Zobrazeno 1 - 10
of 57
pro vyhledávání: ''
Autor:
Ravindra K. Gupta, Judith Breuer, Sunando Roy, Caroline A. Sabin, Obinna Ogbanufe, Man Charurat, Rawlings Datir, Fati Murtala-Ibrahim, Patrick Dakum, Vivian Kwaghe, Nicaise Ndembi, Kate El Bouzidi, Dan Frampton
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background Deep sequencing could improve understanding of HIV treatment failure and viral population dynamics. However, this tool is often inaccessible in low- and middle-income countries. Objectives To determine the genetic patterns of resistance em
Autor:
Alexander W. Kay, Sandile Dlamini, H. Lester Kirchner, Velephi Okello, Bhekumusa Lukhele, Nobuhle Mthethwa, Neil Thivalapill, Tandzile T Simelane, Anna M. Mandalakas
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Antiretroviral therapy (ART) regimens that contain dolutegravir (DTG) have been associated with increases in body mass index (BMI) in adults. However, this relationship has not been well described in adolescents. Methods In a retrospective
Autor:
Michael P. Dubé, Grace A. McComsey, John R. Koethe, Carlee Moser, James H. Stein, Todd T. Brown, Theodoros Kelesidis, Judith S. Currier
Publikováno v:
Clin Infect Dis
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 74, iss 5
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 74, iss 5
BackgroundThe adipokines leptin and adiponectin, produced primarily by adipose tissue, have diverse endocrine and immunologic effects, and circulating levels reflect adipocyte lipid content, local inflammation, and tissue composition. We assessed rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9082f8df2fdf1582eb3710b11d6d5d
https://europepmc.org/articles/PMC8906713/
https://europepmc.org/articles/PMC8906713/
Autor:
Evan Tzanis, Amy Manley, Paul C. McGovern, George Sakoulas, Paul B. Eckburg, Judith N. Steenbergen, Fredrick M. Abrahamian, Anita Das
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Within the last decade, methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a frequent cause of purulent skin and soft tissue infections. New therapeutic options are being investigated for these infections. Methods We report
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Through improved understanding of the structure-activity relationship attributes of fluoroquinolones, molecule development has improved efficacy, safety, and tolerability of the class. Adverse events (AEs) associated with the fluoroquinolo
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Delafloxacin is an oral or intravenous (IV) antibiotic indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI), including both gram-positive (including methicillin-resistant Staphylococcus aureus [MRSA])
Autor:
Sophie Degroote, Konstantinos Mantzarlis, Koen Boussery, Polychronis Malliotakis, Vasileios Koulouras, Despoina Koulenti, Pieter Colin, Feifan Xie, Stijn Blot, Jan Van Bocxlaer
Publikováno v:
Journal of Antimicrobial Chemotherapy, 74(3), 667-674. Oxford University Press
Objectives: Altered linezolid pharmacokinetics (PK) in obese individuals has been hypothesized in previous studies. However, specific dosing recommendations for this population are still lacking. The main goal of this study was to evaluate PK/pharmac
Autor:
Kenneth R. Lawrence, Philippe Montravers, Angie Sway, David C. Evans, Janis Gardovskis, Larry Tsai, Joseph S. Solomkin
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Increasing antimicrobial resistance among pathogens that cause complicated intraabdominal infections (cIAIs) supports the development of new antimicrobials. Eravacycline, a novel member of the fluorocycline family, is active against multid
Autor:
Francesca Vichi, Federica Giammarino, Franco Maggiolo, Maurizio Zazzi, Antonella Castagna, Alessia Giannini, Andrea Poli, Giulio Maria Corbelli, Francesco Saladini, Andrea Galli, Alba Bigoloni, Maria Mercedes Santoro
Objectives Fostemsavir is the prodrug of the HIV-1 attachment inhibitor temsavir and is currently under clinical assessment in heavily treatment-experienced patients with limited therapeutic options. We evaluated the genotypic and phenotypic suscepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd5fcfcadffd3ef5034c27ca428a23e
Autor:
Joel Tarning, Kalayanee Chairat, Borimas Hanboonkunupakarn, Daniel Blessborn, Warunee Hanpithakpong, Podjanee Jittamala, Sasithon Pukrittayakamee, Nicholas J. White, Nicholas P. J. Day
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Characterization of the pharmacokinetic properties of the enantiomers of primaquine and carboxyprimaquine following administration of racemic primaquine given alone and in combination with commonly used antimalarial drugs. Methods Enantiom