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of 55
pro vyhledávání: ''
Autor:
Géraldine Pignot, Nicolas Barry Delongchamps, Anne Schnitzler, Diane Damotte, Michaël Peyromaure, Constance Le Goux, Mathilde Sibony, Yves Allory, Marc Zerbib, Sophie Vacher, Ivan Bièche
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.16641. ⟨10.1038/s41598-020-73642-8⟩
Scientific Reports, 2020, 10 (1), pp.16641. ⟨10.1038/s41598-020-73642-8⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.16641. ⟨10.1038/s41598-020-73642-8⟩
Scientific Reports, 2020, 10 (1), pp.16641. ⟨10.1038/s41598-020-73642-8⟩
This study evaluated the prognostic value of a panel of 29 oncogenes derived from the analysis of The Cancer Genome Atlas (TCGA data) or from the recent literature on bladder tumors on a well-characterized series of muscle-invasive bladder cancer (MI
Autor:
Costantino Pitzalis, Esteban A. Gomez, Conrad Bessant, Romain A. Colas, Rebecca Hands, Myles Lewis, Patricia R. Souza, Jesmond Dalli
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Biomarkers are needed for predicting the effectiveness of disease modifying antirheumatic drugs (DMARDs). Here, using functional lipid mediator profiling and deeply phenotyped patients with early rheumatoid arthritis (RA), we observe that peripheral
Autor:
David H. Ebb, Cassandra Garbutt, Christopher E. Lietz, Brian Lawney, Vikram Deshpande, Zhenfeng Duan, Yen-Lin Chen, Francis J. Hornicek, Dimitrios Spentzos, Santiago A. Lozano-Calderon, G. Petur Nielsen, Benjamin Haibe-Kains, Gregory M. Cote, John Quackenbush, William T. Barry, Yaoyu E. Wang, Edwin Choy
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
BackgroundThere is a lack of well validated biomarkers in osteosarcoma, a rare, recalcitrant disease with variable outcome and poorly understood biologic behavior, for which treatment standards have stalled for decades. The only standard prognostic f
Autor:
Catherine R. Marinac, Brenda M. Birmann, Jenny Soiffer, Irene M. Ghobrial, Timothy R. Rebbeck
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 2, Pp 1-8 (2020)
Multiple myeloma (MM) is a fatal plasma cell dyscrasia with a median overall survival of 5 to 10 years. MM progresses from the more common but often subclinical precursor states of monoclonal gammopathy of undetermined significance (MGUS), and smolde
Autor:
Monica Lane, Clemens R. Scherzer, Kate Zhang, Wenfei Zhang, Catherine Viel, Petra Oliva, S. Pablo Sardi, Roy N. Alcalay, Lamya S. Shihabuddin, Pavlina Wolf, Melissa S. Rotunno, Anne-Marie Wills
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Parkinson’s disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Better understanding of the underlying disease mechanism(s) is an urgent need for the development of disease-modif
Autor:
Mustafa Ascha, Jill S. Barnholtz-Sloan, Andrew E Sloan, Jacqueline Wang, Carol Kruchko, Priya Kumthekar
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Bevacizumab is FDA-approved in the treatment of primary brain tumors, but its efficacy in patients with brain metastases could be better-studied. This study examines a population of non-small cell lung cancer (NSCLC) patients with synchronous brain m
Autor:
Gene-Siew Ngian, Ali Bayoumi, Khaled Thabet, Lorenzo Beretta, Wendy Stevens, Nicholas Manolios, Kathleen Tymms, Susanna Proudman, Jane Zochling, Jacob George, Janet Roddy, Maureen Rischmueller, Mayada Metwally, Gemma Strickland, Susan C. Lester, Olfat G. Shaker, Pravin Hissaria, Mohammed Eslam, Mandana Nikpour, Christopher Liddle, Joanne Sahhar, Jennifer G Walker
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-5 (2019)
Scientific Reports
Scientific Reports
Fibrosis across different organs and tissues is likely to share common pathophysiological mechanisms and pathways. Recently, a polymorphism (rs12979860) near the interferon lambda gene (IFNL3) was shown to be associated with fibrosis in liver across
Autor:
Diane Provencher, Euridice Carmona, Benjamin K. Tsang, Anne-Marie Mes-Masson, Tien Le, Meshach Asare-Werehene, Laudine Communal
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Ovarian cancer (OVCA) patients with suboptimal residual disease (RD) and advanced stages have poor survival. pGSN is an actin binding protein which protects OVCA cells from cisplatin-induced death. There is an urgent need to discover reliable biomark
Autor:
Luisa F. Escobar-Hoyos, Lucia Roa-Peña, Kenneth R. Shroyer, Chun-Hao Pan, Jela Bandovic, Richard A. Moffitt, Cindy V. Leiton, Elizabeth A. Vanner, Ali Akalin, Sruthi Babu
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Although the overall five-year survival of patients with pancreatic ductal adenocarcinoma (PDAC) is dismal, there are survival differences between cases with clinically and pathologically indistinguishable characteristics, suggesting that there are u
Autor:
Laguzzi, Federica, Maitusong, Buamina, Strawbridge, Rona J., Baldassarre, Damiano, Veglia, Fabrizio, Humphries, Steve E., Rauramaa, Rainer, Kurl, Sudhir, Smit, Andries J., Giral, Philippe, Silveira, Angela, Tremoli, Elena, Hamsten, Anders, de Faire, Ulf, Gigante, Bruna, Leander, Karin, Sirtori, C. R., Calabresi, L., Amato, M., Frigerio, B., Ravani, A., Sansaro, D., Tedesco, C., Coggi, D., Capra, N., Bonomi, A., Eriksson, P., Cooper, J., Acharya, J., Savonen, K., Huttunen, K., Rauramaa, E., Penttila, I. M., Törrönen, J., van Gessel, A. I., van Roon, A. M., Nicolai, A., Mulder, D. J., Kontush, A., Carrié, A., Gallo, A., Karppi, J., Nurmi, T., Nyyssönen, K., Tuomainen, T. P., Tuomainen, J., Kauhanen, J., Sennblad, B., Pirro, M., Vaudo, G., Siepi, D., Lupattelli, G., Mannarino, M. R., Bianconi, V.
Publikováno v:
Scientific Reports, 11(1):7866. Nature Publishing Group
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.7866. ⟨10.1038/s41598-021-86324-w⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.7866. ⟨10.1038/s41598-021-86324-w⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
The relationship between intake of saturated fats and subclinical atherosclerosis, as well as the possible influence of genetic variants, is poorly understood and investigated. We aimed to investigate this relationship, with a hypothesis that it woul