Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Falzon M."'
Autor:
Frankell, A.M., Dietzen, M., Al Bakir, M., Lim, E.L., Karasaki, T., Ward, S., Veeriah, S., Colliver, E., Huebner, A., Bunkum, A., Hill, M.S., Grigoriadis, K., Moore, D.A., Black, J.R.M., Liu, W.K., Thol, K., Pich, O., Watkins, T.B.K., Naceur-Lombardelli, C., Cook, D.E., Salgado, R., Wilson, G.A., Bailey, C., Angelova, M., Bentham, R., Martínez-Ruiz, C., Abbosh, C., Nicholson, A.G., Le Quesne, J., Biswas, D., Rosenthal, R., Puttick, C., Hessey, S., Lee, C., Prymas, P., Toncheva, A., Smith, J., Xing, W., Nicod, J., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Blyth, K.G., Fennell, D.A., Forster, M.D., Lee, S.M., Falzon, M., Hewish, M., Shackcloth, M.J., Lim, E., Benafif, S., Russell, P., Boleti, E., Krebs, M.G., Lester, J.F., Papadatos-Pastos, D., Ahmad, T., Thakrar, R.M., Lawrence, D., Navani, N., Janes, S.M., Dive, C., Blackhall, F.H, Summers, Y., Cave, J., Marafioti, T., Herrero, J., Quezada, S.A., Peggs, K.S., Schwarz, R.F., Van Loo, P., Miedema, D.M., Birkbak, N.J., Hiley, C.T., Hackshaw, A., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N., Swanton, C.
Lung cancer is the leading cause of cancer-associated mortality worldwide. Here we analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients with non-small cell lung cancer prospectively enrolled into the TRACER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=mdc______med::ef45f584564f3d0f221808d502071a8b
http://edoc.mdc-berlin.de/23266/5/23266suppl.zip
http://edoc.mdc-berlin.de/23266/5/23266suppl.zip
Autor:
Abbosh, C, Birkbak, NJ, Wilson, GA, Jamal-Hanjani, M, Constantin, T, Salari, R, Quesne, JL, Moore, DA, Veeriah, S, Rosenthal, R, Marafioti, T, Kirkizlar, E, Watkins, TBK, McGranahan, N, Ward, S, Martinson, L, Riley, J, Fraioli, F, Bakir, MA, GrÖnroos, E, Zambrana, F, Endozo, R, Bi, WL, Fennessy, FM, Sponer, N, Johnson, D, Laycock, J, Shafi, S, Czyzewska-Khan, J, Rowan, A, Chambers, T, Matthews, N, Turajlic, S, Hiley, C, Lee, SM, Forster, MD, Ahmad, T, Falzon, M, Borg, E, Lawrence, D, Hayward, M, Kolvekar, S, Panagiotopoulos, N, Janes, SM, Thakrar, R, Ahmed, A, Blackhall, F, Summers, Y, Hafez, D, Naik, A, Ganguly, A, Kareht, S, Shah, R, Joseph, L, Quinn, AM, Crosbie, P, Naidu, B, Middleton, G, Langman, G, Trotter, S, Nicolson, M, Remmen, H, Kerr, K, Chetty, M, Gomersall, L, Fennell, DA, Nakas, A, Rathinam, S, Anand, G, Khan, S, Russell, P, Ezhil, V, Ismail, B, Irvin-sellers, M, Prakash, V, Lester, JF, Kornaszewska, M, Attanoos, R, Adams, H, Davies, H, Oukrif, D, Akarca, AU, Hartley, JA, Lowe, HL, Lock, S, Iles, N, Bell, H, Ngai, Y, Elgar, G, Szallasi, Z, Schwarz, RF, Herrero, J, Stewart, A, Quezada, SA, Van Loo, P, Dive, C, Lin, CJ, Rabinowitz, M, Aerts, HJWL, Hackshaw, A, Shaw, JA, Zimmermann, BG, Swanton, C, Bosshard-Carter, L, Goh, G, Gorman, P, Murugaesu, N, Hynds, RE, Wilson, G, Horswell, S, Al Bakir, M, Mitter, R, Escudero, M, Xu, H, Goldman, J, Stone, RK, Denner, T, Biggs, J, Costa, M, Begum, S, Phillimore, B, Nye, E, Graca, S, Joshi, K, Furness, A, Aissa, AB, Wong, YNS, Georgiou, A, Quezada, S, Simeon, C, Hector, G, Smith, A, Aranda, M, Novelli, M, Forster, M, Papadatos-Pastos, D, Carnell, D, Mendes, R, George, J, Navani, N, Taylor, M, Choudhary, J, Califano, R, Taylor, P, Krysiak, P, Rammohan, K, Fontaine, E, Booton, R, Evison, M, Moss, S, Idries, F, Bishop, P, Chaturved, A, Marie Quinn, A, Doran, H, leek, A, Harrison, P, Moore, K, Waddington, R, Novasio, J, Rogan, J, Smith, E, Tugwood, J, Brady, G, Rothwell, DG, Chemi, F, Pierce, J, Gulati, S, Bellamy, M, Bancroft, H, Kerr, A, Kadiri, S, Webb, J, Djearaman, M, Fennell, D, Le Quesne, J, Moore, D, Thomas, A, Walter, H, Monteiro, W, Marshall, H, Nelson, L, Bennett, J, Primrose, L, Amadi, A, Palmer, S, Miller, J, Buchan, K, Lester, J, Edwards, A, Morgan, F, Verjee, A, MacKenzie, M, Wilcox, M, Smith, S, Gower, N, Ottensmeier, C, Chee, S, Johnson, B, Alzetani, A, Shaw, E, Lim, E, De Sousa, P, Tavares Barbosa, M, Bowman, A, Jordan, S, Rice, A, Raubenheimer, H, Proli, C, Elena Cufari, M, Ronquillo, JC, Kwayie, A, Bhayani, H, Hamilton, M, Bakar, Y, Mensah, N, Ambrose, L, Devaraj, A, Buderi, S, Finch, J, Azcarate, L, Chavan, H, Green, S, Mashinga, H, Nicholson, AG, Lau, K, Sheaff, M, Schmid, P, Conibear, J, Light, T, Horey, T, Danson, S, Bury, J, Edwards, J, Hill, J, Matthews, S, Kitsanta, Y, Suvarna, K, Fisher, P, Keerio, AD, Shackcloth, M, Gosney, J, Postmus, P, Feeney, S, Asante-Siaw, J, Constatin, T, Zimmermann, B, Dentro, S, Dessimoz, C, Shiu, K-K, Bridgewater, J, Hochauser, D, Beck, S, Parker, P, Walczak, H, Enver, T, Proctor, I, Sinclair, R, Lok, C-W, Mitchison, M, Trevisan, G, Lynch, M, Brandner, S, Gishen, F, Tookman, A, Stone, P, Sterling, C, Larkin, J, Attard, G, Eeles, R, Foster, C, Bova, S, Sottoriva, A, Chowdhury, S, Ashish, C, Spicer, J, Stares, M, Lynch, J, Caldas, C, Brenton, J, Fitzgerald, R, Jimenez-Linan, M, Provenzano, E, Cluroe, A, Stewart, G, Watts, C, Gilbertson, R, McDermott, U, Tavare, S, Maughan, T, Tomlinson, I, Campbell, P, McNeish, I, Biankin, A, Chambers, A, Fraser, S, Oien, K, Krebs, M, Marais, R, Carter, L, Nonaka, D, Dhomen, N, Shaw, J, Baijal, S, Tanchel, B, Collard, M, Cockcroft, P, Taylor, J, Colloby, P, Olisemeke, B, Wilson, R, Harrison, D, Loda, M, Flanagan, A, McKenzie, M, Lederman, J, Sharp, A, Farrelly, L
Publikováno v:
Nature, vol. 545, no. 7655, pp. 446-451
The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed metastatic sites, might offer new therapeutic approaches for limiting tumour recurrence. The ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488928e0797fc6a75de4915f82e9cf29
https://orca.cardiff.ac.uk/id/eprint/100264/1/nature22364.pdf
https://orca.cardiff.ac.uk/id/eprint/100264/1/nature22364.pdf
Autor:
Pinder, S. E., Campbell, Amy, Bartlett, J. M. S., Marshall, A. (Andrea), Allen, D., Falzon, M., Dunn, Janet A., Makris, A., Hughes-Davies, L., Stein, R. C., HASH(0x5651c9d1a1b8)
Publikováno v:
British Journal of Cancer
Pinder, S, Campbell, A F, Bartlett, J M S, Marshall, A, Allen, D, Falzon, M, Dunn, J A, Makris, A, Hughes-Davies, L & Stein, R C 2017, ' Discrepancies in central review re-testing of patients with ER-positive and HER2-negative breast cancer in the OPTIMA prelim randomised clinical trial ', British Journal of Cancer, vol. 116, no. 7, pp. 859-863 . https://doi.org/10.1038/bjc.2017.28
Pinder, S, Campbell, A F, Bartlett, J M S, Marshall, A, Allen, D, Falzon, M, Dunn, J A, Makris, A, Hughes-Davies, L & Stein, R C 2017, ' Discrepancies in central review re-testing of patients with ER-positive and HER2-negative breast cancer in the OPTIMA prelim randomised clinical trial ', British Journal of Cancer, vol. 116, no. 7, pp. 859-863 . https://doi.org/10.1038/bjc.2017.28
Background:\ud There is limited data on results of central re-testing of samples from patients with invasive breast cancer categorised in their local hospital laboratories as oestrogen receptor (ER) positive and human epidermal growth factor receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df94221b3f80a81e744289dcd8847131
http://wrap.warwick.ac.uk/86436/7/WRAP-discrepancies-re-testing-ER-positive-HER2-negative-breast-cancer-OPTIMA-trial-Dunn-2017.pdf
http://wrap.warwick.ac.uk/86436/7/WRAP-discrepancies-re-testing-ER-positive-HER2-negative-breast-cancer-OPTIMA-trial-Dunn-2017.pdf
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Akademický článek
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Autor:
Abbosh, C, Birkbak, NJ, Wilson, GA, Jamal-Hanjani, M, Constantin, T, Salari, R, Le Quesne, J, Moore, DA, Veeriah, S, Rosenthal, R, Marafioti, T, Kirkizlar, E, Watkins, TBK, McGranahan, N, Ward, S, Martinson, L, Riley, J, Fraioli, F, Al Bakir, M, Grönroos, E, Zambrana, F, Endozo, R, Bi, WL, Fennessy, FM, Sponer, N, Johnson, D, Laycock, J, Shafi, S, Czyzewska-Khan, J, Rowan, A, Chambers, T, Matthews, N, Turajlic, S, Hiley, C, Lee, SM, Forster, MD, Ahmad, T, Falzon, M, Borg, E, Lawrence, D, Hayward, M, Kolvekar, S, Panagiotopoulos, N, Janes, SM, Thakrar, R, Ahmed, A, Blackhall, F, Summers, Y, Hafez, D, Naik, A, Ganguly, A, Kareht, S, Shah, R, Joseph, L, Marie Quinn, A, Crosbie, PA, Naidu, B, Middleton, G, Langman, G, Trotter, S, Nicolson, M, Remmen, H, Kerr, K, Chetty, M, Gomersall, L, Fennell, DA, Nakas, A, Rathinam, S, Anand, G, Khan, S, Russell, P, Ezhil, V, Ismail, B, Irvin-Sellers, M, Prakash, V, Lester, JF, Kornaszewska, M, Attanoos, R, Adams, H, Davies, H, Oukrif, D, Akarca, AU, Hartley, JA, Lowe, HL, Lock, S, Iles, N, Bell, H, Ngai, Y, Elgar, G, Szallasi, Z, Schwarz, RF, Herrero, J, Stewart, A, Quezada, SA, Peggs, KS, Van Loo, P, Dive, C, Lin, CJ, Rabinowitz, M, Aerts, HJWL, Hackshaw, A, Shaw, JA, Zimmermann, BG, TRACERx Consortium, PEACE Consortium, Swanton, C
The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed metastatic sites, might offer new therapeutic approaches for limiting tumour recurrence. The ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41d01a170bd1c4e5fbb46ddc108ac90c
Autor:
Frankell AM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Dietzen M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Lim EL; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Karasaki T; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK., Ward S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Bunkum A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Grigoriadis K; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Moore DA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK., Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Liu WK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK., Thol K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Bailey C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Angelova M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Bentham R; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Nicholson AG; Department of Histopathology, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Le Quesne J; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Pathology Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK., Biswas D; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK., Rosenthal R; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Puttick C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Hessey S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Lee C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Division of Medicine, University College London, London, UK., Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Smith J; Scientific Computing, The Francis Crick Institute, London, UK., Xing W; Scientific Computing, The Francis Crick Institute, London, UK., Nicod J; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Price G; Department of Medical Oncology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; University of Aberdeen, Aberdeen, UK., Kerr KM; University of Aberdeen, Aberdeen, UK.; Department of Pathology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK., Naidu B; Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK., Middleton G; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Blyth KG; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Queen Elizabeth University Hospital, Glasgow, UK., Fennell DA; University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK., Forster MD; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK., Lee SM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK., Falzon M; Department of Cellular Pathology, University College London Hospitals, London, UK., Hewish M; Royal Surrey Hospital, Royal Surrey Hospitals NHS Foundation Trust, Guilford, UK.; University of Surrey, Guilford, UK., Shackcloth MJ; Liverpool Heart and Chest Hospital, Liverpool, UK., Lim E; Academic Division of Thoracic Surgery, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK., Benafif S; Department of Oncology, University College London Hospitals, London, UK., Russell P; Princess Alexandra Hospital, The Princess Alexandra Hospital NHS Trust, Harlow, UK., Boleti E; Royal Free Hospital, Royal Free London NHS Foundation Trust, London, UK., Krebs MG; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Lester JF; Singleton Hospital, Swansea Bay University Health Board, Swansea, UK., Papadatos-Pastos D; Department of Oncology, University College London Hospitals, London, UK., Ahmad T; Department of Oncology, University College London Hospitals, London, UK., Thakrar RM; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Lawrence D; Department of Thoracic Surgery, University College London Hospital NHS Trust, London, UK., Navani N; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Janes SM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Dive C; Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University of Manchester, Manchester, UK., Blackhall FH; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Summers Y; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Cave J; Department of Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Marafioti T; Department of Cellular Pathology, University College London Hospitals, London, UK., Herrero J; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK., Quezada SA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK., Peggs KS; Department of Haematology, University College London Hospitals, London, UK.; Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK., Schwarz RF; Institute for Computational Cancer Biology, Center for Integrated Oncology (CIO), Cancer Research Center Cologne Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Berlin Institute for the Foundations of Learning and Data (BIFOLD), Berlin, Germany., Van Loo P; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK., Miedema DM; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Amsterdam, The Netherlands., Birkbak NJ; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Hackshaw A; Cancer Research UK and UCL Cancer Trials Centre, London, UK., Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. m.jamal-hanjani@ucl.ac.uk., McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk., Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. charles.swanton@crick.ac.uk.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. charles.swanton@crick.ac.uk.
Publikováno v:
Nature [Nature] 2024 Jul; Vol. 631 (8022), pp. E15.
Autor:
Al Bakir M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Grigoriadis K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK., Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Laycock J; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Johnson D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Rowan A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Razaq M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Akther M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Hessey S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Dietzen M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Bunkum A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK., Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Hiley CT; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Nye E; Experimental Histopathology, The Francis Crick Institute, London, UK., Stone RK; Experimental Histopathology, The Francis Crick Institute, London, UK., Fennell DA; University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK., Price G; Department of Medical Oncology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; University of Aberdeen, Aberdeen, UK., Kerr KM; University of Aberdeen, Aberdeen, UK.; Department of Pathology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK., Naidu B; Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Middleton G; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Summers Y; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Lindsay CR; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Blackhall FH; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Cave J; Department of Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Blyth KG; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK.; Queen Elizabeth University Hospital, Glasgow, UK., Nair A; Department of Radiology, University College London Hospitals, London, UK.; UCL Respiratory, Department of Medicine, University College London, London, UK., Ahmed A; Department of Radiology, University College London Hospitals, London, UK., Taylor MN; Department of Radiology, University College London Hospitals, London, UK., Procter AJ; Department of Radiology, University College London Hospitals, London, UK., Falzon M; Department of Cellular Pathology, University College London Hospitals, London, UK., Lawrence D; Department of Thoracic Surgery, University College London Hospital NHS Trust, London, UK., Navani N; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Department of Thoracic Medicine, University College London Hospitals, London, UK., Thakrar RM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Department of Thoracic Medicine, University College London Hospitals, London, UK., Janes SM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Papadatos-Pastos D; Department of Oncology, University College London Hospitals, London, UK., Forster MD; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK., Lee SM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK., Ahmad T; Department of Oncology, University College London Hospitals, London, UK., Quezada SA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK., Peggs KS; Department of Haematology, University College London Hospitals, London, UK.; Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK., Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Dive C; Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University of Manchester, Manchester, UK., Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK., Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. m.jamal-hanjani@ucl.ac.uk., McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk., Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. Charles.Swanton@crick.ac.uk.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. Charles.Swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. Charles.Swanton@crick.ac.uk.
Publikováno v:
Nature [Nature] 2023 Apr; Vol. 616 (7957), pp. 534-542. Date of Electronic Publication: 2023 Apr 12.
Autor:
Frankell AM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Dietzen M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Lim EL; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Karasaki T; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK., Ward S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Bunkum A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Grigoriadis K; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Moore DA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK., Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Liu WK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK., Thol K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Bailey C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Angelova M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Bentham R; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Nicholson AG; Department of Histopathology, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Le Quesne J; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Pathology Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK., Biswas D; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK., Rosenthal R; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK., Puttick C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Hessey S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Lee C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Division of Medicine, University College London, London, UK., Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Smith J; Scientific Computing, The Francis Crick Institute, London, UK., Xing W; Scientific Computing, The Francis Crick Institute, London, UK., Nicod J; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Price G; Department of Medical Oncology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; University of Aberdeen, Aberdeen, UK., Kerr KM; University of Aberdeen, Aberdeen, UK.; Department of Pathology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK., Naidu B; Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK., Middleton G; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Blyth KG; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Queen Elizabeth University Hospital, Glasgow, UK., Fennell DA; University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK., Forster MD; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK., Lee SM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK., Falzon M; Department of Cellular Pathology, University College London Hospitals, London, UK., Hewish M; Royal Surrey Hospital, Royal Surrey Hospitals NHS Foundation Trust, Guilford, UK.; University of Surrey, Guilford, UK., Shackcloth MJ; Liverpool Heart and Chest Hospital, Liverpool, UK., Lim E; Academic Division of Thoracic Surgery, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK., Benafif S; Department of Oncology, University College London Hospitals, London, UK., Russell P; Princess Alexandra Hospital, The Princess Alexandra Hospital NHS Trust, Harlow, UK., Boleti E; Royal Free Hospital, Royal Free London NHS Foundation Trust, London, UK., Krebs MG; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Lester JF; Singleton Hospital, Swansea Bay University Health Board, Swansea, UK., Papadatos-Pastos D; Department of Oncology, University College London Hospitals, London, UK., Ahmad T; Department of Oncology, University College London Hospitals, London, UK., Thakrar RM; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Lawrence D; Department of Thoracic Surgery, University College London Hospital NHS Trust, London, UK., Navani N; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Janes SM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Dive C; Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University of Manchester, Manchester, UK., Blackhall FH; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Summers Y; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK., Cave J; Department of Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Marafioti T; Department of Cellular Pathology, University College London Hospitals, London, UK., Herrero J; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK., Quezada SA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK., Peggs KS; Department of Haematology, University College London Hospitals, London, UK.; Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK., Schwarz RF; Institute for Computational Cancer Biology, Center for Integrated Oncology (CIO), Cancer Research Center Cologne Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Berlin Institute for the Foundations of Learning and Data (BIFOLD), Berlin, Germany., Van Loo P; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK., Miedema DM; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Amsterdam, The Netherlands., Birkbak NJ; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Hackshaw A; Cancer Research UK and UCL Cancer Trials Centre, London, UK., Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK., Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. m.jamal-hanjani@ucl.ac.uk., McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk., Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. charles.swanton@crick.ac.uk.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. charles.swanton@crick.ac.uk.
Publikováno v:
Nature [Nature] 2023 Apr; Vol. 616 (7957), pp. 525-533. Date of Electronic Publication: 2023 Apr 12.
Autor:
Abbosh C, Birkbak NJ, Wilson GA, Jamal-Hanjani M, Constantin T, Salari R, Le Quesne J, Moore DA, Veeriah S, Rosenthal R, Marafioti T, Kirkizlar E, Watkins TBK, McGranahan N, Ward S, Martinson L, Riley J, Fraioli F, Al Bakir M, Grönroos E, Zambrana F, Endozo R, Bi WL, Fennessy FM, Sponer N, Johnson D, Laycock J, Shafi S, Czyzewska-Khan J, Rowan A, Chambers T, Matthews N, Turajlic S, Hiley C, Lee SM, Forster MD, Ahmad T, Falzon M, Borg E, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Hafez D, Naik A, Ganguly A, Kareht S, Shah R, Joseph L, Quinn AM, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Oukrif D, Akarca AU, Hartley JA, Lowe HL, Lock S, Iles N, Bell H, Ngai Y, Elgar G, Szallasi Z, Schwarz RF, Herrero J, Stewart A, Quezada SA, Peggs KS, Van Loo P, Dive C, Lin CJ, Rabinowitz M, Aerts HJWL, Hackshaw A, Shaw JA, Zimmermann BG, Swanton C
Publikováno v:
Nature [Nature] 2018 Feb 08; Vol. 554 (7691), pp. 264. Date of Electronic Publication: 2017 Dec 20.