Zobrazeno 31 - 40
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Autor:
Hilary Coon, Anna R. Docherty, Amanda V. Bakian, Eric T. Monson, Emily DiBlasi, Brooks R. Keeshin, Virginia L. Willour, Sheila E. Crowell, Niamh Mullins, Douglas Gray, Qingqin S. Li, Andrey A. Shabalin
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Translational Psychiatry
Translational Psychiatry
Bipolar disorder (BP) suicide death rates are 10–30 times greater than the general population, likely arising from environmental and genetic risk factors. Though suicidal behavior in BP has been investigated, studies have not addressed combined cli
Autor:
Chuanyin Li, Taowei Yang, Kaihui Wu, Xiao Tan, Zixian Wang, Jianming Lu, Xiangming Mao, Zining Long, Chuanfan Zhong, Weibo Zhong, Shuo Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Prostate cancer (PCa) is a common high-incidence malignancy in men, some of whom develop biochemical recurrence (BCR) in the advanced stage. However, there are currently no accurate prognostic indicators of BCR in PCa. The aim of our study was to ide
Autor:
Jieping Chen, Yanni Ma, Yali Zhang, Xiangtao Huang, Xi Li, Chengxin Luo, Guixian Wu, Mingling Xie, Feng Tian
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery
Cell Death Discovery
Mantle cell lymphoma (MCL) is highly aggressive and its treatment remains challenging, understanding its pathogenesis is critical for future targeted therapy. SUMO specific proteases 1 (SENP1) is an important protein that regulates the balance betwee
Autor:
Jing Ji, Yue Li, Bin Liu, Xiaotian Huang, Mei Ji, Zhao Zhao, Wei Liu, Zhe Li, Kaige Wang, Penglin Xu, Jia Shi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Heterogeneous nuclear ribonucleoprotein L (hnRNPL) is a type of RNA binding protein that highly expressed in a variety of tumors and plays a vital role in tumor progression. However, its post-translational regulation through ubiquitin-mediated proteo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Acquired resistance to glucocorticoids (GCs) is an obstacle to the effective treatment of leukemia, but the molecular mechanisms of steroid insensitivity have not been fully elucidated. In this study, we established an acquired GC-resistant leukemia
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Neutrophils are significant compositions of solid tumors and exert distinct functions in different types of tumors. However, the precise role of neutrophils in the progression of breast cancer (BC) is presently unclear. In this study, by investigatin
Autor:
Peng Liu, Yuehua Wei, Yinan Zhang, Jialu Li, Congrong Wang, Jiping Liu, Jiang Zhixin, Yi E. Sun, Xinfeng Yan, Xinpei Gao, Fengwen Li
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
The mitochondrial DNA m.3243A > G mutation is well-known to cause a variety of clinical phenotypes, including diabetes, deafness, and osteoporosis. Here, we report isolation and expansion of urine-derived stem cells (USCs) from patients carrying the
Autor:
Hong-Wei Wang, Huizhen Zhao, Yuelei Shen, Youchun Wang, Jiajing Wu, Weijin Huang, Jingshu Xie, Jianhui Nie, Lei Chen, Jiawei Yao, Meiyu Wang, Shuo Liu, Yabo Zhang, Jianhui Li, Liu Yacui, Chuan Liu, Yi Yang
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Cell Discovery
Cell Discovery
Coronavirus disease 2019 (COVID-19), a pandemic disease caused by the newly emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused more than 3.8 million deaths to date. Neutralizing antibodies are effective therapeutic meas
Autor:
Shengyu He, Xiao Wang, Anqi He, Zihua Jiang, Keming Yu, Zedu Cui, Xuan Liu, Shuilian Chen, Xi Chen, Pei Chen, Jing Zhuang, Nandan Wu, Qian Luo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Exosomes derived from tumor cells play a key role in tumor development. In the present study, we identified the bioactivity of exosomes released from WERI-Rb1 retinoblastoma cells in tumor angiogenesis, as well as the underlying mechanism, through bi
Autor:
Jingyan Li, Hanwei Yang, Min Huang, Wanqi Yang, Yanqi Mai, Guimei Guan, Tong Lin, Wenwei Luo, Meiting Chen, Lili Zhang, Chunmei Dai, Jing Lu, Peiqing Liu, Ruiming Liu, Ziqing Li, Zhuoming Li, Hong Li
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Heme oxygenase-1 (HO-1) has attracted accumulating attention for its antioxidant enzymatic activity. However, the exact regulatory role of its non-enzymatic activity in the cardiovascular system remains unaddressed. Here, we show that HO-1 was accumu