Zobrazeno 31 - 40
of 122
pro vyhledávání: ''
Autor:
Michael N. Hall, Claudia Cavelti-Weder, Martin Reincke, Fabian Meienberg, Thilo Burkard, Felix Beuschlein, Denise V. Kratschmar, Marta M. Swierczynska, Matthias Hepprich, Beckey Trinh, Eleonora Seelig, Alex Odermatt, Marc Y. Donath, Matthias J. Betz
Context Mammalian target of rapamycin complex 1 (mTORC1) activity is often increased in the adrenal cortex of patients with primary aldosteronism (PA), and mTORC1 inhibition decreases aldosterone production in adrenocortical cells, suggesting the mTO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf20a64032579551a749b12fc20ba8a8
Autor:
Justin Chiong, David Back, Rajith K. R. Rajoli, Andrew Owen, Paul Curley, Charles Flexner, Marco Siccardi
Publikováno v:
J Infect Dis
JOURNAL OF INFECTIOUS DISEASES
JOURNAL OF INFECTIOUS DISEASES
BACKGROUND: Cabotegravir and rilpivirine are 2 long-acting (LA) antiretrovirals that can be administered intramuscularly; their interaction with rifampicin, a first-line antituberculosis agent, has not been investigated. The aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18812cb7767cabef5cf22512dad923aa
https://europepmc.org/articles/PMC6500558/
https://europepmc.org/articles/PMC6500558/
Autor:
Julie Strizki, Albert Y. Liu, Kailazarid Gomez, Melissa Peda, Cindy Jacobson, Charlene S. Dezzutti, M.A. Beamer, Jingyang Zhang, Peter L. Anderson, Jeanna M. Piper, Theresa Wagner, Zhenyu Pan
Background Vaginal rings (VRs) are a promising approach for sustained delivery of antiretroviral (ARV) medication to prevent human immunodeficiency virus (HIV) infection in women. Combination ARV VRs could increase efficacy. Methods MTN-028, a phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9458bb63f38d7b95e203076b915aadc5
https://europepmc.org/articles/PMC6424086/
https://europepmc.org/articles/PMC6424086/
Autor:
Douglas R. Rank, Jon Armstrong, Leanne B. Gasink, Jan Pachl, Helen Broadhurst, John E. Mazuski, Lily Llorens, Greg Stone, Paul Newell
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
In this randomized phase 3 trial, ceftazidime-avibactam plus metronidazole was noninferior to meropenem in treating complicated intra-abdominal infection, with similar efficacy against ceftazidime-resistant and ceftazidime-susceptible pathogens and n
Autor:
Erhard van der Vries, Martin Schutten, Dennis K. M. Ip, J.D. Zhang, Benjamin J. Cowling, Krzysztof Wojtowicz, Xiao Tong, Charles A. Boucher
Publikováno v:
Journal of Infectious Diseases, 213(2), 183-190. Oxford University Press
Background. Little is known about how influenza infections caused by B/Victoria and B/Yamagata virus lineages compare with respect to disease course and susceptibility to antiviral therapy. Methods. Data from patients with influenza B infections from
Autor:
Erin Duffy, Purvi Mehra, Sue Cammarata, Jeff Kingsley, John Pullman, Eugenia Henry, Laura Lawrence
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Delafloxacin is an investigational anionic fluoroquinolone being developed to treat infections caused by Gram-positive and -negative organisms. This clinical trial evaluated the efficacy and safety of delafloxacin in the treatment of acute
Autor:
Susumu Kodaira, Kazuaki Sasaki, Yoshiyuki Yamaguchi, Takayuki Morita, Genichi Nishimura, Sotaro Sadahiro, T. Tsuchiya, Seiji Sato, Hisashi Usuki, Junji Matsuoka, Keiji Koda, Chikuma Hamada, Kenji Katsumata, Ken Kondo, Yoshihiro Kakeji, Hideo Baba
Publikováno v:
Annals of Oncology
While adjuvant chemotherapy is preferable for colon cancer, treatment duration is controversial. This phase III trial is investigated optimal duration of adjuvant chemotherapy for Stage IIB/III colon cancer. Eighteen-month treatment with UFT/LV did n
Publikováno v:
Pain Medicine: The Official Journal of the American Academy of Pain Medicine
Autor:
Christine E. MacBrayne, Sharon M Seifert, Peter L. Anderson, Marion G. Peters, Jose R Castillo-Mancilla, Diana M. Brainard, Raymond T. Chung, Arthur Y. Kim, Michael Hughes, Daniel S. Fierer, Kristen M. Marks, Susanna Naggie, Jennifer J. Kiser, Lane R. Bushman
BACKGROUND: The nucleotide analogues tenofovir and sofosbuvir are considered to have low potential for drug interactions. OBJECTIVES: To determine the effect of sofosbuvir-based HCV treatment on plasma concentrations of tenofovir and cellular concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba94fda24efa618dc7f274ed8cc25ec4
https://europepmc.org/articles/PMC6054189/
https://europepmc.org/articles/PMC6054189/
Autor:
Kimberly K. Scarsi, Marco Siccardi, Courtney V. Fletcher, David Back, Mohammed Lamorde, Kristin M. Darin, Owain Roberts, Rajith K. R. Rajoli, Andrew Owen
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background HIV-positive women receiving efavirenz-based ART and levonorgestrel contraceptive implants are at risk of low levonorgestrel exposure and unintended pregnancy. Objectives To investigate clinically applicable dose-adjustment strategies to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a47b2d4bf0c0d418daa39a74d0e2e32
http://livrepository.liverpool.ac.uk/3018224/1/dkx515-proof.pdf
http://livrepository.liverpool.ac.uk/3018224/1/dkx515-proof.pdf