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Autor:
F. Stephen Laroux, Bradford L. McRae, Wallace Craig, Jamie Erickson, Stephanie M. Gaudette, Christopher Stedman, Christine M. Nelson, Gricelda H. Simler, Samuel D. Karsen, Annette J. Schwartz Sterman, Rajesh V. Kamath, Liang Zhang, Marc Wurbel, Soumya Mitra, Calvin S. Pohl, Ruoqi Peng
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Intestinal permeability and neutrophil activity are closely linked to inflammatory bowel disease (IBD) pathophysiology. Here we discuss two techniques for assessing permeability and neutrophil activity in mouse IBD models using near infrared (NIR) de
Autor:
Sungwoo Chei, Young-Jin Seo, Kippeum Lee, Boo-Yong Lee, Hyun-Ji Oh, Ji-Hyeon Song, Kui-Jin Kim
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The blue-green alga Spirulina maxima is a microscopic filamentous cyanobacterium. Spirulina was recently reported to elicit beneficial effects such as reducing cholesterol and inducing weight loss; however, its effects on inflammation are unknown. To
Autor:
Knut Mai, Matthias B. Schulze, Ronald Biemann, Cornelia Weikert, Alessa Longree, Berend Isermann, Juliane Menzel, Klaus Abraham
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Vegetarian or vegan nutrition might influence inflammatory processes, thereby reducing the risk of chronic diseases. As the vegan diet becomes more importance in modern societies, data from the “Risks and Benefits of a Vegan Diet”-study has been
Autor:
Takeaki Osu, Kiyoshi Takeda, Hisako Kayama, Mamoru Uemura, Shiki Fujino, Hiroshi Matsuno, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Cheryl-Emiliane T. Chow, Yuki Sekido, Hiroki Ikeuchi, Kazuhiro Nakano, Junichi Nishimura, Yuichiro Doki, Masaki Mori, Chu Matsuda, Motoi Uchino, Tsunekazu Mizushima
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Crohn’s disease causes chronic inflammation in the gastrointestinal tract and its pathogenesis remains unclear. In the intestine of Crohn’s disease patients, CD14+CD11+CD163low macrophages contribute to inflammation through the induction of Th17
Autor:
Ling Huang, Jingnan Xu, Jianxin Chen, Xueyan Ma, Chen Bai, Xiaohong Gu, Tiegang Liu, Shaoyang Liu, He Yu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Intestinal flora plays an important role in inflammatory response to systemic or local organs of its host. High calorie diet has been shown to aggravate the condition of pneumonia and delay recovery, especially in children. However, the underlying me
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Platelet-rich fibrin (PRF) provides a scaffold for cell migration and growth factors for promoting wound healing and tissue regeneration. Here, we report using PRF in periodontal healing after open flap debridement (OFD) in canine periodontitis. A sp
Autor:
Tristan R. McKay, Julien Baruteau, Jonathan D. Cooper, Rajvinder Karda, John R. Counsell, Els Henckaerts, Juan Antinao Diaz, Ahad A. Rahim, Simon N. Waddington, Dany P. Perocheau, Nuria Palomar Martin, Maha Tijani, Andrew Wong, Michael P. Hughes, Joanne Ng, Juliette M. K. M. Delhove, Suzanne M. K. Buckley, Natalie Suff
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Karda, R, Rahim, A A, Wong, A M S, Suff, N, Diaz, J A, Perocheau, D P, Tijani, M, Ng, J, Baruteau, J, Martin, N P, Hughes, M, Delhove, J M K M, Counsell, J R, Cooper, J D, Henckaerts, E, Mckay, T R, Buckley, S M K & Waddington, S N 2020, ' Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors ', Scientific Reports, vol. 10, no. 1, 2121 . https://doi.org/10.1038/s41598-020-59075-3
Scientific Reports
Karda, R, Rahim, A A, Wong, A M S, Suff, N, Diaz, J A, Perocheau, D P, Tijani, M, Ng, J, Baruteau, J, Martin, N P, Hughes, M, Delhove, J M K M, Counsell, J R, Cooper, J D, Henckaerts, E, Mckay, T R, Buckley, S M K & Waddington, S N 2020, ' Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors ', Scientific Reports, vol. 10, no. 1, 2121 . https://doi.org/10.1038/s41598-020-59075-3
We have previously designed a library of lentiviral vectors to generate somatic-transgenic rodents to monitor signalling pathways in diseased organs using whole-body bioluminescence imaging, in conscious, freely moving rodents. We have now expanded t
Autor:
Mousavi, Soraya, Escher, Ulrike, Thunhorst, Elisa, Kittler, Sophie, Kehrenberg, Corinna, Bereswill, Stefan, Heimesaat, Markus M.
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Human foodborne infections with the zoonotic pathogen Campylobacter jejuni are on the rise and constitute a significant socioeconomic burden worldwide. The health-beneficial, particularly anti-inflammatory effects of vitamin C (ascorbate) are well kn
Autor:
Aldrin V. Gomes, Brett S. Phinney, Joanne L. Newens, Michelle Salemi, Shuchita Tiwari, Manish Mishra
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
Ibuprofen, an inhibitor of prostanoid biosynthesis, is a common pharmacological agent used for the management of pain, inflammation and fever. However, the chronic use of ibuprofen at high doses is associated with increased risk for cardiovascular, r
Autor:
Jana, Hesse-Macabata, Bianka, Morgner, Peter, Elsner, Uta-Christina, Hipler, Cornelia, Wiegand
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Exceedingly virulent pathogens and growing antimicrobial resistances require new therapeutic approaches. The zoophilic dermatophyte Trichophyton benhamiae causes highly inflammatory, cutaneous fungal infections. Recently, it could be shown that the p