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pro vyhledávání: ''
Autor:
Ryul Kim, Sung Soo Yoon, Keonyong Lee, Nam Hoon Kwon, Yoosik Kim, Sunghoon Kim, Youngil Koh, Namseok Lee, Min A. Kim, Daeyoon Kim, Seulki Song, Dongchan Kim, Jayoung Ku
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Communications Biology
Communications biology, vol 3, iss 1
Communications Biology
Communications biology, vol 3, iss 1
Aminoacyl-tRNA synthetase-interacting multifunctional protein 2 (AIMP2) is a non-enzymatic component required for the multi-tRNA synthetase complex. While exon 2 skipping alternatively spliced variant of AIMP2 (AIMP2-DX2) compromises AIMP2 activity a
Autor:
Johannes H. Dreyer, Maike Büttner-Herold, Laura Werner, Ulrike Grittner, Gerald Niedobitek, David Hartmann, Mário Henrique M. Barros
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Commonly attributed to the prevalence of M2 macrophages, tumor-associated macrophages (TAM) are linked to poor outcome in Hodgkin lymphoma (HL). MYC is supposed to control the expression of M2-specific genes in macrophages, and deficiency in MYC-posi
Autor:
Marina Teresita Isla Larrain, Mariela A. Moreno Ayala, Matías Luis Pidre, Mercedes Imsen, Alejandro Javier Nicola Candia, Adriana Seilicovich, Antonela Sofía Asad, María Florencia Gottardo, Marianela Candolfi, Víctor Romanowski, Camila Florencia Zuccato, Aldo Creton
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Humanin (HN) is a mitochondrial-derived peptide with cytoprotective efect in many tissues. Administration of HN analogs has been proposed as therapeutic approach for degenerative diseases. Although HN has been shown to protect normal tissues from che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b848c8091c7aa5faf04586caf8b6935
https://www.nature.com/articles/s41598-020-65381-7
https://www.nature.com/articles/s41598-020-65381-7
Autor:
Lars Bullinger, Nádia C. Correia, Michael Seifert, Andreas Trumpp, Anna Dolnik, Michael A. Rieger, Ingo Roeder, Chris Lauber
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Acute myeloid leukemia (AML) is a very heterogeneous and highly malignant blood cancer. Mutations of the DNA methyltransferase DNMT3A are among the most frequent recurrent genetic lesions in AML. The majority of DNMT3A-mutant AML patients shows fast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cbdfac4d3077175f91f70882a32b86
http://edoc.mdc-berlin.de/20039/1/20039oa.pdf
http://edoc.mdc-berlin.de/20039/1/20039oa.pdf
Autor:
Stefan K. Bohlander, Stephanie Schneider, Bernhard Wörmann, Marion Subklewe, Utz Krug, Tobias Herold, Victoria V. Grunwald, Wolfgang Hiddemann, Klaus H. Metzeler, Dennis Goerlich, Maria Cristina Sauerland, Andreas Faldum, Hanna Janke, Philipp A. Greif, Michaela Neusser, Karsten Spiekermann, Nikola P. Konstandin, Bianka Ksienzyk, Jan Braess, Maja Rothenberg-Thurley, Wolfgang E. Berdel, Annika Dufour
Publikováno v:
Leukemia 34, 3161–3172 (2020)
Leukemia
Leukemia
The revised 2017 European LeukemiaNet (ELN) recommendations for genetic risk stratification of acute myeloid leukemia have been widely adopted, but have not yet been validated in large cohorts of AML patients. We studied 1116 newly diagnosed AML pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7a029aec149d838a66c6422a8aa8e7
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58756
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58756
Autor:
Ava Kwong, Maribel D Lacambra, Michelle A. Lee, Julia Y S Tsang, Cherry Wu, Sai-Yin Cheung, Yun-Bi Ni, Gary Tse, Yau-Kam Hui
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Phyllodes tumor (PT) of the breast is a rare but clinically important fibroepithelial tumor with potential risks of recurrence and metastasis. Recent studies identified recurrent TERT promoter mutations in PTs. However, the clinical significance of t
Publikováno v:
British Journal of Cancer
Background: Indeterminate pulmonary nodules in patients diagnosed with osteosarcoma present a challenge for accurate staging and prognosis. The aim of this study was to explore the significance of this finding. Methods: A retrospective cohort study o
Autor:
Nolan B. Condron, Michael A. Liu, Jane A. Driver, Gregory A. Abel, Martha Wadleigh, Tammy T. Hshieh
Publikováno v:
British Journal of Cancer
Background: Few studies have investigated the relationship between physician and patient-assessed performance status (PS) in blood cancers. Methods: Retrospective analysis among 1418 patients with haematologic malignancies seen at Dana-Farber Cancer
Autor:
Hoguen Kim, Sang Joon Shin, Nam Kyu Kim, Su Jin Heo, Joo Hoon Kim, Minkyu Jung, Joong Bae Ahn, Jee Hung Kim, Hyung Soon Park, Chan Kim, Chang Gon Kim, Byung Soh Min, Woong Sub Koom, Seung Hoon Beom
Publikováno v:
British Journal of Cancer
Background: Among colorectal cancers (CRCs), high-frequency microsatellite instability (MSI-H) is associated with a better prognosis, compared with low-frequency MSI or microsatellite stability (MSI-L/MSS). However, it is unclear whether MSI affects
Autor:
Thomas Hermanns, Sophia Sander, Joerg Beyer, Oliver Gross, Lisa Roth, Christian D. Fankhauser, Tullio Sulser, Burkhardt Seifert, Daniel Eberli
Publikováno v:
British Journal of Cancer
Fankhauser, Christian Daniel; Sander, Sophia; Roth, Lisa; Gross, Oliver; Eberli, Daniel; Sulser, Tullio; Seifert, Burkhardt; Beyer, Jörg; Hermanns, Thomas (2018). Systemic inflammatory markers have independent prognostic value in patients with metastatic testicular germ cell tumours undergoing first-line chemotherapy. British journal of cancer, 118(6), pp. 825-830. Nature Publishing Group 10.1038/bjc.2017.467
Fankhauser, Christian Daniel; Sander, Sophia; Roth, Lisa; Gross, Oliver; Eberli, Daniel; Sulser, Tullio; Seifert, Burkhardt; Beyer, Jörg; Hermanns, Thomas (2018). Systemic inflammatory markers have independent prognostic value in patients with metastatic testicular germ cell tumours undergoing first-line chemotherapy. British journal of cancer, 118(6), pp. 825-830. Nature Publishing Group 10.1038/bjc.2017.467
BACKGROUND The prognostic utility of systemic inflammatory markers has so far not been investigated in patients with metastatic testicular germ cell tumours (GCTs). METHODS International Germ Cell Cancer Cooperative Group (IGCCCG) risk groups and blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd85893c88e7ff55d3d80f5322a81258