Zobrazeno 101 - 110
of 427
pro vyhledávání: ''
Autor:
Guohui Li, Da-Cheng Wang, Siying Qin, Kai Zhang, Can Xie, Hang Yin, Fei Sun, Yukun Guan, Run Fang, Honglei Wang, Fangwei Leng, Zhengfan Jiang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
NOD-like receptors (NLRs) localize in the cytosol to recognize intracellular pathogen products and initialize the innate immune response. However, the ligands and ligand specificity of many NLRs remain unclear. One such NLR, NLRP6, plays an important
Autor:
João F. Passos, Anthony B. Lagnado, Elizabeth J. Soilleux, Katerina Pyrillou, Rebecca Brais, Nicholas T. Ktistakis, Liam D. Cassidy, Diana Jurk, Bettina M. Weigand, Masashi Narita, Murray C.H. Clarke, Kimberley A. Wiggins, Edward Fielder, Andrew R. J. Young, Christopher N. J. Young
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Autophagy is an important cellular degradation pathway with a central role in metabolism as well as basic quality control, two processes inextricably linked to ageing. A decrease in autophagy is associated with increasing age, yet it is unknown if th
Autor:
Kyung Hee Park, Heejae Han, Hye Jung Park, Jung Won Park, Kyoung Yong Jeong, Eun-Yi Oh, Jae Hyun Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
CD93 has been shown critical roles in inflammatory and immune diseases. However, in allergic asthma, the potential roles of soluble CD93 (sCD93) have not been well studied. We conducted house dust mite (HDM) stimulation with Der p 1 in BEAS-2B and U9
Autor:
Manish Kumar, Aralia Leon Coria, Steve Cornick, Björn Petri, Shyamchand Mayengbam, Humberto B. Jijon, France Moreau, Jane Shearer, Kris Chadee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Inflammatory bowel disease is associated with changes in the mucosal barrier, increased intestinal permeability, and increased risk of infections and sepsis, but the underlying mechanisms are incompletely understood. Here, we show how continuous tran
Autor:
Zhe Jiao, Guofu Cheng, Lintao Li, Xueying Hu, Xue Wang, Xiaoli Liu, Yanchuan Li, Wanpo Zhang, Changqin Gu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Swine pneumonia is a great threat for pig industry around the world, which is usually accompanied with neutrophils infiltration in the airway. Although interleukin-8 (CXCL8) and its receptors, CXC chemokine receptor 1 and 2 (CXCR1/2) in human have be
Autor:
Lin Lin, Guixuan Pan, Sheng Zhang, Majuan Zhang, Zhenqiang You, Hao Chen, Jiaoting Chen, Yaoxian Xuan, Yin Wang, Lili Li
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
The anti-inflammatory activity of Quzhou Fructus Aurantii Extract (QFAE) has been reported recently. Thus, present study aims to explore the mechanism of anti-inflammation of QFAE in vitro and in vivo to develop a lung phylactic agent. The anti-infla
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Societal lifestyle changes, especially increased consumption of a high-fat diet lacking dietary fibers, lead to gut microbiota dysbiosis and enhance the incidence of adiposity and chronic inflammatory disease. We aimed to investigate the metabolic ef
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Time perception is an important ability that is related closely to humans’ and animals’ daily activities. It can be distorted by various emotional states. In human studies, experimental pain has been shown to prolong the perception of time. Howev
Autor:
Snezana Brkic, Dajana Lendak, Vojislava Bugarski Ignjatović, Jasmina Boban, Aleksandar Todorovic, Majda M. Thurnher, Dusko Kozic
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
There is a lack of data about the long-term follow-up changes in neurometabolic profile and neuropsychological performance of HIV-positive subjects under continuous antiretroviral therapy (cART). The aim of the study was to assess changes in neuromet
Autor:
Qin Tang, Yiqing Zhou, Huanhuan Luo, Weiwei Hu, Guang-Li Rong, Weizhong Guo, Song Chen, Yuhua Zheng, Jianbang Tang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
High temperature and humidity (HTH) can cause diarrhea owing to food and drinking water contamination. However, their direct effects on gut microbiota and gastrointestinal inflammation are unknown. This study aimed to investigate the effects of HTH a