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Autor:
Daniel E. Bassi, Jonathan M. Cenna, Edna Cukierman, Andres J. Klein-Szanto, Jirong Zhang, Samuel Litwin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 7, Pp 516-526 (2010)
PACE4 is a proprotein convertase (PC) responsible for cleaving and activating proteins that contribute to enhance tumor progression. PACE4 overexpression significantly increased the susceptibility to carcinogenesis, leading to enhanced tumor cell pro