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Autor:
Xiaohua Gong, Rongrong Le, Xiaojun Chen, Ke Xu, Shi Yujuan, Hongjin Chen, Xiaozhong Huang, Zimiao Chen, Gu Xuemei, Qihan Zhu, Feixia Shen, Chen Xiong
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the ef
Autor:
Jia Hung Liou, Jiu Yao Wang, Yi Giien Tsai, Hai Lun Sun, Yung Sung Wen, Kuender D. Yang, Ching-Yuang Lin
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Autophagy plays a major role in defending against oxidative stress in respiratory epithelial cells. The complement regulatory protein CD46 can enhance autophagy and decrease local complement activation at sites of inflammation. This study investigate
Autor:
Alvin Gomez, Angela Rico de Souza, Matthew Iu, Sarah Rogers, Michela Zago, Carolyn J. Baglole, Necola Guerrina, Jason Matthews
Publikováno v:
Scientific Reports
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically known for its toxic responses to man-made pollutants such as dioxin. More recently, the AhR has emerged as a suppressor of inflammation, oxidative stress and
Autor:
Guangzhi Wang, Xiangwen Zhang, Jing Guo, Xiaofeng Tian, Guo Zu, Anlong Ji, Ningwei Che, Tingting Zhou
Publikováno v:
Scientific Reports
Ginsenoside Rg1 (Rg1) is one of the major bioactive ingredients in Panax ginseng, and it attenuates inflammation and apoptosis. The aims of our study were to explore the potential of Rg1 for the treatment of intestinal I/R injury and to determine whe
Autor:
Yasmen F. Mahran, Reem N. El-Naga
Publikováno v:
Scientific Reports
Nephrotoxicity associated with the clinical use of the anticancer drug cisplatin is a limiting problem. Thus, searching for new protective measures is required. Indole-3-carbinol is a powerful anti-oxidant, anti-inflammatory and anti-tumor agent. The