Zobrazeno 1 - 10
of 18
pro vyhledávání: ''
Autor:
Umberto Vitolo, Alessandra Rossi, Pier Luigi Zinzani, Claudio Agostinelli, Pier Giuseppe Pelicci, Saveria Mazzara, Giovanna Motta, Valentina Tabanelli, Federica Melle, Myriam Alcalay, Corrado Tarella, Francesco Bertolini, Paolo Falvo, Stefano Fiori, Beatrice Casadei, Elena Baiardi, Stefano Pileri, Stefania Orecchioni, Enrico Derenzini, Angelica Calleri, Chiara Corsini
Publikováno v:
Leukemia
Standard chemotherapies for diffuse large B-cell lymphoma (DLBCL), based on the induction of exogenous DNA damage and oxidative stress, are often less effective in the presence of increased MYC and BCL-2 levels, especially in the case of double hit (
Autor:
Natalia Voronina, Aurélie Ernst, Marc Zapatka, Gino Cioffi, Jill S. Barnholtz-Sloan, Andreas von Deimling, David T.W. Jones, Marina Ryzhova, Christian Aichmüller, Stefan M. Pfister, Thorsten Kolb, Andrey Korshunov, Martin Sill, Jan Gronych, Jonas Frisén
Publikováno v:
Oncogene
Adult pilocytic astrocytomas (PAs) have been regarded as indistinguishable from pediatric PAs in terms of genome-wide expression and methylation patterns. It has been unclear whether adult PAs arise early in life and remain asymptomatic until adultho
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
The CXC chemokine receptor 4 (CXCR4) exerts a variety of functions at different steps of hepatocellular carcinoma (HCC) progression. The molecular mechanisms and therapeutic value of CXCR4 in the development of HCC remain undefined. Here we show that
Publikováno v:
British Journal of Cancer
Background Combinations of inflammatory markers are used as prognostic scores in cancer patients with cachexia. We investigated whether they could also be used to prioritise patients attending primary care with unexpected weight loss for cancer inves
Autor:
Derong Xie, Won Seog Kim, Yuan Zhu, Xin Du, Ting Liu, Junxin Wu, Tao Wu, Pingyong Yi, Yanming Deng, Xiangyuan Wu, Gang Wu, Xiaoyan Ke, Huangming Hong, Jie Jin, Ye Guo, Wei-Li Zhao, Kangsheng Gu, Fanyi Meng, Mingzhi Zhang, Zhigang Peng, Jinghua Wang, Jun Zhu, Tongyu Lin, Daren Lin, Chaoyong Liang, Qing Liu, He Huang, Juan Li, Soon Thye Lim, Yexiong Li
Publikováno v:
Leukemia
Autor:
Kasper Adelborg, Dóra Körmendiné Farkas, Mads Okkels Birk Lorenzen, Henrik Toft Sørensen, Jens Sundbøll
Publikováno v:
British Journal of Cancer
Lorenzen, M O B, Farkas, D K, Adelborg, K, Sundbøll, J & Sørensen, H T 2020, ' Syncope as a sign of occult cancers : a population-based cohort study ', British Journal of Cancer, vol. 122, no. 4, pp. 595-600 . https://doi.org/10.1038/s41416-019-0692-2
Lorenzen, M O B, Farkas, D K, Adelborg, K, Sundbøll, J & Sørensen, H T 2020, ' Syncope as a sign of occult cancers : a population-based cohort study ', British Journal of Cancer, vol. 122, no. 4, pp. 595-600 . https://doi.org/10.1038/s41416-019-0692-2
Background We examined if syncope was a marker of an occult cancer by comparing the risk in patients with a syncope episode with that of the general population. Methods Using Danish population-based medical registries, we identified all patients diag
Autor:
Sum-Yin Chan, To-Wai Leung, Chi-Chung Tong, Ka-On Lam, John M. Nicholls, Sik-Kwan Chan, Victor Ho-Fun Lee, Mai-Yee Luk, Ka-Chun Tsang, Dora L.W. Kwong, Cheuk-Wai Choi, Anne Wing-Mui Lee, Tsz-Him So, Pek-Lan Khong
Publikováno v:
British Journal of Cancer
Background Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) in endemic regions may have undetectable plasma EBV DNA. Methods We prospectively recruited 518 patients with non-metastatic NPC and measured their pre-treatment plasma EBV
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Glioblastoma multiforme (GBM) is the most frequent type of primary astrocytomas. We examined the association between single nucleotide polymorphisms (SNPs) in Aurora kinase A (AURKA), Aurora kinase B (AURKB), Aurora kinase C (AURKC) and Polo-like kin
Autor:
Buwen Yao, Xiaolin Ji, Jiang-feng You, Fang Mei, Rui Wu, Xinyang Li, Fei Pei, Yan Liu, Mengxue Zhang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
The screening of non-small cell lung cancer (NSCLC) tumors for anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements is important because of the dramatically favorable therapy response to ALK inhibitor. However, the exact mechanism o
Autor:
Norikatsu Miyoshi, Masayuki Ohue, Shiki Fujino, Mamoru Uemura, Aya Ito, Tsunekazu Mizushima, Masayoshi Yasui, Chu Matsuda, Yuichiro Doki, Hidetoshi Eguchi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
POU5F1-expressing cells can self-renew and differentiate, contributing to metastasis formation in colorectal cancer (CRC), but it plays an important role in normal pluripotent stem cells. Here, we identified the CRC-specific gene, HNF1A, which is the