Zobrazeno 81 - 90
of 4 625
pro vyhledávání: ''
Autor:
Gang Hui Lee, Po Ku Chen, Cheng Hsiang Kuo, Hua Lin Wu, Yi Hsun Huang, Ming Jer Tang, Guey Yueh Shi, Edward M. Conway
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41:1657-1671
Objective: VEGF (vascular endothelial growth factor) plays a critical role in physiological and pathological angiogenesis. Endothelial 3D podosomes (3DPs) are a type of F-actin-rich membrane microdomain, predominantly found in endothelial tip cells c
Publikováno v:
Pancreas. 50:756-765
Objectives This study aimed to investigate the effect and mechanism of hypoxia on pancreatic cancer (PC) cell dedifferentiation and tumorigenic potential. Methods Inhibition of hypoxia-inducible factor 1α (HIF-1α) and overexpression of Notch1 in PC
Autor:
Antonella Barreca, Emilio Hirsch, Gennaro Salvidio, Dario Roccatello, Marilena Durazzo, Beatrice Corbetta, Valentina Audrito, Roberto Gambino, Alessandro Corbelli, Stefania Bruno, Stefania Bellini, Shunsuke Kimura, Giovanni Camussi, Gabriella Gruden, Fabio Fiordaliso, Hiroshi Ohno, Mauro Papotti, Koji Hase, Miriam Martini, Silvia Deaglio, Gian Marco Ghiggeri, Federica Barutta
Publikováno v:
J Am Soc Nephrol
Background Podocyte dysfunction and loss are major determinants in the development of proteinuria. FSGS is one of the most common causes of proteinuria, but the mechanisms leading to podocyte injury or conferring protection against FSGS remain poorly
Autor:
Gertrud Lund, Silvio Zaina
Publikováno v:
Current Opinion in Lipidology. 32:389-391
Autor:
Gissette Reyes-Soffer
Publikováno v:
Curr Opin Lipidol
PURPOSE OF REVIEW: Lipoprotein(a) is a plasma circulating apoB100 (apoB) containing lipoprotein. It has a unique glycoprotein bound to the apoB100, apolipoprotein (a) [apo(a)]. The majority of the population expresses two apo(a) isoforms, when bound
Autor:
Sonette Steczina, Jennifer Davis, Charles E. Murry, Darrian Bugg, Amy M. Martinson, Kevin M. Beussman, Danny El-Nachef, Nathan J. Sniadecki
Publikováno v:
Circulation
Autor:
Robert C. Bauer, Krista Y. Hu
Publikováno v:
Curr Opin Lipidol
PURPOSE OF REVIEW The pseudokinase Tribbles-1 (TRIB1) remains the focus of intense research since genome-wide association studies (GWAS) associated it with multiple cardiometabolic traits in humans, including plasma lipids and atherosclerosis. This r
Autor:
Gangarao Davuluri, Maradumane L. Mohan, George R. Stark, Rebecca L. McCullough, Samjhana Thapaliya, Srinivasan Dasarathy, Laura E. Nagy, Megan R. McMullen, Sathyamangla V. Naga Prasad, Jinendiran Sekar, Mahesha Gangadhariah, Nicole Welch, McKenzie Stine, Sashi Kant, Avinash Kumar, Khaled Alsabbagh Alchirazi
Publikováno v:
Hepatology
BACKGROUND AND AIMS Despite the high clinical significance of sarcopenia in alcohol-associated cirrhosis, there are currently no effective therapies because the underlying mechanisms are poorly understood. We determined the mechanisms of ethanol-indu
Publikováno v:
Current Opinion in Lipidology. 32:183-190
Purpose of review Sodium-glucose cotransporter 2 (SGLT2) inhibitors are widely used antihyperglycemic drugs that show remarkable cardiorenal protective effects in patients with or without type 2 diabetes. Furthermore, they are effective among patient
Autor:
David L Hare
Publikováno v:
Current Opinion in Lipidology. 32:167-174
PURPOSE OF REVIEW: The purpose of this review is to outline the relationship between cardiovascular disease (CVD) and depression, both as a cause of and a result of CVD. RECENT FINDINGS: The prevalence of depression seems to be increasing in the gene