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Publikováno v:
Alcohol and Alcoholism (Oxford, Oxfordshire)
Aims The aim of this study was to assess the efficacy of self-administered intranasal oxytocin on alcohol dependence after detoxification. Methods In a double-blind, randomized, placebo-controlled trial, 38 patients fulfilling the criteria for ICD-10
Autor:
Joanne Stocks, Weiya Zhang, Monica S M Persson, Michael Doherty, Gwen Sascha Fernandes, David A. Walsh, Aliya Sarmanova
Objectives To determine individual responses to ibuprofen gel or capsaicin cream for painful, radiographic knee OA using a series of n-of-1 trials. Methods Twenty-two participants were allocated 5% ibuprofen gel (A) and 0.025% capsaicin cream (B) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9f8f747b773d9b35a11521c327785f
Autor:
Catherine Scart-Grès, Jean-Charles Schwartz, Beatrice Setnik, Michael McDonnell, Philippe Robert, Jeffrey M Dayno, Catherine Mills
Publikováno v:
Sleep
Objectives To evaluate the human abuse potential of pitolisant, a selective histamine 3 (H3)-receptor antagonist/inverse agonist recently approved by the US Food and Drug Administration for the treatment of excessive daytime sleepiness in adult patie
Autor:
Peter S. Hendricks, Karen L. Cropsey, Lindsay R. Trent, Charles B. Clark, Erin N. Stevens, Adrienne C. Lahti
Introduction Confirming abstinence during smoking cessation clinical trials is critical for determining treatment effectiveness. Several biological methods exist for verifying abstinence (e.g., exhaled carbon monoxide [CO], cotinine), and while cotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fa99aaf8874645d6ab052ddebab714
https://europepmc.org/articles/PMC4207872/
https://europepmc.org/articles/PMC4207872/
Autor:
Sunny A. Linnebur, Jennifer J. Kiser, Paul Maroni, Graham Ray, Jacob A. Langness, Kyle P. Hammond, Craig Nielsen
A 44 year-old Caucasian male presented to the emergency department with a three day history of priapism requiring a surgically performed distal penile shunt. A drug-drug interaction is the suspected cause whereby CYP3A4 inhibition by boceprevir led t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3065ed6e8f25fea27b8e4b889f56678
https://europepmc.org/articles/PMC4049070/
https://europepmc.org/articles/PMC4049070/
Smokers with a faster rate of nicotine metabolism, estimated using the ratio of 3'-hydroxycotinine (3-HC) to cotinine, have lower plasma nicotine levels and are more likely to relapse with 21 mg nicotine patch therapy, than smokers with slower rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d363ba211ed86d7c2516cb4ffc2865e8
https://europepmc.org/articles/PMC3545715/
https://europepmc.org/articles/PMC3545715/
Publikováno v:
Frei, F. J.; Zbinden, A. M.; Thomson, D. A.; Rieder, H. U. (1991). Is the end-tidal partial pressure of isoflurane a good predictor of its arterial partial pressure? British journal of anaesthesia, 66(3), pp. 331-339. Oxford University Press 10.1093/bja/66.3.331
End-tidal partial pressure of isoflurane (PE'iso) may be used as a measure of anaesthetic depth. During uptake, an arterial partial pressure (Paiso) which is considerably less than PE'iso (Paiso/PE'iso much less than 1) leads to underestimation of de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed43f305a860820a93638a71d55c1345