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Publikováno v:
Neuro-oncology Advances
Melanoma is the most aggressive of the common forms of skin cancer. Metastasis to the central nervous system is one of the most common and deadly complications of this disease. Historically, melanoma patients with brain metastases had a median surviv
Publikováno v:
Neuro-oncology Advances
Brain metastases are a common occurrence in both non-small cell and small cell lung cancer with the potential to affect quality of life and prognosis. Due to concerns about the accessibility of the central nervous system by systemic chemotherapy agen
Autor:
Meng Meng Fan, Koji Takahashi, Makoto Arai, Izumi Ohno, Chikashi Ishioka, Yuichi Takiguchi, Akinobu Tawada
Publikováno v:
Japanese Journal of Clinical Oncology
Background According to a questionnaire sent to Designated Cancer Care Hospitals in Japan in 2013, only 39.4% of the institutes had medical oncology departments. Furthermore, most of these medical oncology departments were primarily responsible for t
Autor:
Nicholas McQuillan, Antonios N. Pouliopoulos, Stergios Zacharoulis, Hong-Jian Wei, Ethan Bendau, Elisa E. Konofagou, Zachary K. Englander, Andrea Webster, Nina Yoh, Masih Tazhibi, Cheng-Chia Wu
Publikováno v:
Neuro Oncol
Diffuse midline gliomas (DMG) are pediatric tumors with dismal prognosis. When these tumors emerge in the brainstem, there exists no feasible method of surgical resection or systemic intervention, making ionizing radiation the sole therapeutic avenue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f4c1009dd76d6db08cb7d80cc577fc
https://europepmc.org/articles/PMC8598601/
https://europepmc.org/articles/PMC8598601/
Autor:
Aurora Lopez-Rosas, Mark Dapash, Jason Miska, Maciej S. Lesniak, Brandyn Castro, David Hou, Yu Han, Catalina Chang, Peng Zhang, Aida Rashidi
Publikováno v:
Neuro Oncol
While immunotherapy is used clinically to treat many cancers, its translation into brain tumors remains elusive. The importance of B cells in cancer immunity has become increasingly clear, and we previously developed a B cell-based cellular vaccine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ce0439c38570859e80738b5a242f22
https://europepmc.org/articles/PMC8598464/
https://europepmc.org/articles/PMC8598464/
Publikováno v:
Neuro Oncol
Medulloblastomas in most patients are distinctively sensitive to radiation therapy, but the mechanisms that mediate this sensitivity are unclear. Current treatments still fail 20%-60% of patients with SHH medulloblastoma and can leave survivors with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cff140f7288150ec62468ae3d7f2af
https://europepmc.org/articles/PMC8598465/
https://europepmc.org/articles/PMC8598465/
Autor:
L. Nicolas Gonzalez Castro, Kevin Petrecca, Zeyu Chen, Joshua D'Antonio, Bradley E. Bernstein, Tyler E. Miller, Julia A. Verga, Charles Couturier, Mario Suva, Chadi El Farran
Publikováno v:
Neuro Oncol
Recent breakthroughs in immunotherapy have revolutionized treatment for many types of cancer, but unfortunately trials of these therapies have failed to provide meaningful life-prolonging benefit for brain tumor patients, potentially due to abundant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559268d0f9e0ba97c51e5cd4243a6296
https://europepmc.org/articles/PMC8598421/
https://europepmc.org/articles/PMC8598421/
Autor:
Gregor Hutter, Heinz Läubli, Michal A. Stanczak, Marta McDaid, Tomás A Martins, Marie-Françoise Ritz, Philip Schmassmann, Tala Shekarian
Publikováno v:
Neuro Oncol
Recently, ‘don’t eat me’-signals like CD47 have emerged as novel innate immune checkpoints, enabling cancer cells to evade clearance by phagocytes such as monocyte-derived macrophages (MDM) or microglia (MG). Here, we aim at defining the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac61fbf5369a0748c302c28ed5149a4
https://europepmc.org/articles/PMC8598774/
https://europepmc.org/articles/PMC8598774/
Autor:
Hideyuki Hongo, Yumiko Tayama, Hironori Nagata, Tomio Inoue, Kumiko Tanaka, Ryoko Suzuki, Masaharu Hata, Harumitsu Hashimoto, Shoko Takano, Kengo Matsui, Motoko Omura
Publikováno v:
Journal of Radiation Research
Intensity-modulated radiation therapy (IMRT) delivers an excellent dose distribution compared with conventional three-dimensional conformal radiation therapy (3D-CRT) for postoperative radiation including the lymph nodes in breast cancer patients. Th
Autor:
Naoyuki Shigematsu, Wakana Tamaki, Hiroshi Igaki, Koji Inaba, Shigenobu Suzuki, Yoshiaki Takagawa, Yuko Nakayama, Kana Takahashi, Jun Itami, Naoya Murakami
Publikováno v:
Journal of Radiation Research
The current study retrospectively analyzed the results of radiotherapy for clinically localized sebaceous carcinoma of the eyelid.We reviewed records of 83 patients with histologically confirmed sebaceous carcinoma who were treated radiotherapeutical