Zobrazeno 1 - 10
of 920
pro vyhledávání: ''
Autor:
Dinesh Kadariya, Salvatore Carbone, Hayley Billingsley, Richard H. Cooke, Antonio Abbate, Benjamin W. Van Tassell, Cory R. Trankle, Dave L. Dixon, Justin M. Canada, Linda Hart
Publikováno v:
J Cardiovasc Pharmacol
The sodium glucose co-transporter 2 inhibitors have demonstrated favorable effects on cardiovascular and renal disease; however, they may also increase low-density lipoprotein cholesterol (LDL-C). There are limited data directly comparing the effects
Autor:
Valentina Nardi, Amir Lerman, Kyra L. Jordan, Megha Prasad, Xiang Y. Zhu, Federico Franchi, Hui Tang, Morsaleh Ganji, Lilach O. Lerman, Melissa D. Young, Melanie C. Bois
Publikováno v:
Stroke. 52:2792-2801
Background and Purpose: XO (xanthine oxidase) is a key enzyme of uric acid metabolism and is thought to contribute to oxidative pathways that promote atherosclerotic plaque progression, yet its role in plaque destabilization is not well elucidated. W
Publikováno v:
Journal of Hypertension. 39:2395-2402
BACKGROUND A hypertensive response to exercise (HRE) is associated with cardiovascular disease and high blood pressure (BP). A poor cardiovascular risk factor profile may underlie these associations, although this has not been systematically elucidat
Autor:
Fan Xiaohang, Qiang Hao, Qinghua Hu, Shengquan Luo, Rui Xiao, Ting Zhang, Matthieu Ruiz, Xianqin Zeng, Ping Yuan, Tian Feng, Jin-Ming Liu, Jian-Guo He, Liping Zhu, Fangbo Liu, Zeshuai Chen, Jocelyn Dupuis, Mengxiang Sun
Publikováno v:
Circulation. 143:1775-1792
Background: The mevalonate pathway generates endogenous cholesterol and intermediates including geranylgeranyl pyrophosphate (GGPP). By reducing GGPP production, statins exert pleiotropic or cholesterol-independent effects. The potential regulation o
17‐Beta Hydroxysteroid Dehydrogenase 13 Deficiency Does Not Protect Mice From Obesogenic Diet Injury
Autor:
Bin Gao, Joselyn N. Allen, Natalia Y. Kedishvili, Philip M. Brown, Dennis D. Lin, Maren C. Podszun, Regina Umarova, Dechun Feng, Olga V. Belyaeva, Yanling Ma, Jason Roszik, David E. Kleiner, Oksana Gavrilova, Yaron Rotman, Jing Ma
Publikováno v:
Hepatology
Background and aims 17-Beta hydroxysteroid dehydrogenase 13 (HSD17B13) is genetically associated with human nonalcoholic fatty liver disease (NAFLD). Inactivating mutations in HSD17B13 protect humans from NAFLD-associated and alcohol-associated liver
Autor:
Do Hoon Kim, Jin-Hyung Jung, Kyu Na Lee, Yong Gyu Park, Joo-Hyun Park, Myung Ji Nam, Chung-Woo Lee, Kyungdo Han, Do Young Kwon, Ji Won Yoo, Hyun Jin Kim
Publikováno v:
Neurology. 96:e1391-e1401
ObjectiveTo investigate the longitudinal association among high-density lipoprotein cholesterol (HDL-C) level, HDL-C variability, and the risk of developing Parkinson disease (PD).MethodsWe conducted a nationwide, population-based cohort study. We in
Autor:
Sam E. Moussa, Juan P. Frias, Stephen A. Harrison, Kevin McCarty, Mustafa R. Bashir, Naim Alkhouri, Rebecca Taub
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 573-588 (2021)
Hepatology Communications
Hepatology Communications
Resmetirom (MGL‐3196), a selective thyroid hormone receptor‐β agonist, was evaluated in a 36‐week paired liver biopsy study ({"type":"clinical-trial","attrs":{"text":"NCT02912260","term_id":"NCT02912260"}}NCT02912260) in adults with biopsy‐c
Autor:
Wayne M. Clark, Paige Bergstrom, Phillip A. Wilmarth, Deanna L. Plubell, Sergio Fazio, Sara Rosario, Neil A. Zakai, Nathalie Pamir, Alex M. Fenton, Nabil J. Alkayed, Jessica Minnier, Joseph F. Quinn
Publikováno v:
Circ Res
Rationale: Prospective cohort studies question the value of HDL-C (high-density lipoprotein cholesterol) for stroke risk prediction. Objective: Investigate the relationship between long-term functional recovery and HDL proteome and function. Methods
Autor:
Nina Karamanova, Andrew F. Ducruet, Raymond Q. Migrino, Seth Truran, Volkmar Weissig, Maria Lozoya, Hannah Emerson, Saif Ahmad, Daniel R. Griffiths, Tyler Vail, Adam Kindelin, Jonathan Lifshitz
Publikováno v:
Stroke. 53
Background and Purpose: Neuroprotective strategies for stroke remain inadequate. Nanoliposomes comprised of phosphatidylcholine, cholesterol, and monosialogangliosides (nanoliposomes) induced an antioxidant protective response in endothelial cells ex
Publikováno v:
Circulation