Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Barbara McKnight"'
Autor:
Meng Wang, Zeneng Wang, Yujin Lee, Heidi T.M. Lai, Marcia C. de Oliveira Otto, Rozenn N. Lemaitre, Amanda Fretts, Nona Sotoodehnia, Matthew Budoff, Joseph A. DiDonato, Barbara McKnight, W.H. Wilson Tang, Bruce M. Psaty, David S. Siscovick, Stanley L. Hazen, Dariush Mozaffarian
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background:Effects of animal source foods (ASF) on atherosclerotic cardiovascular disease (ASCVD) and underlying mechanisms remain controversial. We investigated prospective associations of different ASF with incident ASCVD and potential mediation by
Autor:
Suraj Dahal, Peilin Shi, Meng Wang, Will Longstreth, Heidi Lai, Rozenn Lemaitre, David S Siscovick, Barbara McKnight, Amanda M Fretts, Marcia D Otto, Nona Sotoodehnia, W. H. Wilson Tang, Stanley L Hazen, Dariush Mozaffarian, Matthew J Budoff
Publikováno v:
Circulation. 144
Introduction: Findings on MRI of vascular brain injury, such as brain infarcts and white matter hyperintensities, are chronic manifestation of atherosclerosis. A gut-microbiome-generated metabolite, trimethylamine N-oxide (TMAO), is an independent pr
Autor:
Lin Y. Chen, Bruce M. Psaty, Susan R. Heckbert, Elsayed Z. Soliman, Barbara McKnight, Faye L. Norby, Barbara N Harding, James S. Floyd
Publikováno v:
Circulation. 143
Purpose: High blood pressure (BP) is a well-known risk factor for atrial fibrillation (AF), but a single BP measurement may provide limited information about AF risk in older adults. We evaluated whether longitudinal measures of BP were associated wi
Autor:
Amanda M. Fretts, Paul N. Jensen, David S. Siscovick, Nona Sotoodehnia, Irena B. King, Andrew N. Hoofnagle, Colleen M. Sitlani, Barbara McKnight, Rozenn N. Lemaitre, Bruce M. Psaty
Publikováno v:
Circulation. 141
Introduction: Recent studies suggest that the type of saturated fatty acid bound to sphingolipids influences sphingolipid activity, and that associations of ceramides (Cer) and sphingomyelins (SM) with cardiovascular outcomes may differ by lipid spec
Autor:
Heidi Lai, Dariush Mozaffarian, Barbara McKnight, Xiaoling Song, Yujin Lee, Bruce M. Psaty, Irena B. King, Marcia C de Oliveira Otto, Jason H Y Wu, David S. Siscovick, Rozenn N. Lemaitre
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Synthesized fatty acids ( FA s) from de novo lipogenesis may affect cardiometabolic health, but longitudinal associations between serially measured de novo lipogenesis–related fatty acid biomarkers and mortality or cardiovascular disease
Autor:
Paul N. Jensen, Rozenn N. Lemaitre, Dariush Mozaffarian, Susan R. Heckbert, Andrew N. Hoofnagle, Nona Sotoodehnia, David S. Siscovick, Amanda M. Fretts, Bruce M. Psaty, Irena B. King, Barbara McKnight
Publikováno v:
Circulation: Heart Failure. 12
Background: Ceramides exhibit multiple biological activities that may influence the pathophysiology of heart failure. These activities may be influenced by the saturated fatty acid carried by the ceramide (Cer). However, the associations of different
Autor:
Jason H Y Wu, Rozenn N. Lemaitre, Marcia C de Oliveira Otto, David S. Siscovick, Evan L. Thacker, Barbara McKnight, Dariush Mozaffarian, Irena B. King, Oscar L. Lopez, Xiaoling Song, Heidi Lai, Nikhil S. Padhye
Publikováno v:
Circulation. 139
Background: Polyunsaturated fatty acids (PUFA) are essential nutrients for normal brain function, constituting nearly 35% of brain lipids. Experimental studies suggest that omega-3 and omega-6 PUFA, present in plant foods and fish, may reduce risk of
Circulating Very Long‐Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study
Autor:
Xiaoling Song, Dariush Mozaffarian, Waqas Qureshi, David S. Siscovick, Barbara McKnight, Nona Sotoodehnia, Rozenn N. Lemaitre, Colleen M. Sitlani, Bruce M. Psaty, Irena B. King, Amanda M. Fretts
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Circulating very‐long‐chain saturated fatty acids ( VLSFAs ) are integrated biomarkers of diet and metabolism that may point to new risk pathways and potential targets for heart failure ( HF ) prevention. The associations of VLSFA to H
Autor:
Mariza de Andrade, Nicholas L. Smith, Kenneth Rice, James S. Pankow, Cathy C. Laurie, Amanda A. Seyerle, Charles Kooperberg, Cecelia A. Laurie, Brandon J. Coombes, Weihong Tang, Barbara McKnight, Tamar Sofer
Publikováno v:
Circulation. 137
Background: The Trans-Omics for Precision Medicine (TOPMed) program is performing whole-genome sequencing across multiple studies, including longitudinal cohorts, case-control, and case-only sample sets. Detecting the effects of low frequency variant
Autor:
Heidi T Lai, Marcia C de Oliveira Otto, Jason H Wu, Yujin Lee, Xiaoling Song, Irena B King, Bruce M Psaty, Rozenn N Lemaitre, Barbara McKnight, David S Siscovick, Dariush Mozaffarian
Publikováno v:
Circulation. 137
De novo lipogenesis (DNL) is a crucial metabolic pathway that convert excess carbohydrates to fatty acids (FA) for energy and storage. Both DNL and the synthesized FA have biologic effects that may affect cardiometabolic risk. Yet, the association be