Zobrazeno 1 - 10
of 371
pro vyhledávání: ''
Autor:
Bin Li, Zhihai Peng, Huamei Tang, Dan Li, Xueni Liu, Hongze Sun, Qianlan Yao, Xiaole Meng, Zhongyi Ding, Xiao Peng, Fangming Zhu, Xisheng Liu, Ying Lu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Increasing evidence suggests that global downregulation of miRNA expression is a hallmark of human cancer, potentially due to defects in the miRNA processing machinery. In this study, we found that the protein expression of Argonaute 2 (AGO2), a key
Autor:
Tong Shen, Youlutuziayi Rixiati, Ling-Dong Cai, Jian-Ming Li, Jing-Lin Liu, Chu-Yi Wang, Yuan-Yuan Zhao, Shi Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-18 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
The mechanisms and key factors involved in tumor environments for lung metastasis of CRC are still unclear. Here, using clinical samples from lung metastases of CRC patients, we found that intestinal immune network for IgA production was significantl
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 3, Pp 1-10 (2021)
Blood Cancer Journal
Blood Cancer Journal
Immunotherapy has shown efficacy in relapsed multiple myeloma (MM). However, these therapies may depend on a functional tumor immune microenvironment (iTME) for their efficacy. Characterizing the evolution of the iTME over the disease course is neces
Autor:
Lianpeng Chang, Xin Yi, Xuefeng Xia, Ming Chen, Yanfang Guan, Zhipeng Zhou, Pansong Li, Ling Yang, Rongrong Chen, Zhengbo Song, Yiping Zhang, Guoping Cheng, Wenxian Wang, Rongrong Zhou
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Brain metastasis (BM) is a common malignant event in lung cancer. Here, we recruited 33 lung cancer patients with brain oligo-metastasis to explore the genomic features and tumor immune microenvironment (TIME) of the lung and BM independently. For ge
Role of Sciellin in gallbladder cancer proliferation and formation of neutrophil extracellular traps
Autor:
Huijie Miao, Yingbin Liu, Liguo Liu, Yang Li, Yijian Zhang, Yongsheng Li, Yang Yang, Yunping Hu, Qindie Xu, Tai Ren, Bo Yang, Chen Cai, Ruiyan Yuan, Chengkai Jiang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Apart from primary tumor development and metastasis, cancer-associated thrombosis is the second cause of cancer death in solid tumor malignancy. However, the mechanistic insight into the development of gallbladder cancer (GBC) and cancer-associated t
Autor:
Qinfeng Mu, Jun Zhang, Ying Zhou, Haixiang Xue, Tongbing Chen, Jisheng Liu, Miaomei Yu, Guanghua Luo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Prior studies have shown that apolipoprotein M (APOM) is involved in the development of some cancers. Here we investigated the effects of APOM on larynx cancer (LC). 20 patients with vocal cord polyps and 18 patients with LC were included in this stu
Autor:
Fang Li, Fang Lv, Xingkai Li, Kun Yang, Xuezhi Hao, Yicheng Liang, Hengqi Chen, Bing Wang, Yushun Gao
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Numerous studies have reported the association of long non-coding RNAs (lncRNAs) in cancers, yet the function of lncRNA high expressed in hepatocellular carcinoma (HEIH) in esophageal carcinoma (EC) has seldom been explored. Here, we aimed to explore
Autor:
Maria C. Basil, Susan M. Lin, Jilly F. Evans, Edward E. Morrisey, Justine Carl, Aravind Sivakumar, Ryan Rue, Shanru Li, Michael Morley, Andrei I. Gritsiuta, Kseniya Obraztsova, Jeremy Katzen, David B. Frank, Edward Cantu, Annette Robichaud, Vera P. Krymskaya, Apoorva Babu, Alexander R. Mukhitov, Elena N. Atochina-Vasserman, Michael F. Beers, Meghan Kopp
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Lymphangioleiomyomatosis (LAM) is a rare fatal cystic lung disease due to bi-allelic inactivating mutations in tuberous sclerosis complex (TSC1/TSC2) genes coding for suppressors of the mechanistic target of rapamycin complex 1 (mTORC1). The origin o
Autor:
Peter Bergman, Laia Gorchs, Alisa Knauf, Elena Rangelova, Rainer Heuchel, Chanté Mayer, Sultan Ahmed, Mattias Svensson, Carlos Fernández Moro, Helen Kaipe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
The pancreatic tumour stroma is composed of phenotypically heterogenous cancer-associated fibroblasts (CAFs) with both pro- and anti-tumorigenic functions. Here, we studied the impact of calcipotriol, a vitamin D3 analogue, on the activation of human
Autor:
Wu Zhong, Zhihong Wu, Yingmei Feng, Jie Ma, Yunping Zhu, Danlei Mou, Ling Leng, Luye Lv, Zhongjie Hu, Hongjun Li, Feng Gong, Jiang Zhao, Shikun Zhang, Wei Li, Ruiyuan Cao, Yan Dai, Haiping Xiang, Lei Zhao, Bintao Qiu, Dunqin Gao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-9 (2020)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
The COVID-19 pandemic has emerged as a global health emergency due to its association with severe pneumonia and relative high mortality. However, the molecular characteristics and pathological features underlying COVID-19 pneumonia remain largely unk