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Autor:
Xueyan Wang, Valentin David, Samantha Neuburg, Claire Gerber, Guillaume Courbon, Emily Lynch, Connor Francis, Myles Wolf, Jodie L. Babitt, Tamara Isakova, Aline Martin
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Bone Research
Bone Research
Bone-produced fibroblast growth factor 23 (FGF23) increases in response to inflammation and iron deficiency and contributes to cardiovascular mortality in chronic kidney disease (CKD). Neutrophil gelatinase-associated lipocalin (NGAL or lipocalin 2;
Autor:
Froukje Vanweert, Dennis O. Mook-Kanamori, Esther Phielix, Renée de Mutsert, Patrick Schrauwen, Frits R. Rosendaal, Hildo J. Lamb, Sebastiaan C. Boone, Bram Brouwers, Matthijs K. C. Hesselink, Vera B. Schrauwen-Hinderling
Publikováno v:
International Journal of Obesity (2005)
International Journal of Obesity, 45(7), 1510-1520. Nature Publishing Group
International Journal of Obesity, 45(7), 1510-1520. SPRINGERNATURE
International Journal of Obesity, 45(7), 1510-1520. Nature Publishing Group
International Journal of Obesity, 45(7), 1510-1520. SPRINGERNATURE
Aims To evaluate whether the association between plasma branched-chain amino acids (BCAA) and intrahepatic lipid (IHL) was affected by physical activity level. Furthermore, to investigate if a conventional exercise training program, a subcategory of
Autor:
Jia-Ying Wu, Yi Xiao, Yicheng Zhang, Jianfeng Zhou, Fankai Meng, Yang Cao, Na Wang, Xiaojian Zhu, Jue Wang, Lifang Huang
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 7, Pp 1-8 (2021)
Blood Cancer Journal
Blood Cancer Journal
Chimeric antigen receptor (CAR) T-cell immunotherapy following autologous stem cell transplantation (ASCT) is a promising method for refractory or relapsed multiple myeloma, but explicit data for central nervous system lymphoma (CNSL) are lacking. He
Autor:
Chuanyin Li, Taowei Yang, Kaihui Wu, Xiao Tan, Zixian Wang, Jianming Lu, Xiangming Mao, Zining Long, Chuanfan Zhong, Weibo Zhong, Shuo Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Prostate cancer (PCa) is a common high-incidence malignancy in men, some of whom develop biochemical recurrence (BCR) in the advanced stage. However, there are currently no accurate prognostic indicators of BCR in PCa. The aim of our study was to ide
Autor:
Marina Quinlan, Maria Rogdaki, Alaine Berry, Anthony C. Vernon, Thomas Whitehurst, Sridhar Natesan, Ellis Chika Onwordi, Ben Statton, Roger N. Gunn, Tiago Reis Marques, Oliver D. Howes, Ayla Mansur, Declan P. O'Regan, Eugenii A. Rabiner
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Translational Psychiatry
Glutamatergic excitotoxicity is hypothesised to underlie synaptic loss in schizophrenia pathogenesis, but it is unknown whether synaptic markers are related to glutamatergic function in vivo. Additionally, it has been proposed that N-acetyl aspartate
Autor:
Lunguang Yao, Dandan Li, Juan Xing, Zhongyu Qu, Jiawei Zhou, Qian Xu, Qian Ding, Yugang Guo, Fanghui Bai
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Cell Death Discovery
Cell Death Discovery
Ferroptosis is closely linked to various cancers, including lung adenocarcinoma (LUAD); however, the factors involved in the regulation of ferroptosis-related genes are not well established. In this study, we identified and characterized ferroptosis-
Autor:
Robert A. Swor, Sarah D. Linnstaedt, Andrew S. Tungate, David A. Peak, Jarred J. Lobo, Niels K. Rathlev, Samuel A. McLean, Phyllis L. Hendry
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Translational Psychiatry
Posttraumatic stress (PTS), depressive symptoms (DS), and musculoskeletal pain (MSP) are common sequelae of trauma exposure. Although these adverse posttraumatic neuropsychiatric sequelae (APNS) are often studied separately, clinical comorbidity is h
Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner
Autor:
Jessica R Doll, Claire A. Chougnet, Traci E. Stankiewicz, Maria E. Moreno-Fernandez, Vishakha Sharma, Jarren R Oates, Senad Divanovic, Maha Almanan, David A. Hildeman, Michelle S M A Damen
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-13 (2021)
Nutrition & Diabetes
Nutrition & Diabetes
Background Understanding gender-associated bias in aging and obesity-driven metabolic derangements has been hindered by the inability to model severe obesity in female mice. Methods Here, using chow- or high fat diet (HFD)-feeding regimens at standar
Autor:
Qiang Dong, Shi-Dong Chen, Xue-Ning Shen, Yu-Yuan Huang, Yu Guo, Jin-Tai Yu, Lan Tan, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Translational Psychiatry
Translational Psychiatry
To assess plasma phosphorylated tau181 (p-tau181) as a progression biomarker in Alzheimer’s disease (AD), we examined longitudinal plasma p-tau181 of 1184 participants (403 cognitively normal (CN), 560 patients with mild cognitive impairment (MCI),
Autor:
Karen L. Talia, Britta Weigelt, Yoshiki Mikami, Esther Oliva, Cathleen Matrai, Pier Selenica, W. Glenn McCluggage, Emanuela Veras, Yaser R. Hussein, Regina G. H. Beets-Tan, Takako Kiyokawa, Barbara Alemar, Kay J. Park, Rajmohan Murali
Publikováno v:
Modern Pathology, 34(6), 1213-1225. Nature Publishing Group
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Gastric-type cervical adenocarcinoma (GCA) is an aggressive type of endocervical adenocarcinoma characterized by mucinous morphology, gastric-type mucin, lack of association with human papillomavirus (HPV) and resistance to chemo/radiotherapy. We cha