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Autor:
Jee Hye Choi, Sangmyung Rhee, Sung Haeng Lee, Simon Lovestone, Lee Sael, Ah Ra Do, Jungsoo Gim, Suparna Ghosh, Sanghun Lee, Kyu Yeong Choi, SangYun Kim, Seula Keum, Juhong Park, Lindsay A. Farrer, Jang Jae Lee, Andrew J. Saykin, Gyun Jee Song, Byeong C. Kim, Kwangsik Nho, Jun Young Park, Eunae Kim, Kun Ho Lee, Immanuel Dhanasingh, Seung Hwan Moon, Hoowon Kim, Kyungtaek Park, Donghe Li, Jinyeon Jo, Tamil Iniyan Gunasekaran, Dong Soo Lee, Sungho Won, Sarang Kang, Gyungah Jun
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Translational Psychiatry
Established genetic risk factors for Alzheimer’s disease (AD) account for only a portion of AD heritability. The aim of this study was to identify novel associations between genetic variants and AD-specific brain atrophy. We conducted genome-wide a
Autor:
Walter J.F.M. van der Velden, Anton F.J. de Haan, Nicole M. A. Blijlevens, Suzanne van Dorp, Jürgen Kuball, Moniek de Witte, Goda Choi, Arnold van der Meer, Gerwin Huls
Publikováno v:
Bone Marrow Transplantation, 56, 2651-2655
Bone Marrow Transplantation, 56, 11, pp. 2651-2655
Bone Marrow Transplantation
Bone marrow transplantation, 56(11), 2651-2655. Nature Publishing Group
Bone Marrow Transplantation, 56, 11, pp. 2651-2655
Bone Marrow Transplantation
Bone marrow transplantation, 56(11), 2651-2655. Nature Publishing Group
Contains fulltext : 241342.pdf (Publisher’s version ) (Closed access) Nonmyeloablative regimens are used for allogeneic hematopoietic cell transplantation (HCT) of older or medically unfit patients, but successful outcome is still hindered by graft
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Translational Psychiatry
Increasing evidences supported that subjective cognitive decline (SCD) might be a potential first symptomatic manifestation of Alzheimer’s disease (AD). The rapidly growing number of SCD individuals who seek medical help and advice also makes it ur
Autor:
Chen, Shi Dong, Lu, Jia Ying, Li, Hong Qi, Yang, Yu Xiang, Jiang, Jie Hui, Cui, Mei, Zuo, Chuan Tao, Tan, Lan, Dong, Qiang, Yu, Jin Tai, Weiner, Michael W., Aisen, Paul, Petersen, Ronald, Jack, Clifford R., Jagust, William, Trojanowki, John Q., Toga, Arthur W., Beckett, Laurel, Green, Robert C., Saykin, Andrew J., Morris, John C., Perrin, Richard J., Shaw, Leslie M., Carrillo, Maria, Potter, William, Barnes, Lisa, Bernard, Marie, González, Hector, Ho, Carole, Hsiao, John K., Jackson, Jonathan, Masliah, Eliezer
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Medical Biophysics Publications
Translational Psychiatry
Medical Biophysics Publications
A biological research framework to define Alzheimer’ disease with dichotomized biomarker measurement was proposed by National Institute on Aging–Alzheimer’s Association (NIA–AA). However, it cannot characterize the hierarchy spreading pattern
Autor:
Martin Gramatzki, Dietger Niederwieser, K. Boriskina, Arnon Nagler, Pavel Jindra, Justin Loke, Mohamad Mohty, Jan J. Cornelissen, Arnold Ganser, Charles Craddock, Bipin N. Savani, J Maertens, Didier Blaise, Myriam Labopin, B. Afansayev
Publikováno v:
Bone Marrow Transplantation, 56(3), 614-621. Nature Publishing Group
Patients with acute myeloid leukaemia (AML) who lack a matched sibling or unrelated donor commonly undergo transplantation from a donor matched at 9/10 HLA-A, -B, -C, -DRB1, -DQB1 alleles, and it is unclear if a specific locus mismatch is preferable
Autor:
Jordan F. Karp, James L. Kennedy, Sidney H. Kennedy, Roumen Milev, Eric J. Lenze, Daniel M. Blumberger, Farhana Islam, Daniel J. Müller, Gustavo Turecki, Benoit H. Mulsant, Etienne Sibille, Charles F. Reynolds, Victoria S. Marshe, Arun K. Tiwari, Raymond W. Lam, Malgorzata Maciukiewicz, Li Qin, Susan Rotzinger, Anne-Christin Hauschild, Benicio N. Frey, Alastair J. Flint, Jane A. Foster
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Translational Psychiatry
Antidepressant outcomes in older adults with depression is poor, possibly because of comorbidities such as cerebrovascular disease. Therefore, we leveraged multiple genome-wide approaches to understand the genetic architecture of antidepressant respo
Autor:
Ding-Yuan Tian, Xian-Le Bu, Pu-Yang Sun, Zhi-Qiang Xu, Yang Chen, Chen-Yang He, Yan-Jiang Wang, Hao-Lun Sun, Dong-Yu Fan, Ying-Ying Shen, Si-Han Chen, Fan Zeng, Juan Liu, Yuan Cheng, Juan Deng
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Translational Psychiatry
Translational Psychiatry
Deficits in the clearance of amyloid β-protein (Aβ) play a pivotal role in the pathogenesis of sporadic Alzheimer’s disease (AD). The roles of blood monocytes in the development of AD remain unclear. In this study, we sought to investigate the al
Autor:
Jun-Hyeok Kang, Wen-Fang Cheng, Yoo-Young Lee, Yen-Ling Lai, Hyun Soo Kim, Kuan-Ting Kuo, Yu-Li Chen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Low-grade ovarian serous carcinoma (LGSOC) has clinical features different from high-grade serous ovarian carcinoma (HGSOC) accounting for the majority of epithelial ovarian cancer. Because of its rarity, previous studies have only focused on the hig
Autor:
Xue-Yi Luo, Xiao-Hui Zhang, Feng-Rong Wang, Huan Chen, Wei Han, Chen-Hua Yan, Sining Liu, Yu Wang, Xiao-Jun Huang, Kai-Yan Liu, Lan-Ping Xu, Yu-Hong Chen, Jing-Zhi Wang, Xiao-Dong Mo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Relapse was the major cause of treatment failure in patients with acute lymphoblastic leukemia (ALL) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). We aimed to identify the efficacy and safety of preemptive interferon-α (IFN-
Autor:
Kuai Yu, Zhengming Chen, Canqing Yu, Wending Li, Yu Guo, Liming Li, Frank B. Hu, Tangchun Wu, Zheng Bian, Ling Yang, Yiping Chen, Jun Lv, Gaokun Qiu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Exhaled carbon monoxide (COex) level has been proposed as a noninvasive and easily-obtainable cardiovascular risk marker, however, with limited prospective evidence, and its association with stroke risk has been rarely explored. Measurements of COex