Zobrazeno 1 - 10
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pro vyhledávání: ''
Autor:
Bin Li, Zhihai Peng, Huamei Tang, Dan Li, Xueni Liu, Hongze Sun, Qianlan Yao, Xiaole Meng, Zhongyi Ding, Xiao Peng, Fangming Zhu, Xisheng Liu, Ying Lu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Increasing evidence suggests that global downregulation of miRNA expression is a hallmark of human cancer, potentially due to defects in the miRNA processing machinery. In this study, we found that the protein expression of Argonaute 2 (AGO2), a key
Autor:
Lianpeng Chang, Xin Yi, Xuefeng Xia, Ming Chen, Yanfang Guan, Zhipeng Zhou, Pansong Li, Ling Yang, Rongrong Chen, Zhengbo Song, Yiping Zhang, Guoping Cheng, Wenxian Wang, Rongrong Zhou
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Brain metastasis (BM) is a common malignant event in lung cancer. Here, we recruited 33 lung cancer patients with brain oligo-metastasis to explore the genomic features and tumor immune microenvironment (TIME) of the lung and BM independently. For ge
Role of Sciellin in gallbladder cancer proliferation and formation of neutrophil extracellular traps
Autor:
Huijie Miao, Yingbin Liu, Liguo Liu, Yang Li, Yijian Zhang, Yongsheng Li, Yang Yang, Yunping Hu, Qindie Xu, Tai Ren, Bo Yang, Chen Cai, Ruiyan Yuan, Chengkai Jiang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Apart from primary tumor development and metastasis, cancer-associated thrombosis is the second cause of cancer death in solid tumor malignancy. However, the mechanistic insight into the development of gallbladder cancer (GBC) and cancer-associated t
Autor:
Fang Li, Fang Lv, Xingkai Li, Kun Yang, Xuezhi Hao, Yicheng Liang, Hengqi Chen, Bing Wang, Yushun Gao
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Numerous studies have reported the association of long non-coding RNAs (lncRNAs) in cancers, yet the function of lncRNA high expressed in hepatocellular carcinoma (HEIH) in esophageal carcinoma (EC) has seldom been explored. Here, we aimed to explore
Autor:
Peter Bergman, Laia Gorchs, Alisa Knauf, Elena Rangelova, Rainer Heuchel, Chanté Mayer, Sultan Ahmed, Mattias Svensson, Carlos Fernández Moro, Helen Kaipe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
The pancreatic tumour stroma is composed of phenotypically heterogenous cancer-associated fibroblasts (CAFs) with both pro- and anti-tumorigenic functions. Here, we studied the impact of calcipotriol, a vitamin D3 analogue, on the activation of human
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-16 (2020)
Cell Death & Disease
Cell Death & Disease
Androgen receptor (AR) signaling is a major driver of prostate cancer (CaP). Although most therapies targeting AR are initially effective in CaP patients, drug resistance is inevitable, mainly because of the inappropriate re-activation of AR pathway.
Autor:
Huijuan Wu, Hongbo Wu, Lijuan Chen, Xiufeng Hu, Yu Mu, Fangfang Yuan, Lei Liu, Wenjing Liu, Xiaoqian Mu, Jie Liu, Yanqiu Zhao
Publikováno v:
Cell Death and Disease, Vol 11, Iss 9, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Exosomes are small endogenous membrane vesicles that can mediate cell communication by transferring genetic materials. Based on that, exosomes have always been discussed as a cargo carrier for microRNA (miRNA) transportation. Accumulating data have r
Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients
Autor:
Chang Gok Woo, Hyo Yung Yun, Hee Kyung Kim, Su-Hyung Park, Seung Myoung Son, Hyung-Don Kim, Jihyun Kwon, June Young Koh, Hongsik Kim, Tae Yong Kim, Minsuk Kwon, Hye Sook Han, Yaewon Yang, Dae Hoon Kim, Eui-Cheol Shin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
This study compared the tumor immune microenvironments (TIMEs) of primary gastric cancer (PGC) and paired metastatic gastric cancer (MGC). CD4+ and CD8+ T-cell density and PD-L1 expression were evaluated by multiplex immunohistochemistry, DNA mismatc
Publikováno v:
Cell Death and Disease, Vol 11, Iss 7, Pp 1-15 (2020)
Cell Death & Disease
Cell Death & Disease
The excessive activation and proliferation of lung fibroblasts are responsible for the abundant deposition of extracellular matrix (ECM) in idiopathic pulmonary fibrosis (IPF), while its specific mechanism is still unknown. This study focuses on the
Autor:
Yabo Ouyang, Dexi Chen, Lijun Pang, Xianghua Guo, Ronghua Jin, Jiming Yin, Ying-Mei Feng, Hongbo Shi, Honglin Shi, Wenjing Wang, Luxin Qiao
Publikováno v:
Cell Death and Disease, Vol 11, Iss 6, Pp 1-8 (2020)
Cell Death & Disease
Cell Death & Disease
Background: Although most patients with COVID-19 pneumonia have a good prognosis, some patients develop to severe or critical cases, and the mortality of critical cases was up to 61.5%. However, specific information and molecular mechanism about crit