM 2018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c97c5ab6be18d7692e4e2377b9f39d4
https://europepmc.org/articles/PMC6847856/
https://europepmc.org/articles/PMC6847856/
Autor:
Steven G. DuBois, Jeanenne J. Nelson, Kristina Danga, Christopher A. French, Arindam Dhar, Robert I. Haddad, Nicole G. Chau, Clement Ma, Stephen E. Sallan, Geoffrey I. Shapiro, Valentina Nardi, Ryan Barrette, Hasan Al-Sayegh, Christopher S. Lathan
Publikováno v:
JNCI Cancer Spectrum
BackgroundNUT midline carcinoma, renamed NUT carcinoma (NC), is an aggressive squamous cancer defined by rearrangement of the NUTM1 gene. Although a subset of patients can be cured, for the majority of patients the prognosis is grim. We sought to cla
Autor:
Karen J. Marcus, Rachel L. Wolfson, Andrzej Niemierko, Steven G. DuBois, Daphne A. Haas-Kogan, William L. Hwang
Background Neuroblastoma is the most common pediatric extracranial solid tumor. Within conventional risk groups, there is considerable heterogeneity in outcomes, indicating the need for improved risk stratification. Methods In this study we analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d4c5da3b00c6a8769fd82f8c05af65
https://europepmc.org/articles/PMC6624164/
https://europepmc.org/articles/PMC6624164/
Autor:
Adam C. Resnick, Sabine Mueller, Jing Ni, Whitney Fitts, Dipanjan Chowdhury, Xiaodong Yang, Sharmistha Pal, Pratiti Bandhopadhayay, John A. Alberta, Steven G. DuBois, Jean J. Zhao, David Kozono, Kevin X. Liu, Keith L. Ligon, Nathalene Truffaux, Jie Bian, William A. Weiss, Daphne A. Haas-Kogan
Pediatric high-grade gliomas (pHGGs) and diffuse intrinsic pontine gliomas (DIPGs), portend a poor prognosis and are particularly recalcitrant to standard treatment. Aberrant chromatin remodeling and activation of the phosphatidylinositol 3-kinase (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eec997719189bef6bb2a709aee65354
https://europepmc.org/articles/PMC6012600/
https://europepmc.org/articles/PMC6012600/
Autor:
Daphne A. Haas-Kogan, Steven G. DuBois, Whitney Fitts, Jing Ni, Sabine Mueller, John A. Alberta, Jean J. Zhao, Xiaodong Yang, Sharmistha Pal, David Kozono
INTRODUCTION: We sought rational targeted agents that exhibit single agent activity and sensitize pediatric high-grade gliomas (pHGG) to radiation (RT). We investigated a novel dual inhibitor of class I and II histone deacetylases and class I PI3Ks i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e1ffa463f8236ea50b8a2ae7ab292e
https://europepmc.org/articles/PMC5475203/
https://europepmc.org/articles/PMC5475203/