Zobrazeno 1 - 10
of 167
pro vyhledávání: ''
Publikováno v:
Current Opinion in Lipidology. 33:39-46
PURPOSE OF REVIEW Over the last two decades, evolving discoveries around angiopoietin-like (ANGPTL) proteins, particularly ANGPTL3, ANGPTL4, and ANGPTL8, have generated significant interest in understanding their roles in fatty acid (FA) metabolism.
Publikováno v:
Current Opinion in Lipidology. 30:370-376
Purpose of review In this review, we describe novel findings related to intestinal lipid transport in lymphatic vessels. Recent findings Studies have shown that chylomicron entry to lacteals and lymph movement in intestinal lymphatic capillaries is a
Autor:
Jaume Amengual, Tessa J. Barrett
Publikováno v:
Curr Opin Lipidol
Purpose of review Monocytes and macrophages are key players in the pathogenesis of atherosclerosis and dictate atherogenesis growth and stability. The heterogeneous nature of myeloid cells concerning their metabolic and phenotypic function is increas
Autor:
Oliver Soehnlein, Carla Winter
Publikováno v:
Current Opinion in Lipidology. 29:368-374
Purpose of review Development of atherosclerosis contributes to cardiovascular diseases that still are the leading cause of mortality worldwide. Successful strategies for treating inflammatory aspects of atherosclerotic lesion development are rare. H
Publikováno v:
Current Opinion in Lipidology. 29:240-245
Purpose of review Hematopoietic stem cells (HSCs) reside in the bone marrow and are important in replenishing all cells in the blood through a process termed hematopoiesis. One of the defining characteristics of HSCs is that they must be able to bala
Autor:
Hanrui Zhang
Publikováno v:
Current Opinion in Lipidology. 29:218-223
PURPOSE OF REVIEW: Lysosomal acid lipase (LAL), encoded by the LIPA gene, is an essential lysosomal enzyme that hydrolyzes cholesteryl ester and triglyceride delivered to the lysosome. This review highlights the novel pathophysiological role of LAL,
Autor:
Stefanie M. Novak, Pak Kin Wong, Cathleen Cover, Anne A. Wang, Daniela C. Zarnescu, Carol C. Gregorio, Elizabeth Juneman, Miensheng Chu, Ikeotunye Royal Chinyere
Publikováno v:
Circulation. 137:605-618
Background: Gap junction remodeling is well established as a consistent feature of human heart disease involving spontaneous ventricular arrhythmia. The mechanisms responsible for gap junction remodeling that include alterations in the distribution o
Autor:
Anish G. R. Potty, R. Justin Mistovich, Craig Cady, Nicola Maffulli, Hugo C. Rodriguez, Anne-Marie Fauser, Ashim Gupta
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9364, p 9364 (2020)
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9364, p 9364 (2020)
Stem cells for regenerative medicine purposes offer therapeutic benefits, but disadvantages are still ill defined. The benefit of stem cells may be attributed to their secretion of growth factors (GFs), cytokines (CKs), and extracellular vesicles (EV
Autor:
Sushil Kumar, Amanda Flockton, Angela Caánovas, Karim C. El Kasmi, Soni Savai Pullamsetti, Natalie J. Serkova, Maria G. Frid, Qinghong Zhang, B. Alexandre McKeon, Juan F. Medrano, Lydie Plecitá-Hlavatá, Mehdi A. Fini, Hongbing Liu, Dijana Iloska, Radu Moldovan, Suzette R. Riddle, Kurt R. Stenmark, Kirk C. Hansen, Min Li, Angelo D'Alessandro, Hui Zhang, Petr Ježek, Hong Li, Milton G Thomas
Publikováno v:
Circulation, vol 134, iss 15
Background: Changes in metabolism have been suggested to contribute to the aberrant phenotype of vascular wall cells, including fibroblasts, in pulmonary hypertension (PH). Here, we test the hypothesis that metabolic reprogramming to aerobic glycolys
Publikováno v:
Current Opinion in Lipidology
Purpose of review Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland. Numerous studies have suggested that melatonin plays an important role in various cardiovascular diseases. In this article, recent progress regarding m