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pro vyhledávání: ''
Autor:
Nanna Skeltved, Mads Daugaard, Maj Sofie Ørum-Madsen, Thomas Mandel Clausen, Mie A. Nordmaj, Swati Choudhary, Zhang Yang, Robert Dagil, Kaare V. Grunddal, Emilie S. Sachse, Thor G. Theander, Weihua Tian, Ali Salanti, Morten Nielsen, Igor Moskalev, Sayit Mahmut Erdoğan, Morgan E. Roberts, Anne Poder Andersen, Tobias Gustsavsson
Publikováno v:
Cell Death & Disease
Nordmaj, M A, Roberts, M E, Sachse, E S, Dagil, R, Andersen, A P, Skeltved, N, Grunddal, K V, Erdoğan, S M, Choudhary, S, Gustavsson, T, Ørum-madsen, M S, Moskalev, I, Tian, W, Yang, Z, Clausen, T M, Theander, T G, Daugaard, M, Nielsen, M A & Salanti, A 2021, ' Development of a bispecific immune engager using a recombinant malaria protein ', Cell Death & Disease, vol. 12, no. 4, 353 . https://doi.org/10.1038/s41419-021-03611-0
Cell Death and Disease, Vol 12, Iss 4, Pp 1-11 (2021)
Nordmaj, M A, Roberts, M E, Sachse, E S, Dagil, R, Andersen, A P, Skeltved, N, Grunddal, K V, Erdoğan, S M, Choudhary, S, Gustavsson, T, Ørum-madsen, M S, Moskalev, I, Tian, W, Yang, Z, Clausen, T M, Theander, T G, Daugaard, M, Nielsen, M A & Salanti, A 2021, ' Development of a bispecific immune engager using a recombinant malaria protein ', Cell Death & Disease, vol. 12, no. 4, 353 . https://doi.org/10.1038/s41419-021-03611-0
Cell Death and Disease, Vol 12, Iss 4, Pp 1-11 (2021)
As an immune evasion and survival strategy, the Plasmodium falciparum malaria parasite has evolved a protein named VAR2CSA. This protein mediates sequestration of infected red blood cells in the placenta through the interaction with a unique carbohyd
Autor:
Shao-Hao Chen, Hai Cai, Ning Xu, Fei Lin, Xiao-Dong Li, Jun-Ming Zhu, Ye-Hui Chen, Yong Wei, Yu-Peng Wu, Zhi-Bin Ke, Qing-Shui Zheng, Wen-Cai Zheng, Xue-Yi Xue
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Expression of kinesin family member 18B (KIF18B), an ATPase with key roles in cell division, is deregulated in many cancers, but its involvement in prostate cancer (PCa) is unclear. Here, we investigated the expression and function of KIF18B in human
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Chemotherapeutic agents have been linked to immunogenic cell death (ICD) induction that is capable of augmenting anti-tumor immune surveillance. The cardiac glycoside oleandrin, which inhibits Na+/K+-ATPase pump (NKP), has been shown to suppress brea
Autor:
Seong Dong Jeong, Hyeon Ho Kim, Hong-Hee Won, Mi-So Park, Woo Joo Lee, Dimitrios Tsitsipatis, Poonam R. Pandey, Myriam Gorospe, Chang Hoon Shin, Haein Ji
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-18 (2021)
Cell Death and Disease, Vol 12, Iss 4, Pp 1-18 (2021)
Malignant characteristics of cancers, represented by rapid cell proliferation and high metastatic potential, are a major cause of high cancer-related mortality. As a multifunctional RNA-binding protein, heterogeneous nuclear ribonucleoprotein K (hnRN
Autor:
Kajal Rajput, Animesh Kar, Ravi Datta Sharma, Dipankar Malakar, Gagan Dev, Trishna Pani, Rituparna Basak, Nihal Medatwal, S.V.S. Deo, Tushar Kanti Maiti, Ujjaini Dasgupta, Arnab Mukhopadhyay, Aneeshkumar G. Arimbasseri, Sharwan Kumar, Siddhi Gupta, Harsh Sharma, S. Saha, Avinash Bajaj
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 2, Pp 1-22 (2021)
Cell Death and Disease, Vol 12, Iss 2, Pp 1-22 (2021)
Global dysregulation of RNA splicing and imbalanced sphingolipid metabolism has emerged as promoters of cancer cell transformation. Here, we present specific signature of alternative splicing (AS) events of sphingolipid genes for each breast cancer s
Autor:
Wenqi Zhang, Lei Jiang, Xiaohui Xu, Wenjing Sun, Lifang Luo, Yi-Hu Zheng, Daoquan Fang, Weijian Zhu, Tan Hooi Min Grahn, Shuhan Li
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 2, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 2, Pp 1-13 (2021)
Cisplatin is one of the most effective chemotherapy drugs and is widely used in the treatment of cancer, including hepatocellular carcinoma (HCC) and cervical cancer, but its therapeutic benefit is limited by the development of resistance. Our previo
Autor:
Kathleen M. Attwood, Michel Roberge, Lauren P Westhaver, Inhwa Kim, David M. Brandman, Aaron Robichaud, Patricia Colp, Jennifer A. Corcoran, Aruna D. Balgi, Craig McCormick, Elizabeth L. Castle, Sidney E Croul, Adrienne Weeks
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 11, Pp 1-18 (2020)
Cell Death and Disease, Vol 11, Iss 11, Pp 1-18 (2020)
Glioblastoma (GBM) is the most common primary malignant brain tumor, and it has a uniformly poor prognosis. Hypoxia is a feature of the GBM microenvironment, and previous work has shown that cancer cells residing in hypoxic regions resist treatment.
Autor:
Linchen Wang, Danrui Cui, Longyuan Gong, Xiaoqing Dai, Xiaoyu Chen, Yongchao Zhao, Xiufang Xiong
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 11, Pp 1-13 (2020)
Cell Death and Disease, Vol 11, Iss 11, Pp 1-13 (2020)
DEP-domain containing mTOR-interacting protein (DEPTOR), a natural mTOR inhibitor, has essential roles in several processes, including cell growth, metabolism, apoptosis, and immunity. DEPTOR expression has been shown to be diversely controlled at tr
Autor:
Qian Liu, Yongzhong Hou, Huihui Xu, Qian Gou, Bibimaryam Khan, Chen Dong, Jianhua Jin, Juanjuan Shi
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 11, Pp 1-7 (2020)
Cell Death and Disease, Vol 11, Iss 11, Pp 1-7 (2020)
Programmed death ligand 1 (PD-L1, CD274) is an essential immune checkpoint protein that binds to programmed death 1 (PD-1) on T-lymphocytes. T cell plays a critical role in killing cancer cells while the cancer cell exhibits immune escape by the expr
Autor:
Zhihua Yang, Xiong Shu, Hui-Wen Zhang, Ting Yang, Yuliang Ran, Jun Liu, Long Yu, Lichao Sun, Lixin Sun
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 10, Pp 1-13 (2020)
Cell Death and Disease, Vol 11, Iss 10, Pp 1-13 (2020)
Background: Recent studies have demonstrated that gastric cancer stem cells (CSCs) are a rare sub-group of gastric cancer (GC) cells and play an important role in promoting the tumor growth and progression of GC. In the present study, we demonstrated