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Autor:
Chuanjuan Tao, Xiaoxu Li, Steffen Jockusch, Irina Morozova, Shiv Kumar, Minchen Chien, Sergey Kalachikov, James J. Russo, Jingyue Ju
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
SARS-CoV-2 is responsible for COVID-19, resulting in the largest pandemic in over a hundred years. After examining the molecular structures and activities of hepatitis C viral inhibitors and comparing hepatitis C virus and coronavirus replication, we
Autor:
Tobias Junt, Gieri Cathomas, Kirsten D. Mertz, Viktor H. Koelzer, Holger Moch, Francesca Demichelis, Thomas Hoyler, Alexandar Tzankov, Nathalie Schwab, Niels Willi, Maurice Henkel, Werner Kempf, Angela Frank, Ronny Nienhold, Thomas Menter, Markus Tolnay, Veronika Zsikla, Mattia Barbareschi, Jasmin D. Haslbauer, Yari Ciani
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Coronavirus Disease 19 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has grown to a worldwide pandemic with substantial mortality. Immune mediated damage has been proposed as a patho
Autor:
Noorjahan Banu Alitheen, Sook Yee Boo, Swee Keong Yeap, Abdul Rahman Omar, Chai Ling Ho, Sheau Wei Tan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The infectious bursal disease (IBD) is an acute immunosuppressive viral disease that significantly affects the economics of the poultry industry. The IBD virus (IBDV) was known to infect B lymphocytes and activate macrophage and T lymphocytes, but th
Autor:
Ibrahim R. Baiuomy, Marwa A. EL-Dardiry, Mona M. Mohammed, Abd El-Hamid A. Sabry, Kamal El-Din M. Mokbel
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Schistosomiasis is a serious parasitic infection affecting millions worldwide. This study aimed to explore the anti-schistosomal activity of curcumin and curcumin loaded gold-nanoparticles (Cur-GNPs) with or without praziquantel (PZQ). We used six gr
Autor:
Wandee Yindeeyoungyeon, Erngsiri Kaewkhunjob, Chitsuda Pongma, Tanapat Palaga, Anumart Buakeaw, Songchan Puthong, Songkiat Songthammanuphap, Saradee Warit, Therdsak Prammananan, Wanlaya Tipkantha
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Tuberculosis is highly contagious disease that can be transmitted between humans and animals. Asian elephants (Elephas maximus) in captivity live in close contact with humans in many Asian countries. In this study, we developed an interferon gamma re
Autor:
Larissa M. N. Pereira, Katherine A. Fitzgerald, Caroline Junqueira, Patricia A. Assis, Ricardo T. Gazzinelli, Dario S. Zamboni, Dhelio Batista Pereira, Natalia M. de Araujo, Danielle Fernandes Durso, Egil Lien, Douglas T. Golenbock, Marco Antonio Ataide
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Communications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Communications
Earlier studies indicate that either the canonical or non-canonical pathways of inflammasome activation have a limited role on malaria pathogenesis. Here, we report that caspase-8 is a central mediator of systemic inflammation, septic shock in the Pl
Autor:
Hao Wu, Taobin Chen, Zenghao Yan, Zhang Weijian, Shuo Chen, Haokui Zhou, Hongliang Yao, Weiwei Su, Yan He
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Naoxintong Capsule (NXT) is a Traditional Chinese Medicine formulation which has been widely applied in treating cardiovascular and cerebrovascular diseases. Previous studies also reported the potential effects of NXT against diabetes and certain com
Autor:
Zheng Zhao, Yanwei Liu, Rui-Chao Chai, Yinyuan Wang, Tao Jiang, Kaijia Zhou, Guanzhang Li, Lijie Huang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Glioma is the most common primary intracranial tumor and is associated with very low survival rates. The development of reliable biomarkers can help to elucidate the molecular mechanisms involved in glioma development. Here the expression of ABCC8 mR
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Eosinophilic bronchitis (EB) is a clinical disease characterized by chronic cough, airway eosinophil infiltration, and responsive to steroid therapy but with the absence of airway hyperreactivity (AHR). This study established an EB mouse model with a
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Cryptococcal meningitis is the most common intracranial infectious fungal disease. After a period of antifungal treatment, as the number of cells in the cerebrospinal fluid decreases, the biochemical indexes improve and the number of cryptococcus red