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Publikováno v:
Current Opinion in Endocrinology, Diabetes & Obesity. 28:222-231
Purpose of review Enteroendocrine cells (EECs) are scattered chemosensory cells in the intestinal epithelium that release hormones with a wide range of actions on intestinal function, food intake and glucose homeostasis. The mechanisms by which gut h
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: TF (Tissue factor) plays a key role in hemostasis, but an aberrant expression of TF leads to thrombosis. The objective of the present study is to investigate the effect of 4-hydroxy-2-nonenal (HNE), the most stable and major oxidant produc
Publikováno v:
J Am Soc Nephrol
In the past few decades, sphingolipids and sphingolipid metabolites have gained attention because of their essential role in the pathogenesis and progression of kidney diseases. Studies in models of experimental and clinical nephropathies have descri
Publikováno v:
Current Opinion in Lipidology. 32:24-37
Purpose of review Ultra-processed foods (UPF) have been associated with poor diet quality and adverse health outcomes. Our aim in this review is to summarize recent research assessing the impact of UPF consumption, classified according to the NOVA sy
Publikováno v:
Current Opinion in Lipidology. 32:62-69
Purpose of review The aim of this study was to briefly summarize the contribution of the PREDIMED (PREvencion con DIeta MEDiterranea) trial on cardiovascular evidence and examine in depth its groundbreaking trajectory.PREDIMED was conducted during 20
Autor:
Gedaliah Farber, Liyong Zhang, Youan Liu, Dana J. Philpott, Fayez Dawood, Yena Oh, Kyoung-Han Kim, Alan Valaperti, Benjamin H. Rotstein, Peter P. Liu, Guo Hua Li, David Smyth, Mark Moon, Georges N. Kanaan, Wenbin Liang, Han-Bin Lin, Mary-Ellen Harper, Kotaro Naito
Publikováno v:
Circulation
Background: Cardiac hypertrophy is a key biological response to injurious stresses such as pressure overload and, when excessive, can lead to heart failure. Innate immune activation by danger signals, through intracellular pattern recognition recepto
Autor:
Susanna C. Larsson
Publikováno v:
Current Opinion in Lipidology. 32:1-8
PURPOSE OF REVIEW The current review describes the fundamentals of the Mendelian randomization framework and its current application for causal inference in human nutrition and metabolism. RECENT FINDINGS In the Mendelian randomization framework, gen
Autor:
Jeong-Min Kim, Eun-Kyung Jo, Yeongju Yeo, Eunhee S. Yi, Wonhee Suh, Koung Li Kim, Sang Gyu Park, S. J. Seo, Jong-Hyuk Sung, Ryul-I Kim
Publikováno v:
Hypertension. 76:1778-1786
Loss of BMP (bone morphogenic protein) signaling induces a phenotype switch of pulmonary arterial smooth muscle cells (PASMCs), which is the pathological basis of pulmonary vascular remodeling in pulmonary arterial hypertension (PAH). Here, we identi
Autor:
Dawn C. Schwenke
Publikováno v:
Current Opinion in Lipidology. 32:268-270
Publikováno v:
Current Opinion in Lipidology. 32:210-212