Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fang Chen"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
PTEN is frequently mutated in prostate cancer. The tumor suppressor function of PTEN is attributed to its lipid phosphatase activity that counters PI3K action. Here, we report a PTEN-ARID4B-PI3K axis in which PTEN inhibits expression of ARID4B, while
Autor:
Ruoh-Fang Yen, Jiann-Shing Jeng, Bo Ching Lee, Sung-Chun Tang, Hsin-Hsi Tsai, Li-Kai Tsai, Ya-Fang Chen
Publikováno v:
Scientific Reports
The underlying pathology of cerebral microbleeds (CMBs) with mixed lobar and deep distribution remains contentious. The aim of this study was to correlate CMBs distribution to β-amyloid burden in patients with primary intracerebral hemorrhage (ICH).
Publikováno v:
Scientific Reports
Small-airway remodelling is one of the most remarkable pathological features of chronic obstructive pulmonary disease (COPD), in which angiogenesis plays a critical role that contributes to disease progression. The endothelial cell-specific mitogen v
Autor:
Zilong Qiu, Chen Dong, Xiao Li, Sheng-Nan Xia, Cheng Cheng, Yinqi Shao, Wenhao Zhou, Ran Zhang, Jingjing Zhou, Bo Yuan, Bin Yu, Dali Tong, Xiuya Yu, Jingwen Lyu, Zhi-Fang Chen
Publikováno v:
Scientific Reports
Duplications of Methyl CpG binding protein 2 (MECP2) -containing segments lead to the MECP2 duplication syndrome, in which severe autistic symptoms were identified. Whether adult neurogenesis may play a role in pathogenesis of autism and the role of
Autor:
Xiong Zhang, Song-Fang Chen, Jian-Hong Zhu, Hui Zhu, Ting Li, Jian-Yong Wang, Qing-Qing Zhuang, Chen-Ping Huang, Lan-Bing Zhu, Rui Li
Publikováno v:
Scientific Reports
Brain iron levels in patients of Parkinson’s disease (PD) are usually measured in postmortem samples or by MRI imaging including R2* and SWI. In this study we performed a meta-analysis to understand PD-associated iron changes in various brain regio
Autor:
Fang Chen, Patrik Andersson, Hideki Iwamoto, Yunlong Yang, Guohui Nie, Sharon Lim, Takahiro Seki, Yin Zhang, Yongtian Lu, Renhai Cao, Xiaoyun Chen, Masaki Nakamura, Yihai Cao, Peter Vilhelm Skov, Kayoko Hosaka, Mitsuhiko Abe, Carina Fischer
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Yang, Y, Zhang, Y, Iwamoto, H, Hosaka, K, Seki, T, Andersson, P, Lim, S, Fischer, C, Nakamura, M, Abe, M, Skov, P V, Feng, C, Chen, X, Lu, Y, Nie, G & Cao, Y 2016, ' Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism ', Nature Communications, vol. 7, 12680 . https://doi.org/10.1038/ncomms12680
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Yang, Y, Zhang, Y, Iwamoto, H, Hosaka, K, Seki, T, Andersson, P, Lim, S, Fischer, C, Nakamura, M, Abe, M, Skov, P V, Feng, C, Chen, X, Lu, Y, Nie, G & Cao, Y 2016, ' Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism ', Nature Communications, vol. 7, 12680 . https://doi.org/10.1038/ncomms12680
The impact of discontinuation of anti-VEGF cancer therapy in promoting cancer metastasis is unknown. Here we show discontinuation of anti-VEGF treatment creates a time-window of profound structural changes of liver sinusoidal vasculatures, exhibiting