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pro vyhledávání: '"Stephen G. Miller"'
Autor:
Bernard D. King, Stephen G. Miller, Minako Ishibashi, Masahiro Koseki, David Masson, Christopher J. Larson, Alan R. Tall
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:2054-2060
Objectives— Increasing HDL levels is a potential strategy for the treatment of atherosclerosis. Methods and Results— ITX5061, a molecule initially characterized as a p38 MAPK inhibitor, increased HDL-C levels by 20% in a human population of hyper
Autor:
Stephen G. Miller, Christopher J. Larson, Crowley Constance A, Bernard D. King, Jan Lundström, Kent E Prior
Publikováno v:
Circulation. 116
Introduction: KC706 is a novel p38 MAP kinase inhibitor with anti-inflammatory properties. In rats and monkeys, KC706 administration was associated with a 50 – 60% ↑ in HDL-C. Because HDL-C is an important target for the treatment of CV disease a