Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jose R. Conejo-Garcia"'
Autor:
Yu Cao, Shikhar Mehrotra, Eslam Mohamed, David H. Munn, Anthony M. Magliocco, Ling Cen, Rosa A. Sierra, Jose R. Conejo-Garcia, Richard Klar, Carmen M. Anadon, Sven Michel, Juan R. Cubillos-Ruiz, Wenjie Dai, Jimena Trillo-Tinoco, Paulo C. Rodriguez, Douglas C. Marchion, Frank Jaschinski, Richard R. Reich, Tara Lee Costich
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
Understanding the intrinsic mediators that render CD8+ T cells dysfunctional in the tumor microenvironment is a requirement to develop more effective cancer immunotherapies. Here, we report that C/EBP homologous protein (Chop), a downstream sensor of
Autor:
David H. Munn, Wenjie Dai, Rosa A. Sierra, Carmen M. Anadon, Jimena Trillo-Tinoco, Shikhar Mehrotra, Frank Jaschinski, Richard Klar, Sven Michel, Eslam Mohamed, Yu Cao, Jose R. Conejo-Garcia, Ling Cen, Paulo C. Rodriguez, Juan R. Cubillos-Ruiz, Douglas C. Marchion, Anthony M. Magliocco, Richard R. Reich, Tara Lee Costich
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Alvaro Padron, Srilakshmi Pandeswara, Ratna K. Vadlamudi, Vincent Hurez, Bin Yuan, Rong Li, Curtis A. Clark, Jose R. Conejo-Garcia, Harshita Gupta, Gangadhara R. Sareddy, Tyler J. Curiel
Publikováno v:
Signal Transduction and Targeted Therapy
As tumor PD-L1 provides signals to anti-tumor PD-1+ T cells that blunt their functions, αPD-1 and αPD-L1 antibodies have been developed as anti-cancer immunotherapies based on interrupting this signaling axis. However, tumor cell-intrinsic PD-L1 si