Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Phillip A. Dennis"'
Autor:
Adam R. Metwalli, Maria J. Merino, Cathy D. Vocke, Brian Shuch, Christopher J. Ricketts, Phillip A. Dennis, Lindsay A. Middelton, W. Marston Linehan, Takefumi Komiya, Eric C. Kauffman
Publikováno v:
Journal of Urology. 190:1990-1998
Cowden syndrome is a hereditary cancer syndrome associated with a germline mutation in PTEN. Patients are predisposed to multiple malignancies including renal cell carcinoma.Patients with Cowden syndrome were evaluated as part of a clinical protocol.
Autor:
Alonso Heredia, Joell J. Gills, Joseph Bryant, Robert R. Redfield, Shigeru Kawabata, Phillip A. Dennis
Publikováno v:
AIDS. 29:633-635
Many HIV patients on antiretroviral therapy have controlled viremia and restored (albeit partially) immunity. Yet, they have high rates of lung cancer, even after controlling for smoking. We tested the hypothesis that HIV proteins accelerate developm
Autor:
Phillip A. Dennis, Gideon M. Blumenthal, Debra S Regier, Asli Kalin, Melissa A. Merideth, Pamela Stratton
Publikováno v:
Obstetrics & Gynecology. 121:461-464
Cowden syndrome is an autosomal-dominant condition characterized by hamartomas arising from all three embryonic layers and an increased lifetime risk of developing several types of cancer.1 The prevalence of Cowden syndrome is thought to be at least
Autor:
Wendy B. Bernstein, Phillip A. Dennis
Publikováno v:
Current Opinion in HIV and AIDS. 3:666-675
Although designed to target only the HIV protease, HIV protease inhibitors induce toxicities in patients such as insulin resistance and lipodystrophy that suggest that protease inhibitors have other targets in mammalian cells. Akt controls insulin si
Publikováno v:
Anti-Cancer Drugs. 18:861-874
In an effort to improve therapeutic options in cancer, many investigational drugs are being developed to inhibit signaling pathways that promote the survival of cancer cells. The prototypic pathway that promotes cellular survival is the phosphoinosit