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Autor:
C. M. Broughton, Arturas Grauslys, Rebecca Jennings, S. Siner, Stéphane Paulus, Paul Baines, Marie M. Phelan, Enitan D. Carrol
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Sepsis, defined as life-threatening organ dysfunction caused by infection is difficult to distinguish clinically from infection or post-operative inflammation. We hypothesized that in a heterogeneous group of critically ill children, there would be d
Autor:
Yan-Hong Li, Bin-Bin Fang, Xiao-Mei Li, Xiao-Ming Gao, Fen Liu, Jun-Yi Luo, Ting Tian, Yi-Ning Yang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Myocardial infarction (MI), the leading cause of mortality and disability worldwide, is a disease in which multiple environmental and genetic factors are involved. Recently, researches suggested that insertion/deletion (ins/del) variation of NFKB1 ge
Autor:
Hanne Vanheel, Tim Vanuytsel, Silvia Cocca, Guy E. Boeckxstaens, Ricard Farré, Alison Accarie, Dorien Beeckmans, Gianluca Matteoli, Hans-Reimer Rodewald, María Vicario, Joran Toth, Jan Tack, Lucas Wauters, Gert De Hertogh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Duodenal hyperpermeability and low-grade inflammation in functional dyspepsia is potentially related to duodenal acid exposure. We aimed to evaluate in healthy volunteers the involvement of mast cell activation on the duodenogastric reflex and epithe
Autor:
Pedro J. Sánchez-Cordón, John Spiropoulos, Daryan A. Kaveh, Philip J. Hogarth, M. Carmen Garcia-Pelayo, Naomi Bull
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Heterologous BCG prime-boost regimens represent a promising strategy for an urgently required improved tuberculosis vaccine. Identifying the mechanisms which underpin the enhanced protection induced by such strategies is one key aim which would signi
Autor:
Darren Roblyer, Yanyu Zhao, John P. Dumas, Mark C. Pierce, Hannah M. Peterson, Jon C. Aster, Anahita Pilvar, John Jiang, Anup Tank
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Water and lipids are key participants in many biological processes, but there are few non-invasive methods that provide quantification of these components in vivo, and none that can isolate and quantify lipids in the blood. Here we develop a new imag
Autor:
Ho-Man Kan, Cato T. Laurencin, Takayoshi Otsuka, Rosalie Bordett, Maumita Bhattacharjee, Lakshmi S. Nair, Jorge L. Escobar Ivirico, Rishikesh Pandey
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Inflammation leads to chondrocyte senescence and cartilage degeneration, resulting in osteoarthritis (OA). Adipose‐derived stem cells (ADSCs) exert paracrine effects protecting chondrocytes from degenerative changes. However, the lack of optimum de
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
The inflammatory process is known to increase the risk of gastric carcinogenesis, and both genetic and dietary factors are associated with inflammation. In the present study of 1,125 participants (373 cases and 752 controls), we determined whether th
Autor:
Gaël Cobraiville, Philippe Delvenne, Dominique de Seny, Elettra Bianchi, Marie-Joëlle Kaiser, Michel Malaise, Gabriel Mazzucchelli, Jean-Philippe Hauzeur, Dominique Baiwir, Charlotte Collin, Mégane Deliège
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
It is now well recognized that osteoarthritis (OA) synovial membrane presents inflammatory components. The aim of this work is to provide evidence that similar inflammatory mechanisms exist in synovial membrane (n = 24) obtained from three pathologie
Autor:
Alireza Faridar, Shixiang Wen, Jason R. Thonhoff, Aaron D. Thome, David R. Beers, Weihua Zhao, Jinghong Wang, Daniel Neal, Stanley H. Appel
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Amyotrophic lateral sclerosis (ALS) is a multifactorial, multisystem pro-inflammatory neuromuscular disorder compromising muscle function resulting in death. Neuroinflammation is known to accelerate disease progression and accentuate disease severity
Autor:
Zijie Yuan, Youde Cao, Yonghua Yuan, Zhonghua Deng, Yanghua Yue, Jie Chen, Lu Wang, Menghua Zhao, Chaochao Tan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Kawasaki disease (KD) is a multi-systemic vasculitis of unknown etiology that occurs mainly in children, and the disturbance of gut microbiota is generally believed to cause a hyperimmune reaction triggering KD. The aim of the study was to investigat