Zobrazeno 1 - 10
of 92
pro vyhledávání: ''
Autor:
Keisuke Tada, Hironari Nishizawa, Masafumi Onodera, Yusho Ishii, Mitsuyo Matsumoto, Akihiko Muto, Kozo Tanaka, Hiroki Kato, Guan Chen, Kazuhiko Igarashi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Ferroptosis is a regulated cell death due to the iron-dependent accumulation of lipid peroxide. Ferroptosis is known to constitute the pathology of ischemic diseases, neurodegenerative diseases, and steatohepatitis and also works as a suppressing mec
Autor:
Shuang Hui, Meng Ni, Yongxia Dang, Yating Yang, Menglan Niu, Zijie Zhang, Yuanyuan Wu, Yang Wang, Jiaxin Wang, Dengke Bao, Lixin Wan, Bo Wan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
TEFM (transcription elongation factor of mitochondria) has been identified as a novel nuclear-encoded transcription elongation factor in the transcription of mitochondrial genome. Our bioinformatics analysis of TCGA data revealed an aberrant over-exp
Autor:
Victor Peperzak, Monique C. Minnema, Anne Slomp, Eric Eldering, Marie José Kersten, Laura M Moesbergen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-11 (2021)
Cell Death & Disease
Cell death & disease, 12(3):229. Nature Publishing Group
Cell Death & Disease
Cell death & disease, 12(3):229. Nature Publishing Group
Multiple myeloma (MM), a treatable but incurable malignancy, is characterized by the growth of clonal plasma cells in protective niches in the bone marrow. MM cells depend on expression of BCL-2 family proteins, in particular MCL-1, for survival. The
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
There is increasing evidence that the core clock gene Period 1 (PER1) plays important roles in the formation of various tumors. However, the biological functions and mechanism of PER1 in promoting tumor progression remain largely unknown. Here, we di
Autor:
Jian Sun, Zhang-Fu Yang, Shuang-Jian Qiu, Yong Yi, Cheng Zhou, Ruo-Yu Guan, Gao Liu, Bao-Ye Sun, Pei-Yun Zhou, Jian Zhou, Jia Fan, Zhu-Tao Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-19 (2021)
Cell Death & Disease
Cell Death & Disease
Cancer-associated fibroblasts (CAFs) are commonly acquired activated extracellular matrix (ECM)-producing myofibroblasts, a phenotypes with multiple roles in hepatic fibrogenesis and carcinogenesis via crosstalk with cohabitating stromal/cancer cells
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
It is hypothesized that tumor-initiating cells (TICs) with stem cell-like properties constitute a sustaining force to drive tumor growth and renew fully established malignancy. However, the identification of such a population in non-small cell lung c
Autor:
Yuxin Tang, Kai Huang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
This study aimed to investigate the mechanism of SChLAP1 (second chromosome locus associated with prostate-1) on microRNA expression in prostate cancer. Differential expression of lncRNAs and microRNA prostate cancer cells were predicted by informati
Autor:
Wen-Hsuan Yang, Yitong Xu, Jen-Tsan Chi, Chao-Chieh Lin, Chien-Kuang Cornelia Ding, Po-Han Chen, Alexander A. Mestre, Jianli Wu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Ferroptosis is a newly described form of regulated cell death triggered by oxidative stresses and characterized by extensive lipid peroxidation and membrane damages. The name of ferroptosis indicates that the ferroptotic death process depends on iron
Autor:
Kaping Lee, Qian Long, Dongli Yue, Xiaohan Yao, Jieyao Li, Yixin Li, Liping Wang, Na Li, Shuangning Yang, Yanfen Liu, Zhuoyu Gu
Publikováno v:
Cell Death and Disease, Vol 11, Iss 10, Pp 1-16 (2020)
Cell Death & Disease
Cell Death & Disease
Currently, only a few available targeted drugs are considered to be effective in stomach adenocarcinoma (STAD) treatment. The PARP inhibitor olaparib is a molecularly targeted drug that continues to be investigated in BRCA-mutated tumors. However, in
Publikováno v:
Cell Death and Disease, Vol 11, Iss 10, Pp 1-10 (2020)
Cell Death & Disease
Cell Death & Disease
N6-methyladenosine (m6A) serves as the most common and conserved internal transcriptional modification. However, the roles of m6A on cervical cancer (CC) tumorigenesis are still unclear. Here, results indicated that METTL3 was significantly upregulat