Zobrazeno 1 - 5
of 5
pro vyhledávání: ''
Autor:
Ruud van Winkel, Eugenia Kravariti, Matthias Weisbrod, Jim van Os, Bart P. F. Rutten, Lieuwe de Haan, Vaughan Bell, Behrooz Z. Alizadeh, Katja Schulze, Benedicto Crespo-Facorro, Claudia J. P. Simons, Jurjen J. Luykx, Assen Jablensky, Wiepke Cahn, Conrad Iyegbe, Frederike Schirmbeck, Elvira Bramon, John Powell, Jasmine Harju-Seppänen, Jeremy Hall, Rebecca M. Jones, René S. Kahn, Robin M. Murray, Luba Kalaydjieva, Dan Rujescu, Sonja M C de Zwarte, Marco Picchioni, Johan H. Thygesen, Roel A. Ophoff, Anjali Bhat, Therese van Amelsvoort, Timothea Toulopoulou, Siri Ranlund, Rebecca Muir, Kuang Lin, Diana Prata, Mei-Hua Hall, Ignacio Mata, Muriel Walshe, Stephen M. Lawrie, Karoline Kuchenbaecker, Madiha Shaikh, Eirini Zartaloudi, Isabelle Austin-Zimmerman, Evangelos Vassos, Richard Bruggeman, Agna A. Bartels-Velthuis, Andrew M. McIntosh, Haritz Irizar, Neeltje E.M. van Haren, Marta Di Forti, Andrew McQuillin, Alvaro Diez-Revuelta, Cathryn M. Lewis, Amelia Presman, Stella Calafato, Colm McDonald
Publikováno v:
Molecular Psychiatry, 26(9). Nature Publishing Group
Molecular psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry
Molecular Psychiatry, vol 26, iss 9
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Thygesen, J H, Presman, A, Harju-seppänen, J, Irizar, H, Jones, R, Kuchenbaecker, K, Lin, K, Alizadeh, B Z, Austin-zimmerman, I, Bartels-velthuis, A, Bhat, A, Bruggeman, R, Cahn, W, Calafato, S, Crespo-facorro, B, De Haan, L, De Zwarte, S M C, Di Forti, M, Díez-revuelta, Á, Hall, J, Hall, M, Iyegbe, C, Jablensky, A, Kahn, R, Kalaydjieva, L, Kravariti, E, Lawrie, S, Luykx, J J, Mata, I, Mcdonald, C, Mcintosh, A M, Mcquillin, A, Muir, R, Ophoff, R, Picchioni, M, Prata, D P, Ranlund, S, Rujescu, D, Rutten, B P F, Schulze, K, Shaikh, M, Schirmbeck, F, Simons, C J P, Toulopoulou, T, Van Amelsvoort, T, Van Haren, N, Van Os, J, Van Winkel, R, Vassos, E, Walshe, M, Weisbrod, M, Zartaloudi, E, Bell, V, Powell, J, Lewis, C M, Murray, R M & Bramon, E 2020, ' Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study ', Molecular Psychiatry . https://doi.org/10.1038/s41380-020-0820-7
Molecular psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry
Molecular Psychiatry, vol 26, iss 9
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Thygesen, J H, Presman, A, Harju-seppänen, J, Irizar, H, Jones, R, Kuchenbaecker, K, Lin, K, Alizadeh, B Z, Austin-zimmerman, I, Bartels-velthuis, A, Bhat, A, Bruggeman, R, Cahn, W, Calafato, S, Crespo-facorro, B, De Haan, L, De Zwarte, S M C, Di Forti, M, Díez-revuelta, Á, Hall, J, Hall, M, Iyegbe, C, Jablensky, A, Kahn, R, Kalaydjieva, L, Kravariti, E, Lawrie, S, Luykx, J J, Mata, I, Mcdonald, C, Mcintosh, A M, Mcquillin, A, Muir, R, Ophoff, R, Picchioni, M, Prata, D P, Ranlund, S, Rujescu, D, Rutten, B P F, Schulze, K, Shaikh, M, Schirmbeck, F, Simons, C J P, Toulopoulou, T, Van Amelsvoort, T, Van Haren, N, Van Os, J, Van Winkel, R, Vassos, E, Walshe, M, Weisbrod, M, Zartaloudi, E, Bell, V, Powell, J, Lewis, C M, Murray, R M & Bramon, E 2020, ' Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study ', Molecular Psychiatry . https://doi.org/10.1038/s41380-020-0820-7
The burden of large and rare copy number genetic variants (CNVs) as well as certain specific CNVs increase the risk of developing schizophrenia. Several cognitive measures are purported schizophrenia endophenotypes and may represent an intermediate p
Autor:
Dan Rujescu, Vidar M. Steen, Eva Krapohl, Aarno Palotie, Elisabeth Widen, Ingrid Melle, Patrick Sullivan, Katrina L. Grasby, Stephan Ripke, Anke R. Hammerschlag, Christiaan de Leeuw, Panos Bitsios, Nikos C. Stefanis, Tonya White, Gail Davies, Ahmad R. Hariri, Philip R. Jansen, Peter B. Barr, John M. Starr, Max Lam, Ian J. Deary, Sara Hägg, Dimitrios Avramopoulos, Bettina Konte, Anil K. Malhotra, Delilah Zabaneh, Kjetil Sundet, Tinca J. C. Polderman, Ornit Chiba-Falek, Jakob Kaminski, Danielle M. Dick, Andrea Christoforou, Jin Yu, Gunter Schumann, Matthew A. Scult, Anna C. Need, Jens Hjerling-Leffler, Gonçalo R. Abecasis, Kenneth S. Kendler, Todd Lencz, Dwight Dickinson, Bradley T. Webb, Elizabeth T. Cirulli, Stephanie Le Hellard, Gerome Breen, Astri J. Lundervold, Hannah Young, Erin Burke Quinlan, William Ollier, Nikolaos Smyrnis, Emily Drabant Conley, Danielle Posthuma, Sten Linnarsson, Aristotle N. Voineskos, Edythe D. London, Pamela DeRosse, Russell A. Poldrack, Jonathan R. I. Coleman, Jeanne E. Savage, Sarah E. Medland, Ana B. Muñoz-Manchado, Richard E. Straub, Robert Plomin, Ida K. Karlsson, Nathan G. Skene, Dan E. Arking, Birgit Debrabant, Joey W. Trampush, Matthew C. Keller, Mats Nagel, Gary Donohoe, Chandra A. Reynolds, Panos Roussos, Lene Christiansen, Ivar Reinvang, Ole A. Andreassen, Antony Payton, Robert Karlsson, Margaret J. Wright, Deborah C. Koltai, Jari Lahti, Andreas Heinz, Tyrone D. Cannon, Eliza Congdon, Olav B. Smeland, Stella G. Giakoumaki, Marianne Nygaard, Julien Bryois, M. Arfan Ikram, Nancy L. Pedersen, Katri Räikkönen, Daniel R. Weinberger, Neil Pendleton, Swapnil Awasthi, Sven Stringer, Nelson A. Freimer, Aiden Corvin, Kyoko Watanabe, David C. Glahn, Henning Tiemeier, Grant W. Montgomery, Narelle K. Hansell, Robert M. Bilder, Katherine E. Burdick, Srdjan Djurovic, David C. Liewald, Sophie van der Sluis, Thomas Espeseth, Scott I. Vrieze, Fred W. Sabb, Nicholas G. Martin, Michael Gill, Emma Knowles, Derek W. Morris, Alex Hatzimanolis, Ina Giegling, Johan G. Eriksson
Publikováno v:
Nature Genetics, 50(7), 912-+. Nature Publishing Group
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Nature Genetics, 50(7), 912-919. Nature Publishing Group
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, 0, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Christiansen, L & Debrabant, B 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912–919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Nature Genetics, 50(7), 912-919. Nature Publishing Group
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, 0, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Christiansen, L & Debrabant, B 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912–919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Intelligence is highly heritable 1 and a major determinant of human health and well-being 2 . Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in intelligence 3-7 , but much about its genetic underpinnings remains
Autor:
Rosalind A. Eeles, Karina Dalsgaard Sørensen, Torben F. Ørntoft, Jeri Kim, Wayne D. Tilley, Ruth C. Travis, Lorelei A. Mucci, Jenny L Donovan, Kay-Tee Khaw, Edward Giovannucci, Christopher I. Amos, Soo Hwang Teo, Claire Aukim-Hastie, Gerald L. Andriole, Linda Steele, Martin Eklund, Guomin Wang, Michael Borre, Antonio Finelli, Liesel M. FitzGerald, Thérèse Truong, Robert N. Hoover, Sandeep Singhal, Radka Kaneva, Frank Claessens, Robert Szulkin, Javier Llorca, Dominika Wokołorczyk, Esther M. John, Daniel J. Schaid, Jyotsna Batra, Kathryn L. Penney, Børge G. Nordestgaard, Catharine M L West, Hermann Brenner, Sue A. Ingles, Markus Aly, Jonathan Tyrer, Thomas J. Schnoeller, Xin Guo, Peter Iversen, Olivier Cussenot, Laurence N. Kolonel, Henrik Grönberg, Ninghan Feng, Geraldine Cancel-Tassin, Christiane Maier, David E. Neal, Marija Gamulin, Ezequiel Anokian, Christopher J. Logothetis, Shannon K. McDonnell, Lovise Maehle, Anssi Auvinen, Antonio Gómez-Caamaño, Tomislav Kuliš, Manuel Luedeke, Teuvo L.J. Tammela, Brian D. Carter, Zan Sun, Jong Y. Park, Nawaid Usmani, Ian M. Thompson, Zuxi Cui, Johanna Schleutker, Bernd Holleczek, Davor Lessel, Katarina Cuk, Eli Marie Grindedal, Milan S. Geybels, Yuan Chun Ding, Phyllis J. Goodman, Jing Ma, Paul A. Townsend, Edward J. Saunders, Melissa C. Southey, Graham G. Giles, Robert J. Hamilton, Laura Fachal, Mitchell J. Machiela, Demetrius Albanes, Gert De Meerleer, Paula Paulo, Agnieszka Michael, Yves Akoli Koudou, Janet L. Stanford, Kim De Ruyck, Thomas Van den Broeck, Tokhir Dadaev, Clara Cieza-Borrella, Sonja I. Berndt, Artitaya Lophatananon, Brian E. Henderson, Niclas Håkansson, Christopher A. Haiman, Florence Menegaux, Xueying Mao, Jan Lubinski, Elio Riboli, Paul D.P. Pharoah, David J. Hunter, Loic Le Marchand, Stephen N. Thibodeau, Fredrik Wiklund, Tobias Nordström, Thomas A. Sellers, Chee Goh, Elaine A. Ostrander, Sune F. Nielsen, Neil E. Fleshner, Neil G. Burnet, Rasmus Bisbjerg, Manuela Gago Dominguez, Csilla Sipeky, Maria Elena Martinez, Susan L. Neuhausen, Stephen J. Chanock, Hui Yi Lin, Laura E. Beane Freeman, A. Siddiq, Alicja Wolk, Gemma Castaño-Vinyals, Lisa F. Newcomb, Catherine M. Tangen, Ana Vega, Peter Kraft, Chavdar Slavov, Daniel Leongamornlert, Lisa A. Cannon-Albright, Stella Koutros, Manuel R. Teixeira, Susan M. Gapstur, Federico Canzian, Sara Lindström, Maren Weischer, Bettina F. Drake, Lisa G. Horvath, Daniel W. Lin, Jose Esteban Castelao, Yong-Jie Lu, Xin Sheng, Vanio Mitev, Ron H.N. van Schaik, Monique J. Roobol, Zsofia Kote-Jarai, Leire Moya, Alison M. Dunning, Mahbubl Ahmed, Kenneth Muir, Douglas F. Easton, Suzanne K. Chambers, Hongwei Zhang, Jianfeng Xu, Jasmine Lim, Meir J. Stampfer, Guido Jenster, Ali Amin Al Olama, Victoria L. Stevens, Sara Benlloch, Mark N. Brook, Azad Hassan Abdul Razack, Marta Cardoso, Matthew Parliament, Gail P. Risbridger, Samantha E.T. Larkin, Fredrick R. Schumacher, Martin Andreas Røder, Harry Ostrer, Judith A. Clements, Manolis Kogevinas, Barry S. Rosenstein, Steven Joniau, Richard M. Martin, Constance Turman, Mariana C. Stern, Joe Dennis, David V. Conti, Sarah L. Kerns, Adam S. Kibel, Robert J. MacInnis, Stephanie J. Weinstein, Freddie C. Hamdy, Cezary Cybulski, Nora Pashayan, Timothy J. Key, Hardev Pandha, Piet Ost
Publikováno v:
Schumacher, F R, Al Olama, A A, Berndt, S I, Benlloch, S, Ahmed, M, Saunders, E J, Dadaev, T, Leongamornlert, D, Anokian, E, Cieza-Borrella, C, Goh, C, Brook, M N, Sheng, X, Fachal, L, Dennis, J, Tyrer, J, Muir, K, Lophatananon, A, Stevens, V L, Gapstur, S M, Carter, B D, Tangen, C M, Goodman, P J, Thompson, I M, Batra, J, Chambers, S, Moya, L, Clements, J, Horvath, L, Tilley, W, Risbridger, G P, Gronberg, H, Aly, M, Nordström, T, Pharoah, P, Pashayan, N, Schleutker, J, Tammela, T L J, Sipeky, C, Auvinen, A, Albanes, D, Weinstein, S, Wolk, A, Sorensen, K D, Orntoft, T F, Borre, M & Profile Study 2018, ' Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci ', Nature Genetics, vol. 50, no. 7, pp. 928-936 . https://doi.org/10.1038/s41588-018-0142-8
the Profile Study 2018, ' Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci ', Nature Genetics, vol. 50, no. 7, 8, pp. 928-936 . https://doi.org/10.1038/s41588-018-0142-8
Nature Genetics, 50(7), 928-+. Nature Publishing Group
the Profile Study 2018, ' Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci ', Nature Genetics, vol. 50, no. 7, 8, pp. 928-936 . https://doi.org/10.1038/s41588-018-0142-8
Nature Genetics, 50(7), 928-+. Nature Publishing Group
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom high-density array of 46,939 PrCa cases and 27,910 controls
Autor:
Benjamin F. Voight, Stefania Bandinelli, Pascal Bovet, Latonya F. Been, Ci Song, Luigi Ferrucci, Johannes Kettunen, Andrew D. Morris, Mary Susan Burnett, Ronald M. Krauss, Igor Rudan, Heleen M. den Hertog, Stavroula Kanoni, G. Kees Hovingh, Elina Hyppönen, Kauko Heikkilä, Richard S. Cooper, Daniel I. Chasman, Bruna Gigante, Stefan Gustafsson, Jian'an Luan, Sarah H. Wild, Patricia B. Munroe, Göran Hallmans, Jeffrey R. O'Connell, Danish Saleheen, Aarno Palotie, Leena Moilanen, Jerome I. Rotter, Caroline Hayward, Jennifer L. Bragg-Gresham, Nicholas G. Martin, Claudia Langenberg, George Dedoussis, Carlo Sidore, Ulf Gyllensten, Marika Kaakinen, Jing Hua Zhao, Aimo Ruokonen, Diana Kuh, Maria Dimitriou, Shih-Yi Lin, Gina M. Peloso, Marcus E. Kleber, Christopher J. Groves, Alena Stančáková, Michel Burnier, Patrik K. E. Magnusson, John C. Chambers, Giancarlo Cesana, Francis S. Collins, Gabrielle Müller, Angela Döring, Colin A. McKenzie, Paul Elliott, Lars Lind, Vilmundur Gudnason, Dharambir K. Sanghera, Jean Ferrières, Toshiko Tanaka, Stefan R. Bornstein, Gershim Asiki, Jacques S. Beckmann, Anneli Pouta, Timo A. Lakka, Daniel J. Rader, Elizabeth H. Young, Kelly A. Volcik, Dena G. Hernandez, Ann-Kristin Petersen, Kristian Hveem, Amy J. Swift, Murielle Bochud, Pierre Meneton, Paul M. Ridker, Kathleen Stirrups, Stephen S. Rich, Isleifur Olafsson, Ruth J. F. Loos, Serena Sanna, Markus Perola, Meena Kumari, Cameron D. Palmer, Carlos Iribarren, Nancy L. Pedersen, Mark O. Goodarzi, Panos Deloukas, Norman Klopp, Cristina Pomilla, Stephen E. Epstein, Antti Jula, Themistocles L. Assimes, Martina Müller-Nurasyid, Marjo-Riitta Järvelin, Chao A. Hsiung, Sonia Shah, Christian Gieger, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Nicholas J. Wareham, Krista Fischer, Wendy L. McArdle, Linda S. Adair, Kay-Tee Khaw, Bruce M. Psaty, André G. Uitterlinden, Aaron Isaacs, Tõnu Esko, Jennifer L. Bolton, Rebecca N. Nsubuga, Eric Boerwinkle, L. Joost van Pelt, Jouko Saramies, François Mach, Pierre Fontanillas, Teresa Ferreira, Lars Wallentin, Michael Boehnke, Christa Meisinger, Wayne Huey-Herng Sheu, Gonçalo R. Abecasis, Inês Barroso, Franklyn I. Bennett, Dmitry Shungin, Jaakko Kaprio, Kirsten Ohm Kyvik, Deepti Gurdasani, Anne U. Jackson, Paolo Brambilla, Georg Ehret, Cecilia M. Lindgren, Fernando Rivadeneira, Theodore Papamarkou, Jaakko Tuomilehto, Cristen J. Willer, Martin L. Buchkovich, Antero Kesäniemi, Hubert Scharnagl, Xiaohui Li, Elena Tremoli, Nelson B. Freimer, Mika Kähönen, Ron Do, Karen L. Mohlke, Thomas Illig, Gudmar Thorleifsson, Peter J. Koudstaal, Andres Metspalu, Ulf de Faire, Dominique Arveiler, Harald Grallert, Jaana Lindström, Laurence Tiret, Jaspal S. Kooner, Braxton D. Mitchell, Sebanti Sengupta, Gonneke Willemsen, Anna-Liisa Hartikainen, Terho Lehtimäki, Steve E. Humphries, Peter Schwarz, Dorret I. Boomsma, Harry Campbell, Ellen M. Schmidt, Tom Wilsgaard, Janet Seeley, Alex S. F. Doney, Alan R. Shuldiner, John Whitfield, Markku Laakso, Peter Vollenweider, Gudmundur I. Eyjolfsson, Winfried März, Mika Kivimäki, Ying Wu, Johanna Kuusisto, Andrew A. Hicks, Bruce H. R. Wolffenbuttel, May E. Montasser, Bamidele O. Tayo, Unnur Thorsteinsdottir, Muredach P. Reilly, Leo-Pekka Lyytikäinen, Eric Kim, John Danesh, Ida Surakka, Åsa Johansson, Anders Hamsten, Thomas Quertermous, Hsing-Yi Chang, Jin Chen, Agneta Siegbahn, Narisu Narisu, Samia Mora, Erik Ingelsson, Colin N. A. Palmer, Sekar Kathiresan, Manjinder S. Sandhu, Leif Groop, Jose M. Ordovas, Alan B. Feranil, Evelin Mihailov, Hilma Holm, Pontiano Kaleebu, Lindsay L. Waite, Ramaiah Nagaraja, Andrew Wong, Rona J. Strawbridge, David P. Strachan, Yii-Der Ida Chen, Tamara B. Harris, Jackie F. Price, Aravinda Chakravarti, Veikko Salomaa, Sailaja Vedantam, Albert Hofman, Devin Absher, Ross M. Fraser, Kaisa Silander, Pirjo Komulainen, Yi Jen Hung, Peter P. Pramstaller, Kari Stefansson, Aroon D. Hingorani, Tanya M. Teslovich, Matti Uusitupa, L. Adrienne Cupples, Cisca Wijmenga, Lori L. Bonnycastle, Ilja M. Nolte, Andrea Ganna, Ken K. Ong, Inger Njølstad, Bernhard O. Boehm, Nicholas W.J. Wainwright, Richa Saxena, Rainer Rauramaa, Louise A. Donnelly, James F. Wilson, Matthew Jones, Ingrid B. Borecki, Steven C. Hunt, Weihua Zhang, Massimo Mangino, John J.P. Kastelein, Martha L. Gravito, Mark I. McCarthy, Evita G. Van Den Herik, Joel N. Hirschhorn, Nilesh J. Samani, Daniel F. Freitag, Ayse Demirkan, Mary F. Feitosa, Tuomo Nieminen, Tim D. Spector, Paul W. Franks, Chris Power
Publikováno v:
Nature Genetics; Vol 45
Nature Genetics, 45(11), 1274-1283. Nature Publishing Group
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H-Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L-P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Bolton, J L, Hayward, C, Rudan, I, Wild, S H, Wilson, J F, Campbell, H & Morris, A & Price, J F 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-83 . https://doi.org/10.1038/ng.2797
Nature genetics
Nature genetics, 45(11), 1274-1283. Nature Publishing Group
Nature Genetics, Vol. 45, No 11 (2013) pp. 1274-83
Nature Genetics, 45(11), 1274-+. Nature Publishing Group
NATURE GENETICS
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L P, Magnusson, P K, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifson, G, van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S Y, Lindström, J, Loos, R J, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N J, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N W, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A D, Hirschhorn, J N, Hofman, A, Hovingh, K G, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E, Sheu, W H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H, Ordovas, J, Boerwinkle, E, Palmer, C N, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E & Abecasis, G R 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkila, K, Hypponen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X H, Luan, J A, Lyytikainen, L P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Muller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W H, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Doring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimaki, T, Lin, S Y, Lindstrom, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Muller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrieres, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Jarvelin, M R, Jula, A, Kahonen, M, Kaprio, J, Kesaniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, Marz, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E, Abecasis, G R & Global Lipids Genetics, C 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Nature Genetics
Nature Genetics, vol. 45, no. 11, pp. 1274-1283
Nature Genetics, 45(11), 1274-1283. Nature Publishing Group
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H-Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L-P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Bolton, J L, Hayward, C, Rudan, I, Wild, S H, Wilson, J F, Campbell, H & Morris, A & Price, J F 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-83 . https://doi.org/10.1038/ng.2797
Nature genetics
Nature genetics, 45(11), 1274-1283. Nature Publishing Group
Nature Genetics, Vol. 45, No 11 (2013) pp. 1274-83
Nature Genetics, 45(11), 1274-+. Nature Publishing Group
NATURE GENETICS
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L P, Magnusson, P K, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifson, G, van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S Y, Lindström, J, Loos, R J, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N J, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N W, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A D, Hirschhorn, J N, Hofman, A, Hovingh, K G, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E, Sheu, W H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H, Ordovas, J, Boerwinkle, E, Palmer, C N, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E & Abecasis, G R 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, no. 11, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Willer, C J, Schmidt, E M, Sengupta, S, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, Den Hertog, H M, Do, R, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkila, K, Hypponen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X H, Luan, J A, Lyytikainen, L P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Muller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W H, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Doring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimaki, T, Lin, S Y, Lindstrom, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Muller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrieres, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Jarvelin, M R, Jula, A, Kahonen, M, Kaprio, J, Kesaniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, Marz, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Kathiresan, S, Mohlke, K L, Ingelsson, E, Abecasis, G R & Global Lipids Genetics, C 2013, ' Discovery and refinement of loci associated with lipid levels ', Nature Genetics, vol. 45, pp. 1274-1283 . https://doi.org/10.1038/ng.2797
Nature Genetics
Nature Genetics, vol. 45, no. 11, pp. 1274-1283
Levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides and total cholesterol are heritable, modifiable risk factors for coronary artery disease. To identify new loci and refine known loci influe
Autor:
Norman Klopp, Chih-Mei Chen, Erik Melén, Dirkje S. Postma, Klaus Bønnelykke, Gerard H. Koppelman, Ivan Curjuric, Massimo Mangino, Nicholas J. Timpson, Alexandra I. F. Blakemore, Stephen B. Montgomery, Marjo-Riitta Järvelin, Anneli Pouta, Dorret I. Boomsma, Melanie C. Matheson, Albert Hofman, Matthias Wjst, Hans Bisgaard, Natalija Novak, Deborah Jarvis, Grant W. Montgomery, Frank Geller, Beate St Pourcain, Craig E. Pennell, Manuel A. R. Ferreira, Andre Franke, Alexessander Couto Alves, Frank D. Mentch, Vincent W. V. Jaddoe, Marie Standl, Nicole M. Warrington, Jouke-Jan Hottenga, Jessica L. Buxton, Peter N. Le Souëf, Bjarke Feenstra, Peter D. Sly, Bo L. Chawes, Martina Mueller-Nurasyid, Angela Simpson, Philip J. Thompson, Jacob P. Thyssen, Patrick G. Holt, Eskil Kreiner-Møller, David L. Duffy, Thomas Illig, Johan C. de Jongste, Bo Jacobsson, Joachim Heinrich, Mads Melbye, Wenche Nystad, H-Erich Wichmann, Medea Imboden, Wendy L. McArdle, Carla M. T. Tiesler, Susan M. Ring, Jeff Murray, Lavinia Paternoster, Torkil Menné, Marjan Kerkhof, John Henderson, Ronny Myhre, Lyle J. Palmer, George Davey Smith, Eva Albrecht, Pamela A. F. Madden, Marika Kaakinen, Hansjoerg Baurecht, Nicole Probst-Hensch, Cecilia Kim, Cornelia M. van Duijin, Panos Deloukas, Patrick M. A. Sleiman, Christian Gieger, John A. Curtin, Adnan Custovic, Daniel Glass, Cilla Söderhäll, Annika Sääf, Elke Rodriguez, Nicholas G. Martin, Stephan Weidinger, Tim D. Spector, Adaikalavan Ramasamy, John P. Kemp, Heather A. Boyd, Elisabeth Thiering, David P. Strachan, Anna-Liisa Hartikainen, Hakon Hakonarson, Allan Linneberg, Ralf J. P. van der Valk, Pirro G. Hysi, David M. Evans, Rain Jögi, Ellen A. Nohr, Liesbeth Duijts, Katharina Heim, Veronique Bataille, Fernando Rivadeneira, Maria M. Groen-Blokhuis, Andrew C. Heath, David Ellinghaus, Michael E. March, Holger Prokisch, Regina Foelster-Holst, André G. Uitterlinden, Emmanouil T. Dermitzakis, Juha Pekkanen, Henriette A. Smit
Publikováno v:
Paternoster, L, Standl, M, Chen, C-M, Ramasamy, A, Bønnelykke, K, Duijts, L, Ferreira, M A, Alves, A C, Thyssen, J P, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, P M A, Hysi, P, Warrington, N M, Curjuric, I, Myhre, R, Curtin, J A, Groen-Blokhuis, M M, Kerkhof, M, Sääf, A, Franke, A, Ellinghaus, D, Fölster-Holst, R, Dermitzakis, E, Montgomery, S B, Prokisch, H, Heim, K, Hartikainen, A-L, Pouta, A, Pekkanen, J, Blakemore, A I F, Buxton, J L, Kaakinen, M, Duffy, D L, Madden, P A, Heath, A C, Montgomery, G W, Thompson, P J, Matheson, M C, Le Souëf, P, Pourcain, B S, Smith, G D, Henderson, J, Kemp, J P, Timpson, N J, Deloukas, P, Ring, S M, Wichmann, H-E, Nøhr, E A & Australian Asthma Genetics Consortium (AAGC) 2011, ' Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis ', Nature Genetics, vol. 44, no. 2, pp. 187-192 . https://doi.org/10.1038/ng.1017
Nature Genetics
Nature Genetics; Vol 44
Paternoster, L, Standl, M, Chen, C-M, Ramasamy, A, Bønnelykke, K, Duijts, L, Ferreira, M A, Alves, A C, Thyssen, J P, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, P M A, Hysi, P, Warrington, N M, Curjuric, I, Myhre, R, Curtin, J A, Groen-Blokhuis, M M, Kerkhof, M, Sääf, A, Franke, A, Ellinghaus, D, Fölster-Holst, R, Dermitzakis, E, Montgomery, S B, Prokisch, H, Heim, K, Hartikainen, A-L, Pouta, A, Pekkanen, J, Blakemore, A I F, Buxton, J L, Kaakinen, M, Duffy, D L, Madden, P A, Heath, A C, Montgomery, G W, Thompson, P J, Matheson, M C, Le Souëf, P, Pourcain, B S, Smith, G D, Henderson, J, Kemp, J P, Timpson, N J, Deloukas, P, Ring, S M, Nøhr, E A, Jacobsson, B & Australian Asthma Genetics Consortium (AAGC) 2011, ' Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis ', Nature Genetics, vol. 44, no. 2, pp. 187-192 . https://doi.org/10.1038/ng.1017
Nature Genetics, Vol. 44, No 2 (2012) pp. 187-92
Nature genetics
Nature Genetics, 44(2), 187-192. Nature Publishing Group
Paternoster, L, Standl, M, Chen, C-M, Ramasamy, A, Bonnelykke, K, Duijts, L, Ferreira, M A, Alves, A C, Thyssen, J P, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, P M A, Hysi, P, Warrington, N M, Curjuric, I, Myhre, R, Curtin, J A, Groen-Blokhuis, M M, Kerkhof, M, Saaf, A, Franke, A, Ellinghaus, D, Foelster-Holst, R, Dermitzakis, E, Montgomery, S B, Prokisch, H, Heim, K, Hartikainen, A-L, Pouta, A, Pekkanen, J, Blakemore, A I F, Buxton, J L, Kaakinen, M, Duffy, D L, Madden, P A, Heath, A C, Montgomery, G W, Thompson, P J, Matheson, M C, Le Souef, P, St Pourcain, B, Smith, G D, Henderson, J, Kemp, J P, Timpson, N J, Deloukas, P, Ring, S M, Wichmann, H-E, Mueller-Nurasyid, M, Novak, N, Klopp, N, Rodriguez, E, McArdle, W, Linneberg, A, Menne, T, Nohr, E A, Hofman, A, Uitterlinden, A G, van Duijin, C M, Rivadeneira, F, de Jongste, J C, van der Valk, R J P, Wjst, M, Jogi, R, Geller, F, Boyd, H A, Murray, J C, Kim, C, Mentch, F, March, M, Mangino, M, Spector, T D, Bataille, V, Pennell, C E, Holt, P G, Sly, P, Tiesler, C M T, Thiering, E, Illig, T, Imboden, M, Nystad, W, Simpson, A, Hottenga, J-J, Postma, D, Koppelman, G H, Smit, H A, Soderhall, C, Chawes, B, Kreiner-Moller, E, Bisgaard, H, Melen, E, Boomsma, D I, Custovic, A, Jacobsson, B, Probst-Hensch, N M, Palmer, L J, Glass, D, Hakonarson, H, Melbye, M, Jarvis, D L, Jaddoe, V W V, Gieger, C, Strachan, D P, Martin, N G, Jarvelin, M-R, Heinrich, J, Evans, D M & Weidinger, S 2012, ' Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis ', Nature Genetics, vol. 44, no. 2, pp. 187-192 . https://doi.org/10.1038/ng.1017
Paternoster, L, Standl, M, Chen, C M, Ramasamy, A, Bønnelykke, K, Duijts, L, Ferreira, M A, Couto Alves, A, Thyssen, J P, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, P M A, Hysi, P, Warrington, N M, Curjuric, I, Myhre, R, Curtin, J A, Groen-Blokhuis, M M, Kerkhof, M, Sääf, A, Franke, A, Ellinghaus, D, Fölster-Holst, R, Dermitzakis, E, Montgomery, S B, Prokisch, H, Heim, K, Hartikainen, A-L, Pouta, A, Pekkanen, J, Blakemore, A I F, Buxton, J L, Kaakinen, M, Duffy, DL, Madden, P A F, Heath, A C, Montgomery, G W, Thompson, P J, Matheson, M C, Le Souëf, P, St Pourcain, B, Davey Smith, G, Henderson, J, Kemp, J P, Timpson, N J, Deloukas, P, Ring, S M, Wichmann, H-E, Müller-Nurasyid, M, Novak, N, Klopp, N, Rodríguez, E, McArdle, W, Linneberg, A, Menné, T, Nohr, E A, Hofman, A, Uitterlinden, A G, van Duijn, C M, Rivadeneira, F, de Jongste, J C, van der Valk, R J P, Wjst, M, Jogi, R, Geller, F, Boyd, H A, Murray, J C, Kim, C, Mentch, F, March, M, Mangino, M, Spector, T D, Bataille, V, Pennell, C E, Holt, P G, Sly, P, Tiesler, C M T, Hottenga, J J, Boomsma, D I, Hakonarson, H, Melbye, M, Ljarvis, D, Jaddoe, V W V, Gieger, C, Strachan, D P, Martin, N G, Jarvelin, M-R, Heinrich, J, Evans, D M & Weidinger, S 2012, ' Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis ', Nature Genetics, vol. 44, no. 2, pp. 187-192 . https://doi.org/10.1038/ng.1017
Nature Genetics
Nature Genetics; Vol 44
Paternoster, L, Standl, M, Chen, C-M, Ramasamy, A, Bønnelykke, K, Duijts, L, Ferreira, M A, Alves, A C, Thyssen, J P, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, P M A, Hysi, P, Warrington, N M, Curjuric, I, Myhre, R, Curtin, J A, Groen-Blokhuis, M M, Kerkhof, M, Sääf, A, Franke, A, Ellinghaus, D, Fölster-Holst, R, Dermitzakis, E, Montgomery, S B, Prokisch, H, Heim, K, Hartikainen, A-L, Pouta, A, Pekkanen, J, Blakemore, A I F, Buxton, J L, Kaakinen, M, Duffy, D L, Madden, P A, Heath, A C, Montgomery, G W, Thompson, P J, Matheson, M C, Le Souëf, P, Pourcain, B S, Smith, G D, Henderson, J, Kemp, J P, Timpson, N J, Deloukas, P, Ring, S M, Nøhr, E A, Jacobsson, B & Australian Asthma Genetics Consortium (AAGC) 2011, ' Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis ', Nature Genetics, vol. 44, no. 2, pp. 187-192 . https://doi.org/10.1038/ng.1017
Nature Genetics, Vol. 44, No 2 (2012) pp. 187-92
Nature genetics
Nature Genetics, 44(2), 187-192. Nature Publishing Group
Paternoster, L, Standl, M, Chen, C-M, Ramasamy, A, Bonnelykke, K, Duijts, L, Ferreira, M A, Alves, A C, Thyssen, J P, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, P M A, Hysi, P, Warrington, N M, Curjuric, I, Myhre, R, Curtin, J A, Groen-Blokhuis, M M, Kerkhof, M, Saaf, A, Franke, A, Ellinghaus, D, Foelster-Holst, R, Dermitzakis, E, Montgomery, S B, Prokisch, H, Heim, K, Hartikainen, A-L, Pouta, A, Pekkanen, J, Blakemore, A I F, Buxton, J L, Kaakinen, M, Duffy, D L, Madden, P A, Heath, A C, Montgomery, G W, Thompson, P J, Matheson, M C, Le Souef, P, St Pourcain, B, Smith, G D, Henderson, J, Kemp, J P, Timpson, N J, Deloukas, P, Ring, S M, Wichmann, H-E, Mueller-Nurasyid, M, Novak, N, Klopp, N, Rodriguez, E, McArdle, W, Linneberg, A, Menne, T, Nohr, E A, Hofman, A, Uitterlinden, A G, van Duijin, C M, Rivadeneira, F, de Jongste, J C, van der Valk, R J P, Wjst, M, Jogi, R, Geller, F, Boyd, H A, Murray, J C, Kim, C, Mentch, F, March, M, Mangino, M, Spector, T D, Bataille, V, Pennell, C E, Holt, P G, Sly, P, Tiesler, C M T, Thiering, E, Illig, T, Imboden, M, Nystad, W, Simpson, A, Hottenga, J-J, Postma, D, Koppelman, G H, Smit, H A, Soderhall, C, Chawes, B, Kreiner-Moller, E, Bisgaard, H, Melen, E, Boomsma, D I, Custovic, A, Jacobsson, B, Probst-Hensch, N M, Palmer, L J, Glass, D, Hakonarson, H, Melbye, M, Jarvis, D L, Jaddoe, V W V, Gieger, C, Strachan, D P, Martin, N G, Jarvelin, M-R, Heinrich, J, Evans, D M & Weidinger, S 2012, ' Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis ', Nature Genetics, vol. 44, no. 2, pp. 187-192 . https://doi.org/10.1038/ng.1017
Paternoster, L, Standl, M, Chen, C M, Ramasamy, A, Bønnelykke, K, Duijts, L, Ferreira, M A, Couto Alves, A, Thyssen, J P, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, P M A, Hysi, P, Warrington, N M, Curjuric, I, Myhre, R, Curtin, J A, Groen-Blokhuis, M M, Kerkhof, M, Sääf, A, Franke, A, Ellinghaus, D, Fölster-Holst, R, Dermitzakis, E, Montgomery, S B, Prokisch, H, Heim, K, Hartikainen, A-L, Pouta, A, Pekkanen, J, Blakemore, A I F, Buxton, J L, Kaakinen, M, Duffy, DL, Madden, P A F, Heath, A C, Montgomery, G W, Thompson, P J, Matheson, M C, Le Souëf, P, St Pourcain, B, Davey Smith, G, Henderson, J, Kemp, J P, Timpson, N J, Deloukas, P, Ring, S M, Wichmann, H-E, Müller-Nurasyid, M, Novak, N, Klopp, N, Rodríguez, E, McArdle, W, Linneberg, A, Menné, T, Nohr, E A, Hofman, A, Uitterlinden, A G, van Duijn, C M, Rivadeneira, F, de Jongste, J C, van der Valk, R J P, Wjst, M, Jogi, R, Geller, F, Boyd, H A, Murray, J C, Kim, C, Mentch, F, March, M, Mangino, M, Spector, T D, Bataille, V, Pennell, C E, Holt, P G, Sly, P, Tiesler, C M T, Hottenga, J J, Boomsma, D I, Hakonarson, H, Melbye, M, Ljarvis, D, Jaddoe, V W V, Gieger, C, Strachan, D P, Martin, N G, Jarvelin, M-R, Heinrich, J, Evans, D M & Weidinger, S 2012, ' Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis ', Nature Genetics, vol. 44, no. 2, pp. 187-192 . https://doi.org/10.1038/ng.1017
Atopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability. Apart from filaggrin (FLG), the genes influencing atopic dermatitis are largely unknown. We conducted a genome-wide association meta-analysis of 5,606 affecte