Zobrazeno 101 - 110
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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Inflammatory bowel disease (IBD) is an immunological disease associated with CD4+ T cell activation in the intestines. CD81 is a regulator of the immune system with multiple biological functions. Therefore, in this study, we assessed the contribution
Autor:
Ralf Ludwig, Peter König, Mario Pieper, Katja Bieber, Rebecca Pfündl, Detlef Zillikens, Jennifer E. Hundt, Hiroaki Iwata
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
In several autoimmune diseases, e.g., pemphigoid disease (PD), autoantibodies are the direct cause of pathology. Albeit key requirements for antibody-mediated diseases were identified, their interactions and exact temporal and spatial interactions re
Autor:
S. J. Van Schyndel, J. F. W. Sprícigo, M.R. Carvalho, O. Bogado Pascottini, Stephen J. LeBlanc, B. Mion, Eduardo S. Ribeiro
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Systemic inflammation (SI) is increasingly studied in several species because it may be central in many metabolic disturbances and be a risk factor for clinical disease. This proof-of-concept study evaluated the effects of the anti-inflammatory drug
Autor:
Yukinori Tanaka, Reiska Kumala Bakti, Shunji Sugawara, Gaku Ouchi, Kanan Bando, Toshinobu Kuroishi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Nickel (Ni) is the most frequent metal allergen and induces Th1-dependent type-IV allergies. In local skin, epidermal Langerhans cells (LCs) and/or dermal dendritic cells (DCs) uptake antigens and migrate to draining lymph nodes (LNs). However, the s
Autor:
Yuko Yoshikawa, Yuto Yoshikawa, Michio Sato, Takuji Suzuki, Yuta Tsunematsu, Misaki Uchikawa, Noriyuki Miyoshi, Akika Nagata, Shunsuke Sanada, Kenji Watanabe, Tsutomu Hashidume, Mai Kato
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
When the microfloral composition deteriorates, it triggers low-level chronic inflammation associated with several lifestyle-related diseases including obesity and diabetic mellitus. Fecal volatile organic compounds (VOCs) have been found to differ in
Autor:
Yasser Bustanji, Shereen M. Aleidi, Ahmad T. Mansour, Eman Y. Abu-rish, Hebah T. Mansour, Lina A. Dahabiyeh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Immune system alteration has been implicated in the pathogenesis of chronic pain conditions, epilepsy and generalized anxiety disorder. Targeting cytokines has recently been proposed for the management of such conditions. Pregabalin (PGB) is an antie
Autor:
María Paz Villegas-Pérez, Alberto Triviño, Francisco J. Valiente-Soriano, Manuel Vidal-Sanz, José Ramírez, José A. Fernández‐Albarral, Blanca Rojas, Elena Salobrar-García, Juan J. Salazar, Ana I. Ramírez, Marcelino Avilés-Trigueros, Rosa de Hoz
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Microglial activation is associated with glaucoma. In the model of unilateral laser-induced ocular hypertension (OHT), the time point at which the inflammatory process peaks remains unknown. Different time points (1, 3, 5, 8, and 15 d) were compared
Autor:
Shannon N. Tessier, Daniel Irimia, Galit H. Frydman, Mehmet Toner, Keith H. K. Wong, Ronald G. Tompkins, James G. Fox, Charles R. Vanderburg
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Histones are typically located within the intracellular compartment, and more specifically, within the nucleus. When histones are located within the extracellular compartment, they change roles and become damage-associated molecular patterns (DAMPs),
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Exposure to chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) has been associated with allergic contact dermatitis and occupational asthma. Despite this association however, no study has investigated the effects of CMIT/MIT exposure on the
Autor:
Roberta De Godoy, Jayesh Dudhia, Mark E. Morrey, Mustafa S. Rashid, Andrew Carr, Stephanie G. Dakin, Pierre-Alexis Mouthuy, Sarah J. B. Snelling, Roger Smith
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
We investigated endogenous tissue response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch intended for tendon repair. A sheep tendon injury model characterised by a natural history of consistent failure of healing was