Zobrazeno 31 - 40
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Autor:
Anna Ianza, Monica Ramello, Enrico Mini, Giandomenico Roviello, Alberto D'Angelo, Martina Catalano, Raffaele Conca, Lorenzo Dreoni, Roberto Petrioli, Stefania Nobili, Silvia Gasperoni, Michele Aieta
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Neutropenia is a common side effect associated with nab-paclitaxel gemcitabine (Nab-Gem) therapy. We retrospectively investigated the association between neutropenia induced by first-line Nab-Gem and survival in metastatic pancreatic carcinoma patien
Autor:
Chengwei Tang, Xiao Ma, Ming Zhou, Chong Zhao, Libin Huang, Jinhang Gao, Huan Tong, Rui Liu, Qinghua Tan, Zhe Feng, Jinsun Jiang, Ling Liu, Ming-Guang Zhang, Zhiyin Huang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Duodenal dysbiosis may be potential infection risks in patients with severe acute pancreatitis (SAP). Acid-suppression drugs (ACDs) are widely used in SAP patients in Asian countries. However, the impact of ACDs on duodenal microbiota during the earl
Autor:
Jun-Hyeok Kang, Wen-Fang Cheng, Yoo-Young Lee, Yen-Ling Lai, Hyun Soo Kim, Kuan-Ting Kuo, Yu-Li Chen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Low-grade ovarian serous carcinoma (LGSOC) has clinical features different from high-grade serous ovarian carcinoma (HGSOC) accounting for the majority of epithelial ovarian cancer. Because of its rarity, previous studies have only focused on the hig
Autor:
Waldemar Patkowski, Zbigniew Lewandowski, Marek Krawczyk, Karolina Grąt, Michał Grąt, Krzysztof Zieniewicz, Maciej Krasnodębski, Łukasz Masior
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Perioperative use of probiotics serves as efficient prophylaxis against postoperative infections after liver transplantation, yet data on long-term effects of pre-transplant probiotic intake is lacking. The aim of this study was to assess the effects
Autor:
Ruey Hsing Chou, Shao Sung Huang, Po Hsun Huang, Chun Chin Chang, Shing Jong Lin, Ya Wen Lu, Shen-Chih Wang, Yi Lin Tsai, Chin Sung Kuo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Galectin-1, a β-galactoside-binding lectin mediating inflammation and neovascularization, is reported to attenuate ventricular remodeling after myocardial infarction. But its role in stable coronary artery disease (CAD) has not been fully elucidated
Autor:
Yoshitaka Isaka, Isao Matsui, Ayumi Matsumoto, Kazunori Inoue, Yusuke Katsuma, Seiichi Yasuda, Ken Sugimoto, Yoshitsugu Takabatake, Minoru Tanaka, Jun-ya Kaimori, Karin Shimada, Yusuke Sakaguchi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Dietary phosphate intake is closely correlated with protein intake. However, the effects of the latter on phosphate-induced organ injuries remain uncertain. Herein, we investigated the effects of low (10.8%), moderate (23.0%), and high (35.2%) dietar
Autor:
Bethania Fernandes, Massimo Roncalli, Corrado Tinterri, Alberto Testori, Giovanna Masci, Wolfgang Gatzemeier, Elisa Agostinetto, Agnese Losurdo, Rita De Sanctis, Valentina Errico, Armando Santoro, Rosalba Torrisi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Triple negative breast cancer (TNBC), usually presenting with a very aggressive phenotype, is a heterogeneous entity. We aim to discuss new biomarkers, suitable for prognostic and predictive purposes. We retrospectively collected clinical variables a
Autor:
Paschalis Ntolios, George Kouliatsis, Georgia Karpathiou, Evangelia Nakou, Ioannis Kotsianidis, Demosthenes Bouros, Stavros Anevlavis, Marios Froudarakis, Argyrios Tzouvelekis, Vasilios Mihailidis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Published articles support the effect of chemotherapy in the immune environment of tumors, including lung carcinomas. The role of CD4 + T-cells is crucial for expansion and accumulation of other antigen-specific immune cells, and the participation of
Autor:
Xueli Bai, Xing Huang, Tingbo Liang, Zhengtao Hong, Tianyu Tang, Dipesh Kumar Yadav, Jian Xu, Gang Zhang
Publikováno v:
npj Precision Oncology, Vol 4, Iss 1, Pp 1-15 (2020)
NPJ Precision Oncology
NPJ Precision Oncology
Drugs that target immune checkpoints (ICPs) have become the most popular weapons in cancer immunotherapy; however, they are only beneficial for a small fraction of patients. Accumulating evidence suggests that the tumor immune microenvironment (TIME)
Autor:
Michael F. Press, Ali Madani, Nitish Shirish Keskar, David B. Agus, Daniel Ruderman, Nikhil Naik, Richard Socher, Andre Esteva
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications
Nature Communications
For newly diagnosed breast cancer, estrogen receptor status (ERS) is a key molecular marker used for prognosis and treatment decisions. During clinical management, ERS is determined by pathologists from immunohistochemistry (IHC) staining of biopsied