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Autor:
Michael R. Munday, Vijay Kumar, Zainab Al-Abadla, Salahedeen Abusnana, Asma M. Fikri, Rosemary Smyth
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Currently, type 2 diabetes mellitus (T2DM) and obesity are major global public health issues, and their prevalence in the United Arab Emirates (UAE) are among the highest in the world. In 2019, The UAE diabetes national prevalence was 15.4%. In recen
Autor:
Jiao Chen, Wang Ziwen, Huaqiang Liao, Zhang Yutong, Chen Wang, Ling Zhao, Shi Yu, Tao Xu, Fanrong Liang, Dehua Li, Siyuan Zhou, Siying Huang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
The pathophysiological differences between menstrually-related migraine (MRM) and pure menstrual migraine (PMM) are largely unclear. The aim of this study was to investigate the potential differences in brain structure and function between PMM and MR
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Though the patients with sickle cell anemia (SCA) inherit same genetic mutation, they show considerable phenotypic heterogeneity. It has been observed that patients with elevated fetal hemoglobin (HbF) levels have a relatively mild clinical course. T
Autor:
Wenjing Qiao, Yiran Chong, Hailong Zhu, Jiayi Zhang, Shitao Zhao, Shutian Zhang, Yi Zhao, Wei Tao, Gang Wu, Ann M Vuong, De-Miao Zhu, Tianyi Wang, Baihui Tao, Jin-Cheng Li, Mengmeng Niu, Shuman Yang, Shuang Ma
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
Scientific Reports
Scientific Reports
In vivo and vitro evidence indicates that ornithine and its related metabolic products play a role in tumor development. Whether ornithine is associated with breast cancer in humans is still unclear. We examined the association between circulating or
Autor:
Merja Haaparanta-Solin, Jukka Laine, Markku Taittonen, Mueez U-Din, Pirjo Nuutila, Nina Savisto, Kirsi A. Virtanen, Juho Raiko, Tarja Niemi, Teemu Saari
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Fatty acids (FA) are important substrates for brown adipose tissue (BAT) metabolism, however, it remains unclear whether there exists a difference in FA metabolism of BAT between lean and obese healthy humans. In this study we evaluated supraclavicul
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
The inflammatory process is known to increase the risk of gastric carcinogenesis, and both genetic and dietary factors are associated with inflammation. In the present study of 1,125 participants (373 cases and 752 controls), we determined whether th
Autor:
Pi-Hua Liu, Hsiao-Lin Lee, Chen-Yang Shen, Chen-Hao Huang, Ru-Yi Tsai, Yi-Cheng Chang, Wei-Shun Yang, Meng-Lun Hsieh, Yu-Yao Huang, Chia-Ni Hsiung, Chia-Hung Lin, Chih-Neng Hsu, Jou-Wei Lin, Cassianne Robinson-Cohen, Tsui-Wei Chyan, Gwo-Tsann Chuang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Fibroblast growth factors (FGFs) 21 and 23 are recently identified hormones regulating metabolism of glucose, lipid, phosphate and vitamin D. Here we conducted a genome-wide association study (GWAS) for circulating FGF21 and FGF23 concentrations to i
Autor:
Nicolas Flamand, Benoît Lamarche, Frédéric Raymond, Julie Perron, Lydiane Parent, Vincenzo Di Marzo, Alain Veilleux, Gabrielle Rochefort, Sébastien Lacroix, Cyril Martin, Sophie Castonguay-Paradis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-72861-3
info:cnr-pdr/source/autori:Castonguay-Paradis, Sophie; Lacroix, Sebastien; Rochefort, Gabrielle; Parent, Lydiane; Perron, Julie; Martin, Cyril; Lamarche, Benoit; Raymond, Frederic; Flamand, Nicolas; Di Marzo, Vincenzo; Veilleux, Alain/titolo:Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat/doi:10.1038%2Fs41598-020-72861-3/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Scientific Reports
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-72861-3
info:cnr-pdr/source/autori:Castonguay-Paradis, Sophie; Lacroix, Sebastien; Rochefort, Gabrielle; Parent, Lydiane; Perron, Julie; Martin, Cyril; Lamarche, Benoit; Raymond, Frederic; Flamand, Nicolas; Di Marzo, Vincenzo; Veilleux, Alain/titolo:Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat/doi:10.1038%2Fs41598-020-72861-3/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Scientific Reports
The endocannabinoidome encompasses several fatty acid (FA)-derived mediators, including the endocannabinoid anandamide (AEA) and 2-arachidonoyl-glycerol (2-AG), which served as targets for anti-obesity drug development, and their congener N-acyl-etha
Autor:
Yusuke Tsuchimoto, Masahiro Matsui, Akira Asai, Kazuhisa Uchiyama, Kazuhide Higuchi, Yoshihiro Inoue, Hideko Ohama, Tomohiro Nishikawa, Norio Okamoto, Keisuke Yokohama, Shinya Fukunishi, Hidetaka Yasuoka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Immune-related adverse events (irAEs) are induced by immune checkpoint inhibitors (ICIs). Liver is one of the main target organs which irAEs occur and we investigated the influence of liver dysfunction on prognosis of patients after ICIs. From July 2
Autor:
Tingting Su, Shuang Ren, Bixun Li, Wei-Yuan Wei, Cheng-En Deng, Lu-Huai Feng, Zhenhua Yang, Kunpeng Bu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Colorectal cancer remains a major health burden worldwide and is closely related to type 2 diabetes. This study aimed to develop and validate a colorectal cancer risk prediction model to identify high-risk individuals with type 2 diabetes. Records of