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Publikováno v:
Scientific Reports
Functional mouse double minute-2 (MDM2) promoter variants may alter MDM2 expression and thus affect radiotherapy response and prognosis of squamous cell carcinoma of oropharynx (SCCOP). Thus we assessed association of 2 functional MDM2 promoter varia
Autor:
Chey Loveday, Kerry Fenwick, Peter Broderick, Philip J. Law, Trine B. Haugen, Tom Grotmol, Giulia Orlando, Kevin Litchfield, D. Timothy Bishop, Zsofia Kote-Jarai, Gabriele Migliorini, Fredrik Wiklund, Amy Holroyd, Robert Huddart, Nora Pashayan, Wenche Kristiansen, Alison M. Dunning, Kenneth Muir, Robert Karlsson, Max Levy, Ioannis Assiotis, Jérémie Nsengimana, Nick Orr, Richard S. Houlston, Julian Peto, Clare Turnbull, Douglas F. Easton, Alison Reid, Rosalind A. Eeles, Darshna Dudakia, Janet Shipley
Publikováno v:
Nature Genetics
Litchfield, K, Levy, M, Orlando, G, Loveday, C, Law, P J, Migliorini, G, Holroyd, A, Broderick, P, Karlsson, R, Haugen, T B, Kristiansen, W, Nsengimana, J, Fenwick, K, Assiotis, I, Kote-Jarai, ZS, Dunning, A M, Muir, K R, Peto, J, Eeles, R, Easton, D F, Dudakia, D, Orr, N, Pashayan, N, Bishop, D T, Reid, A, Huddart, R A, Shipley, J, Grotmol, T, Wiklund, F, Houlston, R S, Turnbull, C & UK Testicular Cancer Collaboration 2017, ' Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ', Nature Genetics, vol. 49, no. 7, pp. 1133-1140 . https://doi.org/10.1038/ng.3896
Litchfield, K, Levy, M, Orlando, G, Loveday, C, Law, P J, Migliorini, G, Holroyd, A, Broderick, P, Karlsson, R, Haugen, T B, Kristiansen, W, Nsengimana, J, Fenwick, K, Assiotis, I, Kote-Jarai, Z, Dunning, A M, Muir, K, Peto, J, Eeles, R, Easton, D F, Dudakia, D, Orr, N, Pashayan, N, Bishop, D T, Reid, A, Huddart, R A, Shipley, J, Grotmol, T, Wiklund, F, Houlston, R S, Turnbull, C, UK Testicular Cancer Collaboration & The PRACTICAL Consortium 2017, ' Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ', Nature Genetics, vol. 49, no. 7, pp. 1133-1140 . https://doi.org/10.1038/ng.3896
Litchfield, K, Levy, M, Orlando, G, Loveday, C, Law, P J, Migliorini, G, Holroyd, A, Broderick, P, Karlsson, R, Haugen, T B, Kristiansen, W, Nsengimana, J, Fenwick, K, Assiotis, I, Kote-Jarai, ZS, Dunning, A M, Muir, K R, Peto, J, Eeles, R, Easton, D F, Dudakia, D, Orr, N, Pashayan, N, Bishop, D T, Reid, A, Huddart, R A, Shipley, J, Grotmol, T, Wiklund, F, Houlston, R S, Turnbull, C & UK Testicular Cancer Collaboration 2017, ' Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ', Nature Genetics, vol. 49, no. 7, pp. 1133-1140 . https://doi.org/10.1038/ng.3896
Litchfield, K, Levy, M, Orlando, G, Loveday, C, Law, P J, Migliorini, G, Holroyd, A, Broderick, P, Karlsson, R, Haugen, T B, Kristiansen, W, Nsengimana, J, Fenwick, K, Assiotis, I, Kote-Jarai, Z, Dunning, A M, Muir, K, Peto, J, Eeles, R, Easton, D F, Dudakia, D, Orr, N, Pashayan, N, Bishop, D T, Reid, A, Huddart, R A, Shipley, J, Grotmol, T, Wiklund, F, Houlston, R S, Turnbull, C, UK Testicular Cancer Collaboration & The PRACTICAL Consortium 2017, ' Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ', Nature Genetics, vol. 49, no. 7, pp. 1133-1140 . https://doi.org/10.1038/ng.3896
Genome-wide association studies (GWAS) have transformed understanding of susceptibility to testicular germ cell tumors (TGCTs), but much of the heritability remains unexplained. Here we report a new GWAS, a meta- A nalysis with previous GWAS and a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891cbe7c535fdd70cc54d2760339afa4
https://hdl.handle.net/10642/6047
https://hdl.handle.net/10642/6047
Autor:
Miguel González-Muñoz, Paolo Cipriani, Graham J. Pierce, Ivona Mladineo, Ivana Bušelić, Santiago Pascual, Norval J. C. Strachan, Miguel Bao, Simonetta Mattiucci
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
instname
Scientific Reports
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
17 páginas, 7 tablas, 4 figuras.-- This work is licensed under a Creative Commons Attribution 4.0 International License
Anisakiasis is an emerging zoonosis caused by the fish parasitic nematode Anisakis. Spain appears to have the highest report
Anisakiasis is an emerging zoonosis caused by the fish parasitic nematode Anisakis. Spain appears to have the highest report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfbf352f8468794ce53711cae97d6c7
http://hdl.handle.net/10261/147868
http://hdl.handle.net/10261/147868
Autor:
Kris A. Murray, Kevin J. Olival, Nathan Breit, Stephen Morse, Moreno Di Marco, Carlos Zambrana-Torrelio, Peter Daszak, Toph Allen, Carlo Rondinini
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Zoonoses originating from wildlife represent a significant threat to global health, security and economic growth, and combatting their emergence is a public health priority. However, our understanding of the mechanisms underlying their emergence rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9883bee3a5f68debcd84e22f2f2c9b7b
http://hdl.handle.net/11573/1087256
http://hdl.handle.net/11573/1087256
Publikováno v:
SCIENTIFIC REPORTS
Scientific reports, 7 (1
Scientific Reports
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific reports, 7 (1
Scientific Reports
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
To flexibly adapt to the demands of their environment, animals are constantly exposed to the conflict resulting from having to choose between predictably rewarding familiar options (exploitation) and risky novel options, the value of which essentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b197ee3c217f7df483b2faa988a64075
https://biblio.ugent.be/publication/8552704
https://biblio.ugent.be/publication/8552704
Autor:
Torben Hansen, Thorarinn Blondal, Anders Jakobsen, Sanne Kjær-Frifeldt, Jan Lindebjerg, S Morgenthaler, Flemming Brandt Sørensen, René dePont Christensen
Publikováno v:
British Journal of Cancer
Hansen, T F, Kjær-Frifeldt, S, Christensen, R D, Morgenthaler, S, Blondal, T, Lindebjerg, J, Sørensen, F B & Jakobsen, A 2014, ' Redefining high-risk patients with stage II colon cancer by risk index and microRNA-21: results from a population-based cohort ', B J C, bind 111, nr. 7, s. 1285-1292 . https://doi.org/10.1038/bjc.2014.409
Hansen, T F, Kjær-Frifeldt, S, Christensen, R D, Morgenthaler, S, Blondal, T, Lindebjerg, J, Sørensen, F B & Jakobsen, A 2014, ' Redefining high-risk patients with stage II colon cancer by risk index and microRNA-21: results from a population-based cohort ', British Journal of Cancer, vol. 111, no. 7, pp. 1285-1292 . https://doi.org/10.1038/bjc.2014.409
Hansen, T F, Kjær-Frifeldt, S, Christensen, R D, Morgenthaler, S, Blondal, T, Lindebjerg, J, Sørensen, F B & Jakobsen, A 2014, ' Redefining high-risk patients with stage II colon cancer by risk index and microRNA-21: results from a population-based cohort ', B J C, bind 111, nr. 7, s. 1285-1292 . https://doi.org/10.1038/bjc.2014.409
Hansen, T F, Kjær-Frifeldt, S, Christensen, R D, Morgenthaler, S, Blondal, T, Lindebjerg, J, Sørensen, F B & Jakobsen, A 2014, ' Redefining high-risk patients with stage II colon cancer by risk index and microRNA-21: results from a population-based cohort ', British Journal of Cancer, vol. 111, no. 7, pp. 1285-1292 . https://doi.org/10.1038/bjc.2014.409
BACKGROUND: The aim of the present study was to analyse the prognostic value of microRNA-21 (miRNA-21) in patients with stage II colon cancer aiming at a risk index for this group of patients.METHODS: A population-based cohort of 554 patients was inc
Autor:
C. La Vecchia, Maria Filomeno, Werner Garavello, Eva Negri, Fabio Levi, Cristina Bosetti, Carlotta Galeone
Publikováno v:
British Journal of Cancer
British Journal of Cancer, vol. 111, no. 5, pp. 981-986
British Journal of Cancer, vol. 111, no. 5, pp. 981-986
BACKGROUND: The Mediterranean diet has a beneficial role on various neoplasms, but data are scanty on oral cavity and pharyngeal (OCP) cancer. METHODS: We analysed data from a case-control study carried out between 1997 and 2009 in Italy and Switzerl
Publikováno v:
British Journal of Cancer
Background/Objective: Dietary patterns, which represent a complex integration of food and nutrients, have been used to explore the association between dietary factors and the risk of oesophageal cancer. However, the association remains unclear. This
Autor:
Young Hoon Kim, Youjin Je
Publikováno v:
British Journal of Cancer
Background: Experimental studies suggest potential anti-carcinogenic properties of vitamin D against breast cancer risk, but the epidemiological evidence to date is inconsistent. Methods: We searched MEDLINE and EMBASE databases along with a hand sea
Autor:
André, Romain, Elbaz, Meyer, Khalife, Khalife, Lim, Pascal, Ennezat, Pierre-Vladimir, Coste, Pierre, Le Breton, Hervé, Bataille, Vincent, Ferrières, Jean, Leusink, M, Onland-Moret, N, Asselbergs, F, Ding, B, Kotti, S, van Zuydam, N, Papp, A, Danchin, Nicolas, Donnelly, L, Morris, A, Chasman, D, Doevendans, P, Klungel, O, Ridker, P, van Gilst, W, Simon, Tabassome, Nyberg, F, Palmer, C, Sadee, W, van Der Harst, P, de Bakker, P, de Boer, A, Verstuyft, C, Maitland-van Der Zee, A
Publikováno v:
Clinical Pharmacology & Therapeutics, 95(3), 314-320. Nature Publishing Group
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 2013, 95 (2), pp.314-320. ⟨10.1038/clpt.2013.194⟩
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2013, 95 (2), pp.314-320. ⟨10.1038/clpt.2013.194⟩
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 2013, 95 (2), pp.314-320. ⟨10.1038/clpt.2013.194⟩
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2013, 95 (2), pp.314-320. ⟨10.1038/clpt.2013.194⟩
The association of nonfunctional variants of the cholesteryl ester transfer protein (CETP) with efficacy of statins has been a subject of debate. We evaluated whether three functional CETP variants influence statin efficacy. The effect of CETP genoty