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Autor:
Jiao Li, Shaoheng Li, Liping Liu, Hee-Do Hong, Qinggao Zhang, Yong Yang, Shuo Yuan, Xiaoyu Tan, Yuying Cao
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Aging is an irreversible process. This research aims to study the anti-aging effects of GRCP, a compound preparation made by Ganoderma lucidum and Rhodiola rosen, in aging rats. Rats were subcutaneously injected with 400 mg/kg of d-galactose daily, a
Autor:
Hu, Yuanyuan, Cronan, John E.
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Pimelic acid, a seven carbon α,ω-dicarboxylic acid (heptanedioic acid), is known to provide seven of the ten biotin carbon atoms including all those of the valeryl side chain. Distinct pimelate synthesis pathways were recently elucidated in Escheri
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Epithelia are an eminent tissue type and a common driver of tumorigenesis, requiring continual precision in cell division to maintain tissue structure and genome integrity. Mitotic defects often trigger apoptosis, impairing cell viability as a tradeo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Herpes simplex virus type-1 (HSV-1), one of the most widely spread human viruses in the Herpesviridae family, causes herpes labialis (cold sores) and keratitis (inflammation of the cornea). Conventional treatment for HSV-1 infection includes pharmace
Autor:
Liu Shaona, Bin Zhang, Baoyu Jia, De-Cai Xiang, Guoquan Wu, Qionghua Hong, Shao Qingyong, Guobo Quan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Mammalian oocytes represent impaired quality after undergoing a process of postovulatory aging, which can be alleviated through various effective ways such as reagent treatment. Accumulating evidences have revealed the beneficial effects of astaxanth
Autor:
Patrick J. Rochette, Anne-Sophie Gary
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Ultraviolet radiation (UVR) is a major environmental genotoxic agent. In skin, it can lead to the formation of mutagenic DNA damage. Several mechanisms are in place to prevent the conversion of these DNA damage into skin cancer-driver mutations. An i
Extended-spectrum β-lactamase-producing Escherichia coli isolated from raw vegetables in South Korea
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
The increasing prevalence of oxyimino-cephalosporin-resistant Enterobacteriaceae has become a global concern because of their clinical impact on both human and veterinary medicine. The present study determined the prevalence, antimicrobial susceptibi
Autor:
Ping Yan, Quanen Deng, Jianan Li, Chao Gao, Dezhi Jiang, Junyong Cheng, Xianzhen Deng, Liang Li
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
To assess the adaptability of Camellia oleifera for introduction in new growth locations, this study evaluated 10 representative C. oleifera cultivars from the main areas in China where this oil-producing evergreen crop is grown. Cluster analysis, co
Autor:
Risako Nakano, Aisha Yesbolatova, Yumiko Saga, Kosuke Fukui, Yuichiro Saito, Ken-ichiro Hayashi, Hirofumi Nakaoka, Kanae Gamo, Rieko Ajima, Naomi Kitamoto, Yusuke Tominari, Hatsune Makino-Itou, Masato T. Kanemaki, Haruki Takeuchi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Protein knockdown using the auxin-inducible degron (AID) technology is useful to study protein function in living cells because it induces rapid depletion, which makes it possible to observe an immediate phenotype. However, the current AID system has
Autor:
Toshikatsu Kaburaki, Akihisa Kato, Yasushi Kawaguchi, Yoshihiro Urade, Atsuko Miki, Kenzui Taniue, Kentaro Kawata, Hidetoshi Kawashima, Rena Onoguchi-Mizutani, Shintaro Shirahama, Makoto Aihara, Nobuyoshi Akimitsu, Rie Tanaka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Long non-coding RNAs (lncRNAs) play vital roles in the pathogenesis of infectious diseases, but the role of lncRNAs in herpes simplex virus 1 (HSV-1) infection remains unknown. Using RNA sequencing analysis, we explored lncRNAs that were highly expre