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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Acute cerebral ischaemia may lead to serious consequences, including brain injury caused by uncontrolled reperfusion, which occurs when circulation is re-established. The long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) pla
Autor:
Patrick M Noone, Masayuki Yamamoto, Haranatha R. Potteti, Thomas W. Kensler, Narsa M. Reddy, Chandra Mohan Tamatam, Aparna Ankireddy, Sekhar P. Reddy
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Bronchopulmonary dysplasia (BPD) is a chronic disease of preterm babies with poor clinical outcomes. Nrf2 transcription factor is crucial for cytoprotective response, whereas Keap1—an endogenous inhibitor of Nrf2 signaling—dampens these protectiv
Autor:
Franck Zal, Nadia Benkirane-Jessel, Elisabeth Leize-Zal, Céline Stutz, Eric Delpy, Catherine Petit, Olivier Huck, Fareeha Batool
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The control of inflammation and infection is crucial for periodontal wound healing and regeneration. M101, an oxygen carrier derived from Arenicola marina, was tested for its anti-inflammatory and anti-infectious potential based on its anti-oxidative
Autor:
Francis Migneault, Alexandre Brodeur, Nicolas Thibodeau, Mélanie Dieudé, Marie-Pierre Hardy, Deborah Beillevaire, Claude Perreault, Julie Turgeon, Marie-Josée Hébert
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Persistent endothelial injury promotes maladaptive responses by favoring the release of factors leading to perturbation in vascular homeostasis and tissue architecture. Caspase-3 dependent death of microvascular endothelial cells leads to the release
Autor:
Guozhang He, Wei Shu, Hua Yang, Yanling Yao, Ming Chen, Zuping Zhou, Taj-Malook Khan, Yaping Li, Shiming Pu, Guangying Qi, Baohua Huang, Xin Liu, Shuang Kan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The function of Latexin (LXN) in inflammation has attracted attention. However, no data are available regarding its role in colitis. We report that LXN is a suppressor of colitis. LXN deficiency leads to the severity of colitis in DSS-induced mice, a
Autor:
Ritsumi Saito, Teiji Tominaga, Masayuki Yamamoto, Daisuke Saigusa, Takahiro Yamazaki, Yoshihisa Tomioka, Akira Uruno, Yotaro Matsumoto, Sherif Rashad, Kuniyasu Niizuma
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Understanding the root causes of neuronal vulnerability to ischemia is paramount to the development of new therapies for stroke. Transient global cerebral ischemia (tGCI) leads to selective neuronal cell death in the CA1 sub-region of the hippocampus
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Two distinct p38 signaling pathways, classical and alternative, have been identified to regulate inflammatory responses in host defense and disease development. The role of alternative p38 activation in liver inflammation is elusive, while classical
Autor:
Isidro-Hernández, M., Mayado, A., Casado-García, A., Martínez-Cano, J., Palmi, C., Fazio, G., Orfao, A., Ribera Salas, Jordi, Ribera, Jose-Maria, Zamora, Lurdes, Raboso-Gallego, J., Blanco, O., Alonso-López, D., De Las Rivas, J., Jiménez, R., García Criado, F.J., García Cenador, M.B., Ramírez-Orellana, M., Cazzaniga, G., Cobaleda, C., Vicente-Dueñas, C., Sánchez-García, I., Universitat Autònoma de Barcelona
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
© The Author(s) 2020.
PAX5 is one of the most frequently mutated genes in B-cell acute lymphoblastic leukemia (B-ALL), and children with inherited preleukemic PAX5 mutations are at a higher risk of developing the disease. Abnormal profiles of i
PAX5 is one of the most frequently mutated genes in B-cell acute lymphoblastic leukemia (B-ALL), and children with inherited preleukemic PAX5 mutations are at a higher risk of developing the disease. Abnormal profiles of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c172ad82beb6a69df4e91659264ec57
http://hdl.handle.net/10261/226516
http://hdl.handle.net/10261/226516
Autor:
Jie Zhou, Charles N. Rotimi, Adebowale Adeyemo, Amadou Gaye, Gary H. Gibbons, Ayo P. Doumatey, Lin Lei, William J. He
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Obese individuals without expected metabolic co-morbidities are referred to as metabolically healthy obese (MHO). The molecular mechanisms underlying this phenotype remain elusive. MicroRNAs may be involved in the MHO phenotype. To test this hypothes