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Autor:
Clara Hammarström, Wojciech Pietka, Denis Khnykin, Manuela Zucknick, Olav Sundnes, Guttorm Haraldsen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Current studies addressing the influence of interleukin-33 or its receptor (IL-33R/ST2) on development of atopic dermatitis-like inflammation in mice have reported conflicting results. We compared the response in single- and double-deficient IL-33−
Autor:
Chieh Tseng, Ping Guo, Matthieu Huard, Ruth McCarrick-Walmsley, Kaitlyn E. Whitney, Johnny Huard, Christopher P. Allen, Liang Wang, Aiping Lu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Duchenne muscular dystrophy (DMD) is a progressive muscle disease, characterized by mutations in the X-linked dystrophin, that has several therapeutic options but no curative treatment. Transplantation of muscle progenitor cells for treatment of DMD
Autor:
Andrew V. Schally, Chongxu Zhang, Aaron Lazerson, Greg Holt, Michael Campos, Robert M. Jackson, Mehdi Mirsaeidi, Norman H. Altman, Stephanie Chery
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Lung inflammation due to sarcoidosis is characterized by a complex cascade of immunopathologic events, including leukocyte recruitment and granuloma formation. α-melanocyte stimulating hormone (α-MSH) is a melanocortin signaling peptide with anti-i
Autor:
Zachary Fouladian, Reuben H. Kim, Mo K. Kang, Kristina I. Boström, Terresa Kim, Jin Sook Suh, No-Hee Park, Aldons J. Lusis, Sung Hee Lee, Jae Young Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
Periodontitis is a local and systemic inflammatory condition and a risk factor of atherosclerosis, but no studies investigated the effect of a statin on atherogenesis affected by severe periodontitis. In this study, we investigated the effect of rosu
Autor:
Juçara Gastaldi Cominal, Natalia de Souza Nunes, Fabíola Attié de Castro, Maria Gabriela Berzoti-Coelho, Lúcia Helena Faccioli, Daniela Carlos, Lorena Lobo de Figueiredo-Pontes, Ítalo Sousa Pereira, Fabiani Gai Frantz, Maira da Costa Cacemiro, Raquel Tognon, Belinda Pinto Simões
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Polycythemia vera (PV) is a clonal disorder resulting from neoplastic transformation of hematopoietic stem cells, while secondary polycythemia (SP) is a disease characterized by increased absolute red blood cell mass caused by stimulation of red bloo
Autor:
Theron Hamilton, Faith C. Blum, Kenneth G. Frey, Mark G. Lewis, D. Scott Merrell, Joseph J. Mattapallil, Britney L. Hardy, Kimberly A. Bishop-Lilly, James B. Whitney
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Human immunodeficiency virus (HIV) infection is characterized by a massive loss of CD4 T cells in the gastrointestinal tract (GIT) that is accompanied by changes in the gut microbiome and microbial translocation that contribute to inflammation and ch
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Outcomes of cardiac surgery are influenced by systemic inflammation. High mobility group box 1 (HMGB1), a pivotal inflammatory mediator, plays a potential role as a prognostic biomarker in cardiovascular disease. The aim of this prospective, observat
Autor:
Rémy Froissart, Shaun L. Barnabas, Heather B. Jaspan, Linda G. Bekker, Shameem Z. Jaumdally, Hoyam Gamieldien, Glenda Gray, Jo-Ann S. Passmore, Andrea G. Abrahams, Lindi Masson, Monalisa T. Manhanzva, Smritee Dabee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Female genital tract (FGT) inflammation increases HIV infection susceptibility. Non-optimal cervicovaginal microbiota, characterized by depletion of Lactobacillus species and increased bacterial diversity, is associated with increased FGT cytokine pr
Autor:
Ritsumi Saito, Teiji Tominaga, Masayuki Yamamoto, Daisuke Saigusa, Takahiro Yamazaki, Yoshihisa Tomioka, Akira Uruno, Yotaro Matsumoto, Sherif Rashad, Kuniyasu Niizuma
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Understanding the root causes of neuronal vulnerability to ischemia is paramount to the development of new therapies for stroke. Transient global cerebral ischemia (tGCI) leads to selective neuronal cell death in the CA1 sub-region of the hippocampus
Autor:
Dietmar H. Pieper, Margarethe Smoczek, Manuela Buettner, Anja Siebert, Nils-Holger Zschemisch, Marius Vital, Marijana Basic, André Bleich, Dirk Wedekind
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific reports
England
Scientific Reports
Scientific reports
England
Scientific Reports
Obesity has emerged as a major global health problem and is associated with various diseases, such as metabolic syndrome, type 2 diabetes mellitus, and cardiovascular diseases. The inbred C57BL/6 mouse strain is often used for various experimental in