Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Misa Graff"'
Autor:
Christy L Avery, Annie Green Howard, Harold H Lee, Moa P Lee, Anna F Ballou, Laura M Raffield, Rina Yarosh, Kari E North, Penny Gordon-Larsen, Misa Graff
Publikováno v:
Circulation. 145
Introduction: Experimental and observational evidence suggests that aberrant branched chain amino acid (BCAA; leucine, isoleucine, and valine) metabolism promotes insulin resistance and downstream disease, prompting interest in BCAA catabolism as a t
Autor:
José Maria Santos, Ann Von Holle, Estela Blanco, Bárbara Angel, Saroja Voruganti, Misa Graff, Sheila Gahagan, Raquel Burrows, Annie Green Howard, Kari E. North, Anne E. Justice, Betsy Lozoff
Publikováno v:
Circulation. 137
Background: The postnatal period can function as a window of time for metabolic programming. As evidence from human observational studies is scarce, we examined the role of postnatal weight, length (linear growth), and weight-for-length (WFL) growth
Autor:
Anne E. Justice, Annie Green Howard, Saroja Voruganti, Sheila Gahagan, Raquel Burrows, Kari E. North, Ann Von Holle, Estela Blanco, Misa Graff, Betsy Lozoff
Publikováno v:
Circulation. 137
Introduction: Growth in early infancy is hypothesized to affect chronic disease risk factors later in life. To date, most reports draw on European ancestry cohorts with few observations of early growth. To determine if previous findings generalize to
Publikováno v:
Circulation. 135
Introduction: Endothelial NO synthase ( eNOS ) gene polymorphism at position 894 (G>T, Glu298Asp ) resulting in a T allele is related to higher blood pressure (BP) levels, but the association of Glu298Asp and temporal increase in BP in adulthood has
Autor:
Ann Von Holle, Anne Justice, Kari E North, Bárbara Angel, Estela Blanco, Sheila Gahagan, Misa Graff, José Santos
Publikováno v:
Circulation. 135
Dyslipidemia is an important risk factor for chronic cardiometabolic diseases. Lipid traits are highly heritable and there are currently >185 established loci influencing lipid levels in adults. Recent studies have confirmed that variants associated
Autor:
Leslie A. Lange, Kari E. North, Misa Graff, Karen L. Mohlke, Kristin M Young, Kathleen Mullan Harris, Ethan M. Lange, Penny Gordon Larsen, Andrea S. Richardson
Publikováno v:
Circulation. 129
Introduction: Glycated hemoglobin (HbA1c) is a marker of long-term glycemic control, and elevated HbA1c is a risk factor for type 2 diabetes and cardiovascular disease. Few genome-wide association studies(GWAS) have been performed for HbA1c, although
Autor:
Tarunveer S. Ahluwalia, Nancy L. Heard-Costa, Quibin Qi, Lu Qi, Paul W. Franks, Kari E. North, Ingrid B. Borecki, Jake Czajkowski, Keri L. Monda, L. Xue, David Hadley, Anubha Mahajan, L. Adrienne Cupples, Ruth J. F. Loos, Thomas W. Winkler, Julius S. Ngwa, Tuomas O. Kilpeläinen, Anne E. Justice, Kristin L. Young, Misa Graff
Publikováno v:
Circulation. 129
Visceral fat and smoking are important risk factors for CVD and other long-term poor health outcomes. Central adiposity is frequently assessed in population studies using waist-to-hip ratio adjusted for BMI (WHRadjBMI). Genome-wide association studie
Autor:
Christina L Wassel, Quenna Wong, Man Li, Robert J Goodloe, Misa Graff, Ran Tao, Yaming Shao, Dana C Crawford, Steve Buyske, Petra Buzkova, Nancy S Jenny, Suzette J Bielinski, James S Pankow, Stephen S Rich, Ida Chen, Kent D Taylor, Josyf Mychaleckyj, Anastasia Wise, Joachim H Ix, Dena Rifkin, Heather Junkins, Myriam Fornage, Linda Kao, Kari E North, Nora Franceschini
Publikováno v:
Circulation. 129
Several loci have been discovered and replicated for urine albumin-creatinine ratio (ACR), a measure of kidney function, in European populations; however, other ethnic populations such as African-Americans have been less studied for this trait. We ex
Autor:
Ulrike Peters, Richard S. Cooper, Charles Kooperberg, Carmen R. Isasi, Lynne R. Wilkens, JoAnn E. Manson, Jian Gong, Lewis H. Kuller, Mark Leppert, Steve Buyske, Marguerite R. Irvin, Kari E. North, Rachel H. Mackey, Praveen Sethupathy, Petra Buzkova, Lucia A. Hindorff, Misa Graff, Sachiko Yoneyama, Martha L. Daviglus, Cora E. Lewis, Denise K. Houston, Unhee Lim, C. Charles Gu, Rongling Li, Myriam Fornage
Publikováno v:
Circulation. 129
Introduction: Waist-to-hip ratio (WHR) is associated with cardiometabolic disease and its risk factors independent of body-mass-index (BMI). Previous GWAS on WHR adjusting for BMI (WHR’) have identified several SNPs but mainly among European descen