Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Jiang A"'
Autor:
Yujin Shi, Wensheng Wei, Tao Jiao, Tian Zheng, Ruiyi Ma, Lili Ren, Qi Jiang, Zichun Xiang, Zhixun Dou, Jian Rao, Zhuo Zhou, Xinyi Zhang, Zhengfan Jiang, Jianwei Wang, Wenjing Wang, Xia Xiao, Tao Deng, Xiaojing Dong, Xiaobo Lei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
The global coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive-sense RNA virus. How the host immune system senses and responds to SARS-CoV-2 infection remain to be determi
Autor:
Jianwei Wang, Ronghua Hu, Min Xiao, Changcai Cao, Hong Jiang, Yuxuan Jiang, Ruiqing Chen, Qiongye Dong, Min Liao, Wanling Sun, Liqian Xu, Wei He, Zhenxing Guo
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Cell Death Discovery
Cell Death Discovery
DNA (cytosine-5)-methyltransferase 3A (DNMT3A) mutations occur in ~20% of de novo acute myeloid leukemia (AML) patients, and >50% of these mutations in AML samples are heterozygous missense alterations within the methyltransferase domain at residue R
Autor:
Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu, Yang Wu, Da-Xuan Tang, Fu-Chun Zhang, Meng Qiu, Qi Hua, Jing-Yu He, Jun Li, Bai Du, Ting-Hai Du, Lin-Lin Niu, Xue-Jun Jiang, Bo Cui, Jiang-Bin Chen, Yang-Gan Wang, Hai-Rong Wang, Qin Yu, Jing He, Yi-Lin Mao, Xiao-Fang Bin, Yue Deng, Yu-Dan Tian, Qing-Hua Han, Da-Jin Liu, Li-Qin Duan, Ming-Jun Zhao, Cui-Ying Zhang, Hai-Ying Dai, Ze-Hua Li, Ying Xiao, You-Zhi Hu, Xiao-Yu Huang, Kun Xing, Xin Jiang, Chao-Feng Liu, Jing An, Feng-Chun Li, Tao Tao, Jin-Fa Jiang, Ying Yang, Yao-Rong Dong, Lei Zhang, Guang Fu, Ying Li, Shu-Wei Huang, Li-Ping Dou, Lan-Jun Sun, Ying-Qiang Zhao, Jie Li, Yun Xia, Fan Liu, Wen-Jin He, Jian-Cong Tan, Yang Lin, Ya-Bin Zhou, Jian-Fei Yang, Guo-Qing Ma, Hui-Jun Chen, He-Ping Liu, Zong-Wu Liu, Jian-Xiong Liu, Xiao-Jia Luo, Xiao-Hong Bin, Ya-Nan Yu, Hai-Xia Dang, Bing Li, Fei Teng, Wang-Min Qiao, Xiao-Long Zhu, Bing-Wei Chen, Qi-Guang Chen, Chun-Ti Shen, Yong-Yan Wang, Yun-Dai Chen, Zhong Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-10 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart disease. Here, in an adaptive, 31-cente
Autor:
Ying-Ying Liang, Fei-Yu Niu, An-An Xu, Li-Li Jiang, Chun-shan Liu, Hui-ping Liang, Yu-Fan Huang, Xun-Fan Shao, Zhi-Wen Mo, Ya-Wei Yuan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-10 (2022)
Worldwide, nasopharyngeal carcinoma (NPC) is a rare head and neck cancer; however, it is a common malignancy in southern China. Radiotherapy is the most important treatment strategy for NPC. However, although radiotherapy is a strong tool to kill can
Autor:
Wenwen Xue, Xin Li, Wuhao Li, Yixuan Wang, Chengfei Jiang, Lin Zhou, Jian Gao, Ying Yu, Yan Shen, Qiang Xu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Loss-of-function mutations frequently occur in tumor suppressor genes, i.e., p53, during the malignant progression of various cancers. Whether any intrinsic suppressor carries a rare mutation is largely unknown. Here, we demonstrate that intracellula
Autor:
Yan Chen, Danqi Chen, Ying Qin, Cheng Qiu, Yaoyao Zhou, Mengmeng Dai, Lulu Li, Qinsheng Sun, Yuyang Jiang
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-10 (2022)
Cell Death Discovery
Cell Death Discovery
Colorectal cancer (CRC) is one of the digestive tract malignancies whose early symptoms are not obvious. This study aimed to identify novel targets for CRC therapy, especially early-stage CRC, by reanalyzing the publicly available GEO and TCGA databa
Autor:
Hui Zhao, Tie-Cheng Wang, Xiao-Feng Li, Na-Na Zhang, Liang Li, Chao Zhou, Yong-Qiang Deng, Tian-Shu Cao, Guan Yang, Rui-Ting Li, Yi-Jiao Huang, Yuan-Guo Li, Yi-Ming Zhang, Fang-Xu Li, Yu-Ren Zhou, Yu-Hang Jiang, Xi-Shan Lu, Shi-Hui Sun, Meng-Li Cheng, Kai-Ping Gu, Mei Zhang, Qing-Qing Ma, Xiao Yang, Bo Ying, Yu-Wei Gao, Cheng-Feng Qin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-9 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Messenger RNA (mRNA) vaccine technology has shown its power in preventing the ongoing COVID-19 pandemic. Two mRNA vaccines targeting the full-length S protein of SARS-CoV-2 have been authorized for emergency use. Recently, we have developed a lipid n
Autor:
Ying Zhang, Wenping Ma, Wenhua Fan, Changyuan Ren, Jianbao Xu, Fan Zeng, Zhaoshi Bao, Tao Jiang, Zheng Zhao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Glioma is the most common primary malignant brain tumor with limited treatment options and poor prognosis. To investigate the potential relationships between transcriptional characteristics and clinical phenotypes, we applied weighted gene co-express
Autor:
Jing Zhao, Han Xiao, Ping Liang, Ning Jiang, Li Zhang, Shuyue Zheng, Hui Gan, Xuan Zhai, Hui Chen, Lu Wang
Publikováno v:
Experimental and Molecular Medicine, Vol 53, Iss 11, Pp 1807-1818 (2021)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
The NLRC4 inflammasome, a member of the nucleotide-binding and oligomerization domain-like receptor (NLR) family, amplifies inflammation by facilitating the processing of caspase-1, interleukin (IL)–1β, and IL-18. We explored whether NLRC4 knockdo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Cetuximab is approved for the treatment of metastatic colorectal cancer (mCRC) with RAS wild-type. Nevertheless, the prognosis remains poor and the effectiveness of cetuximab is limited in KRAS mutant mCRC. Recently, emerging evidence has shown that