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Autor:
Xuxiu Tao, Jinwu Peng, San Xu, Lifang Yang, Dan Li, Xingzhi Peng, Zhuan Zhou, Liangfang Shen, Kun Zhang, Peijun Zhou
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Studies have indicated that dysfunction of autophagy is involved in the initiation and progression of multiple tumors and their chemoradiotherapy. Epstein–Barr virus (EBV) is a lymphotropic human gamma herpes virus that has been implicated in the p
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Osteosarcoma is the most common primary malignant tumor of bone derived from osteoblasts, which is a noteworthy threat to the health of children and adolescents. In this study, we found that MCM8 has significantly higher expression level in osteosarc
Autor:
Xianhui Ruan, Xiangqian Zheng, Dapeng Li, Ming Gao, Wei Zhang, Jingzhu Zhao, Xiukun Hou, Linfei Hu, Songfeng Wei, Xianle Shi, Jihong Yang, Xi Wei
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-18 (2021)
Cell Death & Disease
Cell Death & Disease
Papillary thyroid carcinoma (PTC) is one of the most common kinds of endocrine-related cancer and has a heterogeneous prognosis. Metabolic reprogramming is one of the hallmarks of cancers. Aberrant glucose metabolism is associated with malignant biol
Autor:
Shiting Li, Xuesheng Zheng, Xuan Zheng, Bowen Chang, Min Yang, Xueyi Wang, Lin Shen, Xiangyu Wei, Zheng Chen, Hanshuo Zhu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex, 4-like 2 (NDUFA4L2) is a subunit of Complex I of the mitochondrial respiratory chain, which is important in metabolic reprogramming and oxidative stress in multiple cancers. However, the biological
Autor:
Keisuke Tada, Hironari Nishizawa, Masafumi Onodera, Yusho Ishii, Mitsuyo Matsumoto, Akihiko Muto, Kozo Tanaka, Hiroki Kato, Guan Chen, Kazuhiko Igarashi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Ferroptosis is a regulated cell death due to the iron-dependent accumulation of lipid peroxide. Ferroptosis is known to constitute the pathology of ischemic diseases, neurodegenerative diseases, and steatohepatitis and also works as a suppressing mec
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-19 (2021)
Cell Death & Disease
Cell Death & Disease
Background: The long non-coding RNA (lncRNA),LINC00518, is highly expressed in many human cancers and is involved in cancer progression. However, the potential function and regulatory mechanism of LINC00518 in cutaneous malignant melanoma (CMM) remai
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
There is increasing evidence that the core clock gene Period 1 (PER1) plays important roles in the formation of various tumors. However, the biological functions and mechanism of PER1 in promoting tumor progression remain largely unknown. Here, we di
Autor:
Satoaki Matoba, Satoshi Gojo, Toshihiko Taya, Yosuke Suzuki, Daisuke Kami, Ryotaro Maeda, Akira Shikuma
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
The RNA decay pathway plays key regulatory roles in cell identities and differentiation processes. Although adipogenesis is transcriptionally and epigenetically regulated and has been thoroughly investigated, how RNA metabolism that contributes to th
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
PNO1 has been reported to be involved in tumorigenesis, however, its role in glioma remains unexplored. In the present study, PNO1 expression in glioma from on-line databases, cDNA, and tissue microarrays was upregulated and associated with poor prog
Autor:
Kyoung-Mi Lee, Jin Woo Lee, Dawoon Baek, Kwang Hwan Park, Sujin Jung, Jihyun Kim, Soyeong Joung
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
The ubiquitin protease pathway plays important role in human bone marrow-derived mesenchymal stem cell (hBMSC) differentiation, including osteogenesis. However, the function of deubiquitinating enzymes in osteogenic differentiation of hBMSCs remains