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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Genetic polymorphisms of NEIL1 and NEIL2 maybe change protein function, and increased carcinogenesis. In this study, seven NEIL1 SNPs and three NEIL2 SNPs were selected. 400 CSCCs, 400 CIN III, and 1200 normal healthy controls were genotyped by misma
Autor:
Yanhui Gao, Li Liu, Ziqiang Lin, Zhifeng Lin, Lucheng Pi, Nana Tian, Sidong Chen, Xinqi Lin, Junguo Zhang, Xiaohui Ji, Xinfa Yu
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports
As a long non-coding RNA (lncRNA) and a transcriptional regulator, Metastasis associated lung adenocarcioma transcript-1 (MALAT-1) has been reported to be associated with proliferation and metastasis of hepatocellular carcinoma (HCC). However, the ef
Autor:
Francisco J. López-Hernández, Luis García-Ortiz, Manuel A. Gómez-Marcos, Nuria Perretta-Tejedor, Mercedes Garzon-Martinez, Rogelio González-Sarmiento, Carlos Martínez-Salgado
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
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Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
© The Author(s) 2020.
Cardiovascular diseases are associated to risk factors as obesity, hypertension and diabetes. The transforming growth factor-β1 receptors ALK1 and endoglin regulate blood pressure and vascular homeostasis. However, no stu
Cardiovascular diseases are associated to risk factors as obesity, hypertension and diabetes. The transforming growth factor-β1 receptors ALK1 and endoglin regulate blood pressure and vascular homeostasis. However, no stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afd1b85cc9921541dc655109dc798d7
http://hdl.handle.net/10261/226460
http://hdl.handle.net/10261/226460
Autor:
Tien Yin Wong, Jiemin Liao, Carol Y. Cheung, Tai E. Shyong, M. Kamran Ikram, Ching-Yu Cheng, Ling-Jun Li
Publikováno v:
Scientific Reports
We aimed to determine the association between blood pressure (BP) and retinal vascular caliber changes that were free from confounders and reverse causation by using Mendelian randomisation. A total of 6528 participants from a multi-ethnic cohort (Ch
Autor:
Dipika Desai, David Meyre, Salim Yusuf, James C. Engert, Jackie Bosch, Viswanathan Mohan, Rafael Diaz, Hudson Reddon, Swneke D. Bailey, Hertzel C. Gerstein, Sonia S. Anand
Publikováno v:
Scientific Reports
Physical activity (PA) has been shown to reduce the impact of FTO variation and obesity genetic risk scores (GRS) on BMI. We examined this interaction using a quantitative measure of PA and two adiposity indexes in a longitudinal multi-ethnic study.
Autor:
Cheng Wang, Wei Shen, Guangfu Jin, Hongxia Ma, Jia Liu, Hongbing Shen, Zhibin Hu, Juncheng Dai, Meng Zhu, Liguo Geng, Yang Cheng, Yuzhuo Wang
Publikováno v:
Scientific Reports
APOBEC (Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) enzymes may involve in mutagenic processes in multiple cancer types, including lung cancer. APOBEC family of cytidine deaminases induces base substitutions with a stringent TCW
Autor:
Jinhong Zhu, Meiling Zhu, Qingyi Wei, Jiucun Wang, Jin He, Li Jin, Xiaofeng Wang, Jia Qing Xiang, Mengyun Wang
Publikováno v:
Scientific Reports
Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1 and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) patients and 1117 cancer
Autor:
Manon van Engeland, Piet A. van den Brandt, Matty P. Weijenberg, Roger W. L. Godschalk, Colinda C. J. M. Simons, Leo J. Schouten, Frederik J. van Schooten
Publikováno v:
Scientific Reports
Scientific Reports, 5:14126. Nature Publishing Group
Scientific Reports, 5:14126. Nature Publishing Group
Interrelationships between insulin-like growth factors (IGFs), hyperinsulinaemia, diabetes and colorectal cancer (CRC) indicate involvement of IGFs in colorectal tumorigenesis. We investigated the CRC risk associated with 24 single nucleotide polymor
Autor:
Lei Sun, Clement C. Zai, Andriy Derkach, James L. Kennedy, Arun K. Tiwari, Jeffrey A. Lieberman, Daniel J. Müller, Vanessa F. Gonçalves, Eva J. Brandl, Herbert Y. Meltzer
Mitochondria are the main source of energy for neurons and have a role in many vital neuronal functions. Mitochondrial dysfunction has been described in schizophrenia, and antipsychotics such as clozapine and olanzapine have been associated with diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4027ed9bb13fcfad0b9b2882b470ac33
https://europepmc.org/articles/PMC3988538/
https://europepmc.org/articles/PMC3988538/