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Autor:
Fang-Ju Lin, Corey J. Langer, Teng Jin Ong, Yin Wan, Scott Whiting, Marc F. Botteman, Markus F. Renschler, Vera Hirsh, Isamu Okamoto
Publikováno v:
British Journal of Cancer
Background: This analysis compared the quality-adjusted survival and clinical outcomes of albumin-bound paclitaxel+carboplatin (nab-PC) vs solvent-based paclitaxel+carboplatin (sb-PC) as first-line therapy in advanced non-small-cell lung cancer (NSCL
Autor:
Francesco Grossi, Julia Grigorieva, G. Burrafato, Claudio Sini, Carlo Genova, Heinrich Roder, Joanna Roder, Giulia Barletta, Claudia Maggioni, M.G. Dal Bello, Erika Rijavec, Krista Meyer, Federica Biello
Publikováno v:
British Journal of Cancer
Background: VeriStrat is a blood-based proteomic test with predictive and prognostic significance in second-line treatments for non-small cell lung cancer (NSCLC). This trial was designed to investigate the role of VeriStrat in first-line treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd01f1f77d4de787ebdefff22bd12ef
http://hdl.handle.net/11567/1023820
http://hdl.handle.net/11567/1023820
Autor:
Sebastian Stintzing, Rüdiger P. Laubender, Clemens Giessen, Andreas Schalhorn, L. Fischer von Weikersthal, Dominik Paul Modest, Christoph Schulz, Volker Heinemann
Publikováno v:
British Journal of Cancer
Background: Liver-limited disease (LLD) denotes a specific subgroup of metastatic colorectal cancer (mCRC) patients. Patients and Methods: A total of 479 patients with unresectable mCRC from an irinotecan-based randomised phase III trial were evaluat
Autor:
Christina Piperi, M Sakalidou, Penelope Korkolopoulou, Elias A. El-Habr, Christos Adamopoulos, Angelica A. Saetta, Efstratios Patsouris, Efstathios I. Boviatsis, Marios Themistocleous, George Vrettakos, Paraskevi Fragkou, Georgia Levidou, Kalliopi Petraki, Vassilis Samaras, Athanasios Zisakis, Ilenia Chatziandreou
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2013, 108 (10), pp.2142-2152. ⟨10.1038/bjc.2013.176⟩
British Journal of Cancer, 2013, 108 (10), pp.2142-2152. ⟨10.1038/bjc.2013.176⟩
British Journal of Cancer, Cancer Research UK, 2013, 108 (10), pp.2142-2152. ⟨10.1038/bjc.2013.176⟩
British Journal of Cancer, 2013, 108 (10), pp.2142-2152. ⟨10.1038/bjc.2013.176⟩
International audience; Background: Sox11 is a transcription factor expressed in foetal and neoplastic brain tissue, including gliomas. It has been shown to suppress the tumourigenicity of glioma stem cells in vivo, thereby being hypothesised to func
Autor:
Bassel F. El-Rayes, Cynthia Timmers, John L. Marshall, Tanios Bekaii-Saab, Shubham Pant, Santiago Aparo, Sanaa Tahiri, Sameh Mikhail, Susan Geyer, Miguel A. Villalona-Calero, Kristen K. Ciombor, Gregory B. Lesinski, Anne M. Noonan, Daniel H. Ahn, Thomas A. Mace, Christina Wu, James A. Zwiebel, Jennifer Sexton, Matthew R. Farren, Ying Huang
Pelareorep causes oncolysis in tumor cells with activated Ras. We hypothesized that pelareorep would have efficacy and immunomodulatory activity in metastatic pancreatic adenocarcinoma (MPA) when combined with carboplatin and paclitaxel. A randomized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5664a825b37cb0ceef2a9190140006fe
https://europepmc.org/articles/PMC4923331/
https://europepmc.org/articles/PMC4923331/
Autor:
Masaki Inoue, Satoru Kyo, Yoshiko Maida, Satoshi Ohno, Manabu Hashimoto, Masahiro Takakura, Tohru Kiyono, Noriko Mori, Nakamura Masahito, Yasunari Mizumoto
Publikováno v:
British Journal of Cancer
Background: Disabled phosphatidylinositol 3-kinase (PI3K)/AKT and mitogen-activated protein kinase/extracellular signal-regulated kinase signalling is involved in endometrial carcinogenesis, and there is evidence that expression of epidermal growth f
Autor:
Jiro Fujimoto, Eriko Sato, Hiroshi Toyoki, Syed Mahfuzul Alam, Teruhiko Tamaya, Israt Jahan, Hideki Sakaguchi
Publikováno v:
British Journal of Cancer
Angiogenesis is essential for development, growth and advancement of solid tumours. Interferon-gamma-inducible protein 10 (IP-10) regulates lymphocyte chemotaxis, mediates vascular pericyte proliferation and acts as an angiostatic agent, thus inhibit
Autor:
F Recchia, Paolo Carlini, L. Doni, Rodolfo Mattioli, E Barletta, Paolo Tralongo, Luca Moscetti, Bruno Massidda, Silvia Gasperoni, F. Di Costanzo, A. Iop
Publikováno v:
British Journal of Cancer
This study was performed to determine the activity of adding continuous infusion (CI) of 5-fluorouracil (5-FU) to gemcitabine (GEM) vs GEM alone in advanced pancreatic cancer (APC). In all, 94 chemo-naïve patients with APC were randomised to receive
Autor:
Jens O. Andersen, Jens Overgaard, Carsten Rose, Peter A. Andreasen, Flemming Brandt Sørensen, Ann Knoop, Steinbjørn Hansen, Anne Vibeke Lænkholm
Publikováno v:
British Journal of Cancer
Hansen, S, Overgaard, J, Rose, C, Knoop, A, Lænkholm, A-V, Andersen, J, Sørensen, F B & Andreasen, P 2003, ' Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients ', B J C, vol. 88, no. 1, pp. 102-108 . https://doi.org/10.1038/sj.bjc.6600662
Hansen, S, Overgaard, J, Rose, C, Knoop, A, Laenkholm, A-V, Andersen, J, Sørensen, F B & Andreasen, P A 2003, ' Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients ', British Journal of Cancer, vol. 88, no. 1, pp. 102-108 . https://doi.org/10.1038/sj.bjc.6600662
Hansen, S, Overgaard, J, Rose, C, Knoop, A, Lænkholm, A-V, Andersen, J, Sørensen, F B & Andreasen, P 2003, ' Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients ', B J C, vol. 88, no. 1, pp. 102-108 . https://doi.org/10.1038/sj.bjc.6600662
Hansen, S, Overgaard, J, Rose, C, Knoop, A, Laenkholm, A-V, Andersen, J, Sørensen, F B & Andreasen, P A 2003, ' Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients ', British Journal of Cancer, vol. 88, no. 1, pp. 102-108 . https://doi.org/10.1038/sj.bjc.6600662
Tumour angiogenesis and the levels of plasminogen activator inhibitor type 1 (PAI-1) are both informative prognostic markers in breast cancer. In cell cultures and in animal model systems, PAI-1 has a proangiogenic effect. To evaluate the interrelati
Autor:
Jennifer Treleaven, R. L. Powles, Jayesh Mehta, Radovan Saso, Bhawna Sirohi, Clive Horton, Samar Kulkarni, Claudius Rudin, Seema Singhal, A Rigg
Publikováno v:
British Journal of Cancer
We correlated age and body surface area corrected glomerular filtration rate (GFR) at the time of high-dose melphalan (HDM) administration with treatment-related toxicity (TT), time to disease progression and survival. Between 8/85 and 6/98, 144 newl