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Autor:
Hu, Yuanyuan, Cronan, John E.
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Pimelic acid, a seven carbon α,ω-dicarboxylic acid (heptanedioic acid), is known to provide seven of the ten biotin carbon atoms including all those of the valeryl side chain. Distinct pimelate synthesis pathways were recently elucidated in Escheri
Autor:
João Mello-Vieira, Maria M. Mota, Vanessa Zuzarte-Luis, Tania F. de Koning-Ward, Francisco J. Enguita
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
© The Author(s) 2020. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriat
Genome of Solanum pimpinellifolium provides insights into structural variants during tomato breeding
Autor:
Zhangjun Fei, Lei Gao, Samantha Mainiero, Chen Jiao, James J. Giovannoni, Susan R. Strickler, Julia Vrebalov, Lukas A Mueller, Stefanos Stravoravdis, Xin Wang, Shan Wu, Carmen Catalá, Jing Zhang, Gregory B. Martin, Prashant S. Hosmani, Surya Saha
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Solanum pimpinellifolium (SP) is the wild progenitor of cultivated tomato. Because of its remarkable stress tolerance and intense flavor, SP has been used as an important germplasm donor in modern tomato breeding. Here, we present a high-quality chro
Autor:
Peter C. Fineran, Rafael Pinilla-Redondo, Robert D. Fagerlund, Chris M. Brown, Nicole D. Marino, Søren J. Sørensen, Saadlee Shehreen, Joseph Bondy-Denomy
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Pinilla-Redondo, R, Shehreen, S, Marino, N D, Fagerlund, R D, Brown, C M, Sørensen, S J, Fineran, P C & Bondy-Denomy, J 2020, ' Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements ', Nature Communications, vol. 11, 5652 . https://doi.org/10.1038/s41467-020-19415-3
Nature Communications
Pinilla-Redondo, R, Shehreen, S, Marino, N D, Fagerlund, R D, Brown, C M, Sørensen, S J, Fineran, P C & Bondy-Denomy, J 2020, ' Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements ', Nature Communications, vol. 11, 5652 . https://doi.org/10.1038/s41467-020-19415-3
Nature Communications
Many prokaryotes employ CRISPR–Cas systems to combat invading mobile genetic elements (MGEs). In response, some MGEs have developed strategies to bypass immunity, including anti-CRISPR (Acr) proteins; yet the diversity, distribution and spectrum of
Autor:
Thomas Obadia, Laurence Mousson, Basile Kamgang, Yoann Madec, Marie Vazeille, Chun-Hong Chen, Anna-Bella Failloux, Pei-Shi Yen, Lucy de Guilhem de Lataillade
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5801. ⟨10.1038/s41467-020-19625-9⟩
Nature Communications, 2020, 11 (1), pp.5801. ⟨10.1038/s41467-020-19625-9⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5801. ⟨10.1038/s41467-020-19625-9⟩
Nature Communications, 2020, 11 (1), pp.5801. ⟨10.1038/s41467-020-19625-9⟩
Historically endemic to Sub-Saharan Africa and South America, yellow fever is absent from the Asia-Pacific region. Yellow fever virus (YFV) is mainly transmitted by the anthropophilic Aedes mosquitoes whose distribution encompasses a large belt of tr
Autor:
Larry S. Barak, Richard A. Gibbs, Yushi Bai, Maria Kousi, Tanner O. Monroe, Karen Soldano, Jeremiah Savage, Sungjin Moon, Ramona M. Rodriguiz, Steven C. Brodar, Thomas Hansen, Melanie E. Garrett, Donna M. Muzny, Nicholas Katsanis, Akira Sawa, William C. Wetsel, Allison E. Ashley-Koch, Patrick F. Sullivan, Thomas Werge
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Monroe, T O, Garrett, M E, Kousi, M, Rodriguiz, R M, Moon, S, Bai, Y, Brodar, S C, Soldano, K L, Savage, J, Hansen, T F, Muzny, D M, Gibbs, R A, Barak, L, Sullivan, P F, Ashley-Koch, A E, Sawa, A, Wetsel, W C, Werge, T & Katsanis, N 2020, ' PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia ', Nature Communications, vol. 11, no. 1, 5903 . https://doi.org/10.1038/s41467-020-19637-5
Nature Communications
Monroe, T O, Garrett, M E, Kousi, M, Rodriguiz, R M, Moon, S, Bai, Y, Brodar, S C, Soldano, K L, Savage, J, Hansen, T F, Muzny, D M, Gibbs, R A, Barak, L, Sullivan, P F, Ashley-Koch, A E, Sawa, A, Wetsel, W C, Werge, T & Katsanis, N 2020, ' PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia ', Nature Communications, vol. 11, no. 1, 5903 . https://doi.org/10.1038/s41467-020-19637-5
Nature Communications
The neuronal primary cilium and centriolar satellites have functions in neurogenesis, but little is known about their roles in the postnatal brain. We show that ablation of pericentriolar material 1 in the mouse leads to progressive ciliary, anatomic
Autor:
Mary Ziegler, Katrina M. Welch-Reardon, Nathan N. Shon, Jennifer S. Fang, Nan W. Hultgren, Duc T. T. Phan, Antonio E. Paniagua, Ali Mortazavi, Ricardo Ramirez, Christopher C.W. Hughes, Lin S. Kim, Michaela M.S. Hatch, David S. Williams
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Slug (SNAI2), a member of the well-conserved Snail family of transcription factors, has multiple developmental roles, including in epithelial-to-mesenchymal transition (EMT). Here, we show that Slug is critical for the pathological angiogenesis neede
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
The mechanism and function of autophagy as a highly-conserved bulk degradation pathway are well studied, but the physiological role of autophagy remains poorly understood. We show that autophagy is involved in the adaptation of Saccharomyces cerevisi
Autor:
Radu Cojocaru, Anatoly N. Kravetz, Daniela Cristea, Jean Rauzier, Clifford G. Clark, Olivier Gascuel, Marie-Laure Quilici, François-Xavier Weill, Elisabeth Njamkepo, Adriana Simona Ciontea, Monakhova Ev, Maria Damian, Mihaela Oprea, Anna Zhukova
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5347. ⟨10.1038/s41467-020-19185-y⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5347. ⟨10.1038/s41467-020-19185-y⟩
Nature Communications
Nature Communications, 2020, 11 (1), pp.5347. ⟨10.1038/s41467-020-19185-y⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5347. ⟨10.1038/s41467-020-19185-y⟩
In 1970, the seventh pandemic of cholera (7 P) reached both Africa and Europe. Between 1970 and 2011, several European countries reported cholera outbreaks of a few to more than 2,000 cases. We report here a whole-genome analysis of 1,324 7 P V. chol
Autor:
Xuejiang Gu, Xinjie Zhao, Shenghan Lai, Guixue Hou, Yixuan Qiu, Huanzi Zhong, Ping Kong, Huahui Ren, Jialin Yang, Yongde Peng, Shan Huang, Zhun Shi, Yanyun Gu, Guowang Xu, Guang Ning, Shen Qu, Junhua Li, Yifei Zhang, Li Chen, Qin Huang, Yaoming Xue, Li Qin, Xiaolin Wang, Qi Li, Mengyu Gao, Jing Ma, Li Xuelin, Gang Chen, Huanming Yang, Weiqing Wang, Shujie Wang, Yuanqiang Zou, Jian Wang, Jun Liang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeostasis. We hence conducted a randomized,