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Autor:
Wen-Jie Luo, Dingwei Ye, Yongqiang Huang, Yuan-Yuan Qu, Wenhao Xu, Mengfei Yao, Jun Wang, Chunguang Ma, Yiping Zhu, Hailiang Zhang, Fangning Wan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and development in bladder cancer. However, the underlying molecular mechanisms remain elusive. We previously identified a novel lncRNA signature related to immunity and prog
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
STEAP3 (Six-transmembrane epithelial antigen of the prostate 3, TSAP6, dudulin-2) has been reported to be involved in tumor progression in human malignancies. Nevertheless, how it participates in the progression of human cancers, especially HCC, is s
Autor:
Ruoyue Tan, Pan Huang, Yutao Wang, Yundong Zhang, Jianbing Hou, Yudong Liu, Hongjuan Cui, Dakun Pei
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
RAN binding protein 10 (RANBP10), a ubiquitously expressed and evolutionarily conserved protein, as a RAN-GTP exchange factor (GEF) to regulate several factors involved in cellular progression. Previous studies showed that RANBP10 was overexpressed i
Autor:
Zheng Li, Zhe Xuan, Jialun Lv, Guangli Sun, Hao Xu, Diancai Zhang, Hao Fan, Zekuan Xu, Jiacheng Cao, Linjun Wang, Yiwen Xia, Sen Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Gastric cancer (GC) ranks the third among global cancer-related mortality, especially in East Asia. Angiogenesis plays an important role in promoting tumor progression, and clinical trials have demonstrated that anti-angiogenesis therapy is effective
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Colorectal tumorigenesis is a heterogeneous disease driven by multiple genetic and epigenetic alterations. F-box and WD repeat domain containing 11 (FBXW11) is a member of the F-box protein family that regulates the ubiquitination of key factors asso
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Bladder cancer is one of the most lethal cancers in the world. Despite the continuous development of medical technologies and therapeutic strategies, the overall survival rate of bladder cancer has not changed significantly. Targeted therapy is a new
Autor:
Yu Ting Huang, Hui Chi Tang, Wei Yi Chen, Ping Hui Tseng, Guo Cheng Huang, Kou Juey Wu, Greg G. Wang, Ta Hsien Lin, An Chieh Cheng, Ling Cai
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
USP7, one of the most abundant ubiquitin-specific proteases (USP), plays multifaceted roles in many cellular events, including oncogenic pathways. Accumulated studies have suggested that USP7, through modulating the MDM2/MDMX-p53 pathway, is a promis
Autor:
Lu Liu, Kairong Han, Mingyue Tao, Zhengwei Zhang, Zhen Song, Tong Gu, Weiyong Yu, Xiaofei Chen, Xiaojuan Yu, Li Zhang, Xiujuan Huang, Chao Luo, Hao Gu, Jing Luo, Yali Jun, Qilong Wang, Su’an Sun
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)
Tumor cells require high levels of cholesterol for membrane biogenesis for rapid proliferation during development. Beyond the acquired cholesterol from low-density lipoprotein (LDL) taken up from circulation, tumor cells can also biosynthesize choles
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-9 (2021)
Cell Death & Disease
Cell Death & Disease
The lncRNA ZFAS1 plays a carcinogenic regulatory role in many human tumours, but it is rarely reported in pancreatic cancer. We identify the role and molecular mechanisms of ZFAS1 in pancreatic cancer. The expression of ZFAS1, miR-497-5p and HMGA2 in
Autor:
Congcong Zhang, Zhixian Wang, Xin Xu, Lifang Ma, Jiayi Wang, Yongjie Niu, Yongchun Yu, Yan Li
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Diabetes is an important risk factor for liver cancer, but its mechanism is unknown. Corosolic acid (CA) has been proven to have both hypoglycemic and antitumor effects, so revealing the function of CA can help us understand the relationship between