Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cheng-Chia Wu"'
Publikováno v:
Cardiology in Review. 22:1-12
20-Hydroxy-5, 8, 11, 14-eicosatetraenoic acid (20-HETE) is a cytochrome P450 (CYP)-derived omega-hydroxylation metabolite of arachidonic acid. 20-HETE has been shown to play a complex role in blood pressure regulation. In the kidney tubules, 20-HETE
Autor:
Shaojun Mei, Cheng-Chia Wu, Katherine H. Gotlinger, Jennifer Cheng, Victor Garcia, John R. Falck, Vijaya L. Manthati, Fan Zhang, Michal L. Schwartzman, Yan Ding, Adam Weidenhammer, Jorge H. Capdevila
Publikováno v:
Journal of the American Society of Nephrology. 24:1288-1296
Although the mechanism underlying the effect of androgen on BP and cardiovascular disease is not well understood, recent studies suggest that 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE), a primary cytochrome P450 4 (Cyp4)-derived eicosanoid,
Autor:
Cheng-Chia Wu, John R. Falck, Krutanjali Thakar, Yan Ding, Errabelli Ramu, Michal L. Schwartzman, Jennifer Cheng, Victor Garcia
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:1917-1924
Objective— 20-hydroxyeicosatetraenoic acid (20-HETE) promotes endothelial dysfunction by uncoupling endothelial NO synthase, stimulating O 2 − production, and reducing NO bioavailability. Moreover, 20-HETE–dependent vascular dysfunction and hyp
Autor:
Jawahar L. Jat, Frank Zhang, Michal L. Schwartzman, John R. Falck, Yilun Zhang, Cheng-Chia Wu, Mukul Kelkar, Katherine H. Gotlinger, Jennifer Cheng
Publikováno v:
Hypertension. 57:788-794
Increased vascular synthesis of 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE) is associated with increased vascular contraction, endothelial dysfunction, and endothelial activation; all are believed to account for 20-HETE prohypertensive prope
Publikováno v:
Hypertension. 60
20-Hydroxyeicosatetraenoic acid (20-HETE) is a cytochrome P450-derived arachidonic acid metabolite endowed with vasoconstrictor. Recent reports documented that 20-HETE synthesis inhibitors decrease the growth of glioma and renal cell carcimona, and t
Autor:
Yan Ding, Cheng-Chia Wu, Victor Garcia, Irina Dimitrova, Adam Weidenhammer, Frank Zhang, John R Falck, Shaojun Mei, Jorge Capdevila, Michal L Schwartzman
Publikováno v:
Hypertension. 60
20-Hydroxyeicosatetraenoic acid (20-HETE) promotes smooth muscle contraction and proliferation, endothelial dysfunction and activation and hypertension. We have previously demonstrated that 20-HETE mediates androgen-induced hypertension. This study e
Autor:
Victor Garcia, Jennifer Cheng, Yan Ding, Cheng-Chia Wu, John R Falck, Ramu Errabelli, Michal L Schwartzman
Publikováno v:
Hypertension. 60
20-hydroxyeicosatetraenoic acid (20-HETE), a cytochrome P450 derived arachidonic acid metabolite, is manufactured in the microcirculation and shown to sensitize the smooth muscle to constrictor stimuli and cause endothelial activation and dysfunction