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Autor:
Inge Mannaerts, Ricard Farré, Olivier Govaere, Mathias Wenes, Petra Windmolders, Sabine Klein, Leo A. van Grunsven, Len Verbeke, Ingrid Vander Elst, Wim Laleman, Massimiliano Mazzone, Jonel Trebicka, Frederik Nevens, Robert Schierwagen
Publikováno v:
Scientific Reports
Hepatic inflammation drives hepatic stellate cells (HSC), resulting in liver fibrosis. The Farnesoid-X receptor (FXR) antagonizes inflammation through NF-κB inhibition. We investigated preventive and therapeutic effects of FXR agonist obeticholic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf4e9af910a7f53cd0eb80d20fe7024
https://hdl.handle.net/20.500.14017/1fce66a1-b0d7-4666-866c-3092ac73fa46
https://hdl.handle.net/20.500.14017/1fce66a1-b0d7-4666-866c-3092ac73fa46
Autor:
Catrysse, L, Farhang Ghahremani, M, Vereecke, L, Youssef, S A, Mc Guire, C, Sze, M, Weber, A, Heikenwalder, M, de Bruin, A, Beyaert, R, van Loo, G, LS Pathobiologie, Regenerative Medicine, Stem Cells & Cancer, dPB RMSC
Publikováno v:
Cell death & disease, 7(6). Nature Publishing Group
Cell death & disease, 7:2250. Nature Publishing Group
Cell Death & Disease
CELL DEATH & DISEASE
Cell death & disease, 7:2250. Nature Publishing Group
Cell Death & Disease
CELL DEATH & DISEASE
An important regulator of inflammatory signalling is the ubiquitin-editing protein A20 that acts as a break on nuclear factor-κB (NF-κB) activation, but also exerts important cytoprotective functions. A20 knockout mice are cachectic and die prematu
Recent evidence shows that cultured mycelium Cordyceps sinensis (CMCS) effectively protects against liver fibrosis in mice. Here, we investigated whether the anti-fibrotic action of CMCS was related to its regulation of the activity of hepatic natura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb2b1671cfd7699c6478e66ed31938a
https://europepmc.org/articles/PMC4753371/
https://europepmc.org/articles/PMC4753371/