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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Omega-3 polyunsaturated fatty acids (PUFAs) have been known to have beneficial effects in the prevention of various diseases. Recently, it was identified that the bioactivities of omega-3 are related to lipid mediators, called pro-resolving lipid med
Autor:
José María Zapico, Gonzalo Herradón, Esther Gramage, M. Pilar Ramos-Alvarez, Marta Vicente-Rodríguez, Milagros Galán-Llario, María Uribarri, Rosalía Fernández-Calle, Marcel Ferrer-Alcón, Begoña Zapatería, Beatriz de Pascual-Teresa, Ana Ramos
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Pleiotrophin (PTN) is a cytokine that is upregulated in different neuroinflammatory disorders. Using mice with transgenic PTN overexpression in the brain (Ptn-Tg), we have found a positive correlation between iNos and Tnfα mRNA and Ptn mRNA levels i
Autor:
Tsung Wen Chong, June Jingyi Tai, Shazib Pervaiz, Siew Cheng Wong, Gregory Lucien Bellot, Binbin Wang, Herbert Schwarz, Kartini Iskandar, Fera Yiqian Goh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Sepsis is a potentially fatal condition triggered by systemic inflammatory response to infection. Due to the heightened immune reactivity and multi-organ pathology, treatment options are limited and several clinical trials have not produced the desir
Autor:
Massimo Pinzani, Alberto Quaglia, Stephen Davison, Jennifer Watkins, Emmanuel Tsochatzis, Andrew J. Hall, Sameh Abou-Beih, Tu Vinh Luong
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
The literature on the contribution of elastic fibre deposition to alcohol-related liver disease (ARLD) is limited. We studied: (1) 180 liver biopsies from ARLD patients; (2) 20 ARLD explant livers; (3) 213 liver biopsies with non-ARLD injury. Elastic
Autor:
Jaemyoung Sung, Takenori Inomata, Yuichi Okumura, Kenta Fujio, Jun Zhu, Akira Murakami, Naoko Negishi, Toshinari Funaki, Hurramhon Shokirova, Mikiko Okano, Maria Miura, Keiichi Fujimoto
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Corneal allograft survival is mediated by the variety of immunological reactions and wound healing process. Our aim was to explore the effects of topical administration of ripasudil, a selective Rho-associated coiled-coil protein kinase inhibitor, on
Autor:
Lígia Nunes de Morais Ribeiro, Gabriela Geronimo, Márcia Cristina Breitkreitz, Juan P. García-López, Eneida de Paula, Gustavo Henrique Rodrigues da Silva, Ludmilla David de Moura, Carmen G. Feijóo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Indexación Scopus Anesthetic failure is common in dental inflammation processes, even when modern agents, such as articaine, are used. Nanostructured lipid carriers (NLC) are systems with the potential to improve anesthetic efficacy, in which active
Autor:
Rowena Jenkins, Stephen J. Evans, A. John Simpson, Dietrich Mack, Thomas S. Wilkinson, Llinos G. Harris, Aled E. L. Roberts, Andrew Conway Morris
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of ventilator-associated pneumonia (VAP). Patients with VAP have poorly functioning neutrophils, related to increased levels of the complement fragment C5a. The antibiotic linez
Autor:
Amin Marghalani, Wael Yaghmoor, Isabel Carreras, Jae-Yong Ahn, Christina M. Tognoni, Danielle Stephens, Alpaslan Dedeoglu, Alpdogan Kantarci
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Periodontal disease (PD) has been suggested to be a risk factor for Alzheimer’s disease (AD). We tested the impact of ligature-induced PD on 5xFAD mice and WT littermates. At baseline, 5xFAD mice presented significant alveolar bone loss compared to
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
It has been demonstrated that Chikusetsusaponin IVa (CsIVa) possesses abundant biological activities. Herein, using LPS to establish acute inflammation model of mouse liver and cell line inflammation model, we investigated whether miR-155/GSK-3β reg
Autor:
Hanne Vanheel, Tim Vanuytsel, Silvia Cocca, Guy E. Boeckxstaens, Ricard Farré, Alison Accarie, Dorien Beeckmans, Gianluca Matteoli, Hans-Reimer Rodewald, María Vicario, Joran Toth, Jan Tack, Lucas Wauters, Gert De Hertogh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Duodenal hyperpermeability and low-grade inflammation in functional dyspepsia is potentially related to duodenal acid exposure. We aimed to evaluate in healthy volunteers the involvement of mast cell activation on the duodenogastric reflex and epithe